{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T13:25:44Z","timestamp":1762867544309,"version":"3.40.5"},"reference-count":24,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2018,9,24]],"date-time":"2018-09-24T00:00:00Z","timestamp":1537747200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100004826","name":"Beijing Natural Science Foundation","doi-asserted-by":"publisher","award":["7162160"],"award-info":[{"award-number":["7162160"]}],"id":[{"id":"10.13039\/501100004826","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81670283"],"award-info":[{"award-number":["81670283"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2018,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>Though successful transcatheter closure has been reported in secundum atrial septal defect (ASD) with deficient posterior\u2013inferior rim, it is still difficult to screen the appropriate candidates. Three\u2010dimensional printing (3DP) makes in vitro trial occlusion possible, and might provide a feasible method in the prediction of successful closure.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Thirty\u2010five consecutive ASD patients (10M\/25F, age, 47.7 \u00b1 11.8 years) with deficient posterior\u2013inferior rim (\u22643 mm) were referred for attempted transcatheter closure, and personalized heart model (elastic rubber) was produced based on end\u2010systolic MSCT images. The in vitro measurement and trial occlusion were performed for preoperative evaluation (in vitro successful\/unsuccessful group), and the results were compared with postoperative outcomes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Successful in vitro occlusion was achieved in 30 patients (7M\/23F), and the size of ASD was 27.1 \u00b1 4.4 mm. The posterior\u2013inferior rim was 0.95 \u00b1 1.22 mm (rim defect in 17 patients), and 12 patients were associated with aortic rim deficiency. The subsequent transcatheter closure was performed successfully in 29 patients, and the occluder\u2010diameter was identical to that of in vitro occlusion (35.0 \u00b1 4.4 mm). The follow\u2010up (1.4 \u00b1 0.58 years) showed no residual shunt and related\u2010complications. In unsuccessful in vitro group (<jats:italic>n<\/jats:italic> = 5), the range of rim deficiency was wider (<jats:italic>P<\/jats:italic> = 0.019) and the rim to inferior vena cava was shorter (4.60 \u00b1 2.07 mm vs. 10.71 \u00b1 5.28 mm, <jats:italic>P<\/jats:italic> = 0.016). Furthermore, transcatheter closure failed in all patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>In ASD with deficient posterior\u2013inferior rim, 3DP allows accurate determination of the size and surrounding rims of ASD. Based on personalized heart model, in vitro trial occlusion is an effective method to identify the appropriate candidates for transcatheter closure.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccd.27799","type":"journal-article","created":{"date-parts":[[2018,9,25]],"date-time":"2018-09-25T04:03:53Z","timestamp":1537848233000},"page":"1309-1314","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Three\u2010dimensional printing assisted transcatheter closure of atrial septal defect with deficient posterior\u2013inferior rim"],"prefix":"10.1002","volume":"92","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8864-5505","authenticated-orcid":false,"given":"Chaowu","family":"Yan","sequence":"first","affiliation":[{"name":"Department of Structural Heart Disease, Cardiovascular Institute and Fuwai Hospital, National Center for Cardiovascular Diseases Chinese Academy of Medical Sciences and Peking Union Medical College  Beijing 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