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Most of these comprise of either an antegrade transseptal approach, or a retrograde transaortic or transapical approach. We herein report a novel percutaneous mitral PVL closure technique that was safely and successfully performed after failed attempt using a conventional antegrade approach.<\/jats:p>","DOI":"10.1002\/ccd.27482","type":"journal-article","created":{"date-parts":[[2018,1,13]],"date-time":"2018-01-13T13:46:59Z","timestamp":1515851219000},"page":"1196-1200","source":"Crossref","is-referenced-by-count":2,"title":["Retrograde transmitral paravalvular leak closure through an antegrade transseptal approach: A novel technique"],"prefix":"10.1002","volume":"92","author":[{"given":"Roberto J.","family":"Cubeddu","sequence":"first","affiliation":[{"name":"Department of Cardiology Cleveland Clinic Florida Weston Florida"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7301-7223","authenticated-orcid":false,"given":"Hector J.","family":"Crespo","sequence":"additional","affiliation":[{"name":"Department of Cardiology Cleveland Clinic Florida Weston Florida"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gian M.","family":"Novaro","sequence":"additional","affiliation":[{"name":"Department of Cardiology Cleveland Clinic Florida Weston Florida"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,1,13]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(00)00834-2"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1136\/heart.89.11.1316"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1010-7940(99)00358-9"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/5.suppl_D.73"},{"key":"e_1_2_6_6_1","first-page":"503","article-title":"Paraprosthetic leak: A complication of cardiac valve replacement","volume":"31","author":"Jindani A","year":"1991","journal-title":"J Cardiovasc Surg (Torino)"},{"key":"e_1_2_6_7_1","first-page":"160","article-title":"Reoperation for aortic valve periprostehetic leakage: Identification of patients at risk and results of operation","volume":"4","author":"Miller DL","year":"1995","journal-title":"J Heart Valve Dis"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2014.02.536"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/0735-1097(92)90250-Q"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2011.03.074"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCINTERVENTIONS.110.960955"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.4244\/EIJ-D-16-00581"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.20795"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2011.11.007"},{"key":"e_1_2_6_15_1","doi-asserted-by":"crossref","unstructured":"BullesfeldL MeierB.Treatment of paravalvular leaks through interventional techniques. 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