{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T12:52:56Z","timestamp":1773147176320,"version":"3.50.1"},"reference-count":21,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2018,9,23]],"date-time":"2018-09-23T00:00:00Z","timestamp":1537660800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2018,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Prolonged dual anti\u2010platelet therapy (DAPT) is undesirable in certain patients. The biolimus\u2010A9 drug\u2010coated stent (BA9\u2010DCS) has a rapid drug\u2010elution profile allowing shortened DAPT.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The demographics, procedural data, and clinical outcomes for 505 patients presenting with an ACS to three UK centres and treated with a BA9\u2010DCS stent (PCI\u2010DCS) were collected, and compared to a consecutive ACS cohort of unselected patients treated in the same period with drug\u2010eluting stents (PCI\u2010DES).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>PCI\u2010DCS patients were older, more often female with hypertension, chronic kidney disease, severe LV dysfunction, and peripheral vascular disease more frequent than the PCI\u2010DES cohort. PCI\u2010DCS patients had a much higher Mehran bleed risk score (21.5\u2009\u00b1\u20097.7 vs. 15.9\u2009\u00b1\u20097.7, <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.0001). Baseline disease burden was greater in the PCI\u2010DCS cohort with more left main and three vessel disease. During PCI, more stents (1.91\u2009\u00b1\u20091.1 vs. 1.57\u2009\u00b1\u20090.94, <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.0001), total stent length (38.2\u2009\u00b1\u200920.8 vs. 31.4\u2009\u00b1\u200920.3, <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.0001) and longer stents (38.2\u2009\u00b1\u200920.8 vs. 31.4\u2009\u00b1\u200920.3 mm, <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.0001) were used in the PCI\u2010DCS cohort with rotational atherectomy also used more frequently. Physician\u2010recommended DAPT duration was 2.9\u2009\u00b1\u20093.9 months for PCI\u2010DCS patients and 11.3\u2009\u00b1\u20092.4 months for PCI\u2010DES patients (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.0001). At 12\u2010month follow\u2010up, definite stent thrombosis (0.6% vs. 1.1%) and TLR (3.2% vs. 2.7%) rates were similar between the two groups. After adjustment for baseline differences, there were no statistically significant differences in death and combined MACE rates at 12 months.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The outcomes of patients treated with polymer\u2010free BA9 drug\u2010coated stent who present with an ACS and who were deemed unsuitable for prolonged DAPT are encouraging. Further studies are warranted.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccd.27722","type":"journal-article","created":{"date-parts":[[2018,9,23]],"date-time":"2018-09-23T12:33:21Z","timestamp":1537706001000},"page":"1220-1228","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Twelve\u2010month outcomes of patients unsuitable for prolonged DAPT presenting with an acute coronary syndrome and treated with polymer\u2010free biolimus A9 drug\u2010coated stents"],"prefix":"10.1002","volume":"92","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1209-3534","authenticated-orcid":false,"given":"Tim","family":"Kinnaird","sequence":"first","affiliation":[{"name":"Department of Cardiology University Hospital of Wales  Cardiff United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fairoz","family":"Abdul","sequence":"additional","affiliation":[{"name":"Department of Cardiology University Hospital of Wales  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