{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,10]],"date-time":"2026-08-10T03:12:05Z","timestamp":1786331525441,"version":"build-2736575974"},"reference-count":24,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2018,9,12]],"date-time":"2018-09-12T00:00:00Z","timestamp":1536710400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2019,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>The aim of this study was to assess the predictive value of PMA measurement for mortality.<\/jats:p><\/jats:sec><jats:sec><jats:title>Background<\/jats:title><jats:p>Current surgical risk stratification have limited predictive value in the transcatheter aortic valve implantation (TAVI) population. In TAVI workup, a CT scan is routinely performed but body composition is not analyzed. Psoas muscle area (PMA) reflects a patient's global muscle mass and accordingly PMA might serve as a quantifiable frailty measure.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Multi\u2010slice computed tomography scans (between 2010 and 2016) of 583 consecutive TAVI patients were reviewed. Patients were divided into equal sex\u2010specific tertiles (low, mid, and high) according to an indexed PMA. Hazard ratios (HR) and their confidence intervals (CI) were determined for cardiac and all\u2010cause mortality after TAVI.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Low iPMA was associated with cardiac and all\u2010cause mortality in females. One\u2010year adjusted cardiac mortality HR in females for mid\u2010iPMA and high\u2010iPMA were 0.14 [95%CI, 0.05\u20130.45] and 0.40 [95%CI, 0.15\u20130.97], respectively. Similar effects were observed for 30\u2010day and 2\u2010years cardiac and all\u2010cause mortality. In females, adding iPMA to surgical risk scores improved the predictive value for 1\u2010year mortality. C\u2010statistics changed from 0.63 [CI = 0.54\u20130.73] to 0.67 [CI: 0.58\u20130.75] for EuroSCORE II and from 0.67 [CI: 0.59\u20130.77] to 0.72 [CI: 0.63\u20130.80] for STS\u2010PROM.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Particularly in females, low iPMA is independently associated with an higher all\u2010cause and cardiac mortality. Prospective studies should confirm whether PMA or other body composition parameters should be extracted automatically from CT\u2010scans to include in clinical decision making and outcome prediction for TAVI.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccd.27823","type":"journal-article","created":{"date-parts":[[2018,9,12]],"date-time":"2018-09-12T16:20:11Z","timestamp":1536769211000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["CT determined psoas muscle area predicts mortality in women undergoing transcatheter aortic valve implantation"],"prefix":"10.1002","volume":"93","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8994-8946","authenticated-orcid":false,"given":"Martijn S.","family":"van Mourik","sequence":"first","affiliation":[{"name":"Amsterdam UMC University of Amsterdam, AMC Heartcenter, Amsterdam Cardiovascular Sciences  Amsterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yvonne C.","family":"Janmaat","sequence":"additional","affiliation":[{"name":"ACHIEVE \u2013 Centre of Applied Research Amsterdam University of Applied Sciences  Amsterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Floortje","family":"van Kesteren","sequence":"additional","affiliation":[{"name":"Amsterdam UMC University of Amsterdam, AMC Heartcenter, Amsterdam Cardiovascular Sciences  Amsterdam The Netherlands"},{"name":"Amsterdam UMC, University of Amsterdam, Department of Radiology  Amsterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeroen","family":"Vendrik","sequence":"additional","affiliation":[{"name":"Amsterdam UMC University of Amsterdam, AMC Heartcenter, Amsterdam Cardiovascular Sciences  Amsterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R. Nils","family":"Planken","sequence":"additional","affiliation":[{"name":"Amsterdam UMC, University of Amsterdam, Department of Radiology  Amsterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marieke J.","family":"Henstra","sequence":"additional","affiliation":[{"name":"Amsterdam UMC, University of Amsterdam, Department of Geriatrics  Amsterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2534-0752","authenticated-orcid":false,"given":"Juli\u00ebtte F.","family":"Velu","sequence":"additional","affiliation":[{"name":"Amsterdam UMC University of Amsterdam, AMC Heartcenter, Amsterdam Cardiovascular Sciences  Amsterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wieneke","family":"Vlastra","sequence":"additional","affiliation":[{"name":"Amsterdam UMC University of Amsterdam, AMC Heartcenter, Amsterdam Cardiovascular Sciences  Amsterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aeilko H.","family":"Zwinderman","sequence":"additional","affiliation":[{"name":"Department of Clinical Epidemiology, Biostatistics and Bioinformatics University of Amsterdam  Amsterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karel T.","family":"Koch","sequence":"additional","affiliation":[{"name":"Amsterdam UMC University of Amsterdam, AMC Heartcenter, Amsterdam Cardiovascular Sciences  Amsterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robbert J.","family":"de Winter","sequence":"additional","affiliation":[{"name":"Amsterdam UMC University of Amsterdam, AMC Heartcenter, Amsterdam Cardiovascular Sciences  Amsterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joanna J.","family":"Wykrzykowska","sequence":"additional","affiliation":[{"name":"Amsterdam UMC University of Amsterdam, AMC Heartcenter, Amsterdam Cardiovascular Sciences  Amsterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8666-7129","authenticated-orcid":false,"given":"Jan J.","family":"Piek","sequence":"additional","affiliation":[{"name":"Amsterdam UMC University of Amsterdam, AMC Heartcenter, Amsterdam Cardiovascular Sciences  Amsterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 P. 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