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However, data regarding efficacy of this device and clinical outcomes are still limited.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods and results<\/jats:title><jats:p>From 1993 to 2015, among 97,779 patients from 9 European centres undergoing PCI, 224 patients had G3CP (0.23%), and 102 patients were managed with CS implantation (96 with PTFE, 6 with pericardium). Device oriented composite endpoint (DOCE), a composite of cardiac death, target lesion revascularization, and stent thrombosis (ST) in\u2010hospital and at long term follow\u2010up were evaluated. G3\u2010CP perforations were successfully sealed with CS in 88 patients (86.3%) with need of intraprocedural pericardiocentesis in one\u2010third of cases. Protamine as heparin reversal agent was administered in 36 (35%) of cases. The cumulative incidence of in\u2010hospital DOCE were 16.6% (17\/102): death 14.7%, TLR 2.9%, ST 3.9%. At long\u2010term follow\u2010up (mean 42\u2009\u00b1\u200938\u2009months), DOCE rates occurred in 19.7%: death 7.4%, TLR 11%, and ST 6.2%. Indication to Dual Antiplatelet Therapy (DAPT) was lifelong in 20% of cases, 1 to 6\u2009months in 22.5% and 12\u2010months in 57.5% without differences in long\u2010term DOCE before and after DAPT interruption (8.0 vs. 6.6%, respectively, <jats:italic>P<\/jats:italic>\u2009=\u20090.20).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Use of CS was successful in sealing grade 3 coronary artery perforations in the majority of cases. Beside the high rate of clinical events at short and long\u2010term, ST remains the leading cause of device failure.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccd.27789","type":"journal-article","created":{"date-parts":[[2018,9,23]],"date-time":"2018-09-23T12:31:21Z","timestamp":1537705881000},"page":"1247-1255","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Acute and long\u2010term outcomes after polytetrafluoroethylene or pericardium covered stenting for grade 3 coronary artery perforations: Insights from G3\u2010CAP registry"],"prefix":"10.1002","volume":"92","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4581-6700","authenticated-orcid":false,"given":"Marco","family":"Pavani","sequence":"first","affiliation":[{"name":"Division of Cardiology Citt\u00e0 della Salute e della Scienza di Torino  Turin 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