{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,8]],"date-time":"2026-01-08T19:18:35Z","timestamp":1767899915765,"version":"3.49.0"},"reference-count":25,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2018,2,26]],"date-time":"2018-02-26T00:00:00Z","timestamp":1519603200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"This research received no specific grant from any funding agency in the public commercial or not-for-profit sectors."}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2018,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Studies comparing drug coated balloons (DCB) with new generation drug\u2010eluting stents (nDES) for the treatment of de novo coronary artery lesions are lacking.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>From 2009 to 2016, DCB or nDES used for treatment of de novo coronary lesions at our institution were included, in total 1,197 DEB and 6,458 nDES. We evaluated target lesions restenosis (TLR) and definite target lesion thrombosis (TLT). Propensity score modeling were utilized to study adjusted associations between treatment and outcomes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Median follow\u2010up was 901days. DCB patients were older, with higher cardiovascular risk profile. Bailout stenting after DCB was performed in 8% of lesions. The cumulative rate of TLR and TLT was 7.0 vs. 4.9% and 0.2 vs. 0.8% for DCB vs. nDES, respectively. Before adjustment, DCB was associated with a higher risk of TLR [hazard ratio (HR) 1.44; 95% confidence interval (CI) 1.07\u20131.94] and a non\u2010significantly lower risk of TLT (HR 0.30; 95% CI 0.07\u20131.24), compared to nDES. In the propensity matched population consisted of 1,197 DCB and 1,197 nDES, treatment with DCB was associated with similar risk for TLR (adjusted HR 1.05; 95% CI 0.72\u20131.53) but significantly lower risk for TLT (adjusted HR 0.18; 95% CI 0.04\u20130.82) compared to nDES.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Treatment with DCB was associated with a similar risk of TLR and a lower risk of definite TLT compared with nDES. In selected cases, DCB appears as a good alternative to nDES for the treatment of de novo coronary lesions.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccd.27548","type":"journal-article","created":{"date-parts":[[2018,2,26]],"date-time":"2018-02-26T20:01:05Z","timestamp":1519675265000},"source":"Crossref","is-referenced-by-count":45,"title":["Long\u2010term efficacy of drug coated balloons compared with new generation drug\u2010eluting stents for the treatment of de novo coronary artery lesions"],"prefix":"10.1002","volume":"92","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5263-875X","authenticated-orcid":false,"given":"Dimitrios","family":"Venetsanos","sequence":"first","affiliation":[{"name":"Department of Cardiology Link\u00f6ping University Link\u00f6ping Sweden"},{"name":"Department of Medical and Health Sciences Link\u00f6ping University Link\u00f6ping Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sofia Sederholm","family":"Lawesson","sequence":"additional","affiliation":[{"name":"Department of Cardiology Link\u00f6ping University Link\u00f6ping Sweden"},{"name":"Department of Medical and Health Sciences Link\u00f6ping University Link\u00f6ping Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Georgios","family":"Panayi","sequence":"additional","affiliation":[{"name":"Department of Cardiology Link\u00f6ping University Link\u00f6ping Sweden"},{"name":"Department of Medical and Health Sciences Link\u00f6ping University Link\u00f6ping Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tim","family":"T\u00f6dt","sequence":"additional","affiliation":[{"name":"Department of Cardiology Clinical Sciences, Lund University, Skane University Hospital Lund Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ulf","family":"Berglund","sequence":"additional","affiliation":[{"name":"Department of Cardiology Link\u00f6ping University Link\u00f6ping Sweden"},{"name":"Department of Medical and Health Sciences Link\u00f6ping University Link\u00f6ping Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eva","family":"Swahn","sequence":"additional","affiliation":[{"name":"Department of Cardiology Link\u00f6ping University Link\u00f6ping Sweden"},{"name":"Department of Medical and Health Sciences Link\u00f6ping University Link\u00f6ping Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joakim","family":"Alfredsson","sequence":"additional","affiliation":[{"name":"Department of Cardiology Link\u00f6ping University Link\u00f6ping Sweden"},{"name":"Department of Medical and Health Sciences Link\u00f6ping University Link\u00f6ping Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,2,26]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehu278"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMe0706859"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehp275"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000121358.26097.06"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehv205"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(00)00614-8"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(12)61964-3"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.4244\/EIJV9I5A99"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.2010.195057"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2012.09.020"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/joic.12227"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2012.07.040"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.4244\/EIJV9I5A98"},{"key":"e_1_2_8_15_1","unstructured":"Hamm CW. Paclitaxel\u2010eluting PTCA\u2010balloon in combination with the Coroflex blue stent vs. the sirolimus coated Cypher stent in the treatment of advanced coronary artery disease; PEPCAD III. Paper presented at the American Heart Associatiobn Scientific Seessions Nov 14 2009 Orlando FL USA."},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.4244\/EIJV8I4A70"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00392-013-0609-7"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/sim.2580"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1136\/heartjnl-2013-304881"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2013.07.161"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00392-009-0101-6"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2012.08.007"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehs086"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.293.17.2126"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2012.02.027"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehv203"}],"container-title":["Catheterization and Cardiovascular Interventions"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fccd.27548","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccd.27548","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,15]],"date-time":"2023-09-15T06:01:20Z","timestamp":1694757680000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccd.27548"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,2,26]]},"references-count":25,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2018,11]]}},"alternative-id":["10.1002\/ccd.27548"],"URL":"https:\/\/doi.org\/10.1002\/ccd.27548","archive":["Portico"],"relation":{},"ISSN":["1522-1946","1522-726X"],"issn-type":[{"value":"1522-1946","type":"print"},{"value":"1522-726X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,2,26]]}}}