{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,9]],"date-time":"2025-11-09T03:40:17Z","timestamp":1762659617065,"version":"3.37.3"},"reference-count":22,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2018,1,4]],"date-time":"2018-01-04T00:00:00Z","timestamp":1515024000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100008497","name":"Boston Scientific Corporation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008497","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2018,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To determine permanent pacemaker (PPM) dependency following transcatheter aortic valve replacement (TAVR) with the Lotus<jats:sup>\u2122<\/jats:sup> valve system (Boston Scientific), and the impact of PPM implantation on long\u2010term morbidity and mortality.<\/jats:p><\/jats:sec><jats:sec><jats:title>Background<\/jats:title><jats:p>Conduction abnormalities are among the most common complications following TAVR. Limited studies have assessed pacing dependency following TAVR.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Consecutive patients (<jats:italic>n<\/jats:italic>\u2009=\u2009166) with severe aortic stenosis who underwent TAVR with the Lotus valve system were prospectively recruited from a single\u2010center. PPMs were implanted according to standard clinical criteria. Patients were followed in\u2010hospital and at 1, 3, 6, and 12 months to determine pacemaker dependency and clinical outcomes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Fourteen patients with a pre\u2010existing PPM (8%) were excluded with the remaining 152 patients aged 83.6\u2009\u00b1\u20095.6 years and 46% male. PPMs were implanted 3.8\u2009\u00b1\u20094 days post\u2010TAVR in 38\/152 patients (25%). Indication for PPM was complete heart block in 29 (76%) of patients. At 30\u2010day and one\u2010year follow up, 57% and 38% of patients were pacemaker dependent, respectively. The mean ventricular pacing percentage decreased in the first three months after PPM implantation and remained relatively stable after that.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Only 38% of Lotus recipients who require a PPM following TAVR with the Lotus valve remain pacing dependent at one year.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccd.27463","type":"journal-article","created":{"date-parts":[[2018,1,4]],"date-time":"2018-01-04T08:38:37Z","timestamp":1515055117000},"page":"777-782","source":"Crossref","is-referenced-by-count":11,"title":["Long\u2010term pacemaker dependency and impact of pacing on mortality following transcatheter aortic valve replacement with the LOTUS valve"],"prefix":"10.1002","volume":"92","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4846-2875","authenticated-orcid":false,"given":"Mohammad","family":"Alasti","sequence":"first","affiliation":[{"name":"Monash Cardiac Rhythm Management Department MonashHeart, Monash Medical Centre Melbourne Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1879-7172","authenticated-orcid":false,"given":"Hashrul","family":"Rashid","sequence":"additional","affiliation":[{"name":"Monash Cardiovascular Research Centre, MonashHeart, Monash Medical Centre and Monash University Melbourne Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karthikeyan","family":"Rangasamy","sequence":"additional","affiliation":[{"name":"Monash Cardiac Rhythm Management Department MonashHeart, Monash Medical Centre Melbourne Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emily","family":"Kotschet","sequence":"additional","affiliation":[{"name":"Monash Cardiac Rhythm Management Department MonashHeart, Monash Medical Centre Melbourne Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Adam","sequence":"additional","affiliation":[{"name":"Monash Cardiac Rhythm Management Department MonashHeart, Monash Medical Centre Melbourne Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeff","family":"Alison","sequence":"additional","affiliation":[{"name":"Monash Cardiac Rhythm Management Department MonashHeart, Monash Medical Centre Melbourne Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert","family":"Gooley","sequence":"additional","affiliation":[{"name":"Monash Cardiovascular Research Centre, MonashHeart, Monash Medical Centre and Monash University Melbourne Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sarah","family":"Zaman","sequence":"additional","affiliation":[{"name":"Monash Cardiovascular Research Centre, MonashHeart, Monash Medical Centre and Monash University Melbourne 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