{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,11]],"date-time":"2026-03-11T23:18:24Z","timestamp":1773271104901,"version":"3.50.1"},"reference-count":16,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2018,3,9]],"date-time":"2018-03-09T00:00:00Z","timestamp":1520553600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2018,11,15]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Bioresorbable coronary scaffolds (BRS) have been developed to increase the late safety of coronary angioplasty by providing transitory coronary support and then being fully incorporated to the vessel wall. In the present trial, we sought to evaluate the performance and changes over time in the DESolve\u2122 novolimus\u2010eluting BRS using serial intravascular ultrasound (IVUS) in patients submitted to percutaneous coronary interventions.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Single\u2010center, prospective, non\u2010randomized study involving 17 consecutive patients submitted to implantation of the DESolve\u2122 scaffold and serial evaluated with IVUS at different time points (post procedure, 6 and 18 months). Primary endpoint included the variation in lumen, scaffold, and vessel diameter and area along the months.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Angiographic success was achieved in all cases. Scaffold area and volume on IVUS were significantly greater at 6 months than at baseline (6.41\u2009\u00b1\u20091.35 mm<jats:sup>2<\/jats:sup> vs. 7.35\u2009\u00b1\u20091.53 mm<jats:sup>2<\/jats:sup>, <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.002; and 101.19\u2009\u00b1\u200920.9 mm<jats:sup>3<\/jats:sup> vs. 118.51\u2009\u00b1\u200926.6 mm<jats:sup>3<\/jats:sup>, <jats:italic>P<\/jats:italic>\u2009=\u20090.001). Late lumen loss was 0.22\u2009\u00b1\u20090.30 mm at 6 months and 0.33\u2009\u00b1\u20090.44 mm at 18 months. No major adverse cardiac events occurred. At late follow\u2010up (18 months) the scaffold was not visualized by IVUS; therefore the evaluation was restricted to lumen and vessel at that time point.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>IVUS serial evaluation of the novel DESolve BRS showed an increase in the device dimensions between baseline and 6 months, with concomitant enlargement of lumen dimensions and effective suppression of neointimal proliferation. At 18 months, no footprint of the scaffold was detected and the initial lumen enlargement was sustained.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccd.27591","type":"journal-article","created":{"date-parts":[[2018,3,9]],"date-time":"2018-03-09T10:32:40Z","timestamp":1520591560000},"source":"Crossref","is-referenced-by-count":6,"title":["Serial intravascular ultrasound evaluation of the DESolve\u2122 novolimus\u2010eluting bioresorbable coronary scaffold system"],"prefix":"10.1002","volume":"92","author":[{"given":"Gentil","family":"Barreira","sequence":"first","affiliation":[{"name":"Department of Invasive Cardiology Instituto Dante Pazzanese de Cardiologia S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6286-3109","authenticated-orcid":false,"suffix":"Jr","given":"J. Ribamar","family":"Costa","sequence":"additional","affiliation":[{"name":"Department of Invasive Cardiology Instituto Dante Pazzanese de Cardiologia S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ricardo","family":"Costa","sequence":"additional","affiliation":[{"name":"Department of Invasive Cardiology Instituto Dante Pazzanese de Cardiologia S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rodolfo","family":"Staico","sequence":"additional","affiliation":[{"name":"Department of Invasive Cardiology Instituto Dante Pazzanese de Cardiologia S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel","family":"Chamie","sequence":"additional","affiliation":[{"name":"Department of Invasive Cardiology Instituto Dante Pazzanese de Cardiologia S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juliano R.","family":"Slhessarenko","sequence":"additional","affiliation":[{"name":"Department of Invasive Cardiology Instituto Dante Pazzanese de Cardiologia S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luiz Fernando","family":"Tanajura","sequence":"additional","affiliation":[{"name":"Department of Invasive Cardiology Instituto Dante Pazzanese de Cardiologia S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea","family":"Abizaid","sequence":"additional","affiliation":[{"name":"Department of Invasive Cardiology Instituto Dante Pazzanese de Cardiologia S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amanda","family":"Sousa","sequence":"additional","affiliation":[{"name":"Department of Invasive Cardiology Instituto Dante Pazzanese de Cardiologia S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexandre","family":"Abizaid","sequence":"additional","affiliation":[{"name":"Department of Invasive Cardiology Instituto Dante Pazzanese de Cardiologia S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,3,9]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.21037\/jtd.2016.05.80"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.116.021539"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2017.03.029"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(16)32050-5"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.4244\/EIJY14M07_11"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12471-017-1008-x"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.4244\/EIJY15M02_01"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2016.11.033"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2015.12.004"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.4244\/EIJY15M07_02"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(01)01175-5"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2013.07.007"},{"key":"e_1_2_7_14_1","first-page":"A10570","article-title":"ABSORB cohort a trial: Five year clinical and MSCT results of the ABSORB bioresorbable everolimus eluting vascular scaffold","volume":"124","author":"Onuma Y","year":"2011","journal-title":"Circulation"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.4244\/EIJ-D-17-00306"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehx155"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2017.04.011"}],"container-title":["Catheterization and Cardiovascular Interventions"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fccd.27591","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccd.27591","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,15]],"date-time":"2023-09-15T16:20:53Z","timestamp":1694794853000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccd.27591"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,3,9]]},"references-count":16,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2018,11,15]]}},"alternative-id":["10.1002\/ccd.27591"],"URL":"https:\/\/doi.org\/10.1002\/ccd.27591","archive":["Portico"],"relation":{},"ISSN":["1522-1946","1522-726X"],"issn-type":[{"value":"1522-1946","type":"print"},{"value":"1522-726X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,3,9]]}}}