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The aim of this study was to compare two stents that were previously frequently used in regard to long\u2010term risk of restenosis and stent thrombosis (ST).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods and results<\/jats:title><jats:p>We used data from the SCAAR registry. Consecutive procedures performed between 2004 and 2014 for stable angina, UA\/NSTEMI and STEMI were included. We compared two different stents: Cordis Cypher Select (C\u2010CS), and Boston Scientific Liberte (BS\u2010L), modeling data with multilevel Cox proportional\u2010hazards regression. The primary endpoint was time to first occurrence of either ST or restenosis. During the study period 2210 C\u2010CS and 6941 B\u2010SL were implanted in 5,314 patients. Mean follow\u2010up time was 2,288 days for C\u2010CS and 2,297 days for BS\u2010L. Treatment with C\u2010CS was associated with lower risk for restenosis or ST up to one year from index procedure (HR 0.41; 95% CI 0.32\u20100.52; <jats:italic>P<\/jats:italic>\u2009&lt;\u2009.001). However, after one year of follow\u2010up, risk was substantially higher in C\u2010CS (HR 2.81; 95% CI 2.25\u20103.50; <jats:italic>P<\/jats:italic>\u2009&lt;\u2009.001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Treatment with C\u2010CS was not associated with better outcome than BS\u2010L. Continuation of restenosis and ST long after the index procedure with C\u2010CS present a major concern for patient safety.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccd.27655","type":"journal-article","created":{"date-parts":[[2018,5,10]],"date-time":"2018-05-10T09:36:09Z","timestamp":1525944969000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Sustained risk of stent thrombosis and restenosis in first generation drug\u2010eluting Stents after One Decade of Follow\u2010up: A Report from the Swedish Coronary Angiography and Angioplasty Registry (SCAAR)"],"prefix":"10.1002","volume":"92","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9609-5360","authenticated-orcid":false,"given":"Sebastian","family":"V\u00f6lz","sequence":"first","affiliation":[{"name":"Department of Cardiology Sahlgrenska University Hospital  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