{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T02:10:18Z","timestamp":1740103818729,"version":"3.37.3"},"reference-count":5,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2018,8,2]],"date-time":"2018-08-02T00:00:00Z","timestamp":1533168000000},"content-version":"vor","delay-in-days":32,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2018,7]]},"abstract":"<jats:title>Key Points<\/jats:title><jats:p>\n<jats:list list-type=\"bullet\">\n<jats:list-item><jats:p>A meta\u2010analysis of five randomized controlled trials of closure of patent foramen ovale (PFO) versus medical therapy to prevent recurrent stroke shows a statistically significant absolute 2% decrease in recurrent stroke but no difference in death.<\/jats:p><\/jats:list-item>\n<jats:list-item><jats:p>Patients treated with PFO closure have an absolute 2% increase in the risk of atrial fibrillation, usually transient, after the procedure, as well as increased risk of procedural complications, which are usually minor.<\/jats:p><\/jats:list-item>\n<jats:list-item><jats:p>Guidelines on PFO closure were written before most data in this meta\u2010analysis were available. Those guidelines are now outdated.<\/jats:p><\/jats:list-item>\n<\/jats:list><\/jats:p>","DOI":"10.1002\/ccd.27699","type":"journal-article","created":{"date-parts":[[2018,8,7]],"date-time":"2018-08-07T04:22:52Z","timestamp":1533615772000},"page":"187-188","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["PFO closure: Where are the neurologists?"],"prefix":"10.1002","volume":"92","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4966-533X","authenticated-orcid":false,"given":"James C","family":"Blankenship","sequence":"first","affiliation":[{"name":"Heart Institute, Geisinger Health System Danville Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,8,2]]},"reference":[{"key":"e_1_2_2_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.27636"},{"key":"e_1_2_2_3_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.1000097"},{"key":"e_1_2_2_4_1","doi-asserted-by":"publisher","DOI":"10.1177\/1747493017743062"},{"key":"e_1_2_2_5_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000002961"},{"key":"e_1_2_2_6_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCINTERVENTIONS.116.003623"}],"container-title":["Catheterization and Cardiovascular Interventions"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fccd.27699","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccd.27699","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,17]],"date-time":"2023-09-17T10:12:14Z","timestamp":1694945534000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccd.27699"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,7]]},"references-count":5,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2018,7]]}},"alternative-id":["10.1002\/ccd.27699"],"URL":"https:\/\/doi.org\/10.1002\/ccd.27699","archive":["Portico"],"relation":{},"ISSN":["1522-1946","1522-726X"],"issn-type":[{"type":"print","value":"1522-1946"},{"type":"electronic","value":"1522-726X"}],"subject":[],"published":{"date-parts":[[2018,7]]},"assertion":[{"value":"2018-05-28","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-05-30","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-08-02","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}