{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T09:37:40Z","timestamp":1789205860263,"version":"build-2803163510"},"reference-count":27,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2017,11,22]],"date-time":"2017-11-22T00:00:00Z","timestamp":1511308800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2018,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>We sought to investigate the long\u2010term clinical outcomes of patients with coronary artery aneurysm (CAA) after drug\u2010eluting stent (DES) implantation, compared with patients without CAA.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>CAA developed after DES implantation is a rare but associated with poor clinical outcome.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We retrospectively compared 78 patients with CAA after DES implantation with 269 patients without CAA who underwent DES implantation for complex lesions (controls). The primary endpoint was defined as major adverse cardiac events (MACE), the composite of all\u2010cause death, nonfatal myocardial infarction (MI), and target lesion revascularization (TLR).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Morphologically, CAAs were saccular (32%), fusiform (13%), or microform (55%). The stent types involved were Cypher (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200956, 71.8%) and Taxus (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200922, 28.2%). During a median follow\u2010up period of 1164 days, the incidence of MACE was significantly higher in the CAA group (26.9 vs. 2.2%,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u20090.001); the difference was driven mainly by nonfatal MI (11.5 vs. 0%,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u20090.001) and TLR (20.5 vs. 1.9%,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u20090.001). The incidence of stent thrombosis was higher in the CAA group (12.8 vs. 0.74%,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u20090.001), irrespective of the maintenance of dual antiplatelet therapy. In the CAA group, Cox regression analysis showed significantly higher hazard ratios of CAA for MACE during the follow\u2010up period. Further analyses after propensity\u2010score matching of 65 pairs also showed similar results.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The incidence of MACE was higher in patients with CAA compared with patients without CAA after DES implantation. This difference was driven by TLR and nonfatal MI and widened over time.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ccd.27429","type":"journal-article","created":{"date-parts":[[2017,11,22]],"date-time":"2017-11-22T00:46:52Z","timestamp":1511311612000},"source":"Crossref","is-referenced-by-count":23,"title":["Clinical outcomes of patients with coronary artery aneurysm after the first generation drug\u2010eluting stent implantation"],"prefix":"10.1002","volume":"92","author":[{"given":"Hyung Joon","family":"Joo","sequence":"first","affiliation":[{"name":"Department of Cardiology Cardiovascular Center, Korea University Anam Hospital, Anam\u2010dong Sungbuk\u2010ku Seoul 136\u2010705 Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cheol","family":"Woong Yu","sequence":"additional","affiliation":[{"name":"Department of Cardiology Cardiovascular Center, Korea University Anam Hospital, Anam\u2010dong Sungbuk\u2010ku Seoul 136\u2010705 Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"RakKyeong","family":"Choi","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Sejong Hospital and Sejong Heart Institute  Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinsik","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Sejong Hospital and Sejong Heart Institute  Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyun Jong","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Sejong Hospital and Sejong Heart Institute  Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Je Sang","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Sejong Hospital and Sejong Heart Institute  Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Young Jin","family":"Choi","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Sejong Hospital and Sejong Heart Institute  Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jae Hyoung","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Cardiology Cardiovascular Center, Korea University Anam Hospital, Anam\u2010dong Sungbuk\u2010ku Seoul 136\u2010705 Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Soon Jun","family":"Hong","sequence":"additional","affiliation":[{"name":"Department of Cardiology Cardiovascular Center, Korea University Anam Hospital, Anam\u2010dong Sungbuk\u2010ku Seoul 136\u2010705 Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5751-5177","authenticated-orcid":false,"given":"Do Sun","family":"Lim","sequence":"additional","affiliation":[{"name":"Department of Cardiology Cardiovascular Center, Korea 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