{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,13]],"date-time":"2026-06-13T14:17:43Z","timestamp":1781360263716,"version":"3.54.1"},"reference-count":36,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2018,5,10]],"date-time":"2018-05-10T00:00:00Z","timestamp":1525910400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100008052","name":"Alfonso Martin Escudero Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008052","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2018,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To assess the clinical characteristics, management, and outcomes of patients diagnosed with infective endocarditis (IE) after edge\u2010to\u2010edge mitral valve repair with the MitraClip device.<\/jats:p><\/jats:sec><jats:sec><jats:title>Background<\/jats:title><jats:p>Transcatheter edge\u2010to\u2010edge mitral valve repair has emerged as an alternative to surgery in high\u2010risk patients. However, few data exist on IE following transcatheter mitral procedures.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Four electronic databases (PubMed, Google Scholar, Embase, and Cochrane Library) were searched for original published studies on IE after edge\u2010to\u2010edge transcatheter mitral valve repair from 2003 to 2017.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 10 publications describing 12 patients with definitive IE (median age 76 years, 55% men) were found. The mean logistic EuroSCORE\/EuroSCORE II were 41% and 45%, respectively. The IE episode occurred early (within 12 months post\u2010procedure) in nine patients (75%; within the first month in five patients). <jats:italic>Staphylococcus aureus<\/jats:italic> was the most frequent (60%) causal microorganism, and severe mitral regurgitation was present in all cases but one. Surgical mitral valve replacement (SMVR) was performed in most (67%) patients, and the mortality associated with the IE episode was high (42%).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>IE following transcatheter edge\u2010to\u2010edge mitral valve repair is a rare but life\u2010threatening complication, usually necessitating SMVR despite the high\u2010risk profile of the patients. These results highlight the importance of adequate preventive measures and a prompt diagnosis and treatment of this serious complication.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccd.27632","type":"journal-article","created":{"date-parts":[[2018,5,10]],"date-time":"2018-05-10T09:37:11Z","timestamp":1525945031000},"page":"583-591","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":25,"title":["Infective endocarditis following transcatheter edge\u2010to\u2010edge mitral valve repair: A systematic review"],"prefix":"10.1002","volume":"92","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3357-5834","authenticated-orcid":false,"given":"Lluis","family":"Asmarats","sequence":"first","affiliation":[{"name":"Quebec Heart and Lung Institute, Laval University Quebec City Quebec 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