{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,27]],"date-time":"2026-03-27T13:10:47Z","timestamp":1774617047727,"version":"3.50.1"},"reference-count":25,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2018,3,14]],"date-time":"2018-03-14T00:00:00Z","timestamp":1520985600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2018,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>This study aimed to assess the impact of pacemaker mode programming on clinical outcomes in patients with high\u2010degree atrioventricular conduction disturbance (AVCD) after transcatheter aortic valve implantation (TAVI).<\/jats:p><\/jats:sec><jats:sec><jats:title>Background<\/jats:title><jats:p>Although high\u2010degree AVCD after TAVI can receive pacemaker, recovery of the AVCD is often observed. Specific pacemaker algorithms (AAI\u2010DDD mode switch) are available which favor spontaneous atrioventricular conduction.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Of 1,621 consecutive multi\u2010center TAVI patients, 269 (16.4%) received pacemaker. We retrospectively included 91 patients with persistent high\u2010degree AVCD at hospital discharge. Pacemaker dependency was defined as absence, inadequate intrinsic ventricular rhythm, or ventricular pacing time\u2009&gt;\u200995% on pacemaker interrogation during follow\u2010up. Comparison of heart failure hospitalization and death between conventional DDD (cDDD) and other modes was examined (AAI\u2010DDD and VVI).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>During a mean follow\u2010up duration of 13 months, the pacemaker dependency rate was 52.8%. Patients with cDDD mode (N\u2009=\u200936: 40.0%) had significantly more pacemaker dependency. Multivariate analysis showed that cDDD mode was independently associated with pacemaker dependency (odds ratio\u2009=\u20093.63, <jats:italic>P<\/jats:italic>\u2009=\u20090.03). Moreover, cDDD patients had a significant higher incidence of heart failure hospitalization (Hospitalization: cDDD vs. others\u2009=\u200945.4% vs. 18.2%, <jats:italic>P<\/jats:italic>\u2009=\u20090.03) and had a higher incidence of mortality (Death: cDDD vs. the others\u2009=\u200927.0% vs. 4.4%, <jats:italic>P<\/jats:italic>\u2009=\u20090.06).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Up to half of patients implanted for high\u2010degree AVCD after TAVI had conduction recovery. Patients with cDDD programming at hospital discharge had more pacemaker dependency and a worse cardiac prognosis. Thus, pacemaker mode should be systematically set to promote spontaneous atrioventricular conduction in patients with pacemaker implantation after TAVI.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccd.27594","type":"journal-article","created":{"date-parts":[[2018,3,15]],"date-time":"2018-03-15T11:48:38Z","timestamp":1521114518000},"page":"1380-1386","source":"Crossref","is-referenced-by-count":9,"title":["Impact of pacemaker mode in patients with atrioventricular conduction disturbance after trans\u2010catheter aortic valve implantation"],"prefix":"10.1002","volume":"92","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3799-2256","authenticated-orcid":false,"given":"Masao","family":"Takahashi","sequence":"first","affiliation":[{"name":"University Hospital Henri Mondor, Department of Cardiology, 51 Avenue du Mar\u00e9chal de Lattre de Tassigny Cr\u00e9teil 94000 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Unit, 46 Rue Henri Huchard Paris 75018 France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marina","family":"Urena","sequence":"additional","affiliation":[{"name":"University Hospital Bichat, Cardiology Unit, 46 Rue Henri Huchard Paris 75018 France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicole","family":"Karam","sequence":"additional","affiliation":[{"name":"Cardiology Department European Hospital Georges Pompidou, 20 Rue Leblanc Paris 75015 France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eloi","family":"Marijon","sequence":"additional","affiliation":[{"name":"Cardiology Department European Hospital Georges Pompidou, 20 Rue Leblanc Paris 75015 France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vincent","family":"Algalarrondo","sequence":"additional","affiliation":[{"name":"University Hospital Antoine\u2010B\u00e9cl\u00e8re, Cardiology Unit, 157 Rue de la Porte de Trivaux Clamart 92140 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