{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,12]],"date-time":"2025-09-12T17:37:53Z","timestamp":1757698673866,"version":"3.40.5"},"reference-count":25,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2018,10,2]],"date-time":"2018-10-02T00:00:00Z","timestamp":1538438400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2019,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>The aim of the present study was to compare the incidence of periprocedural complications and short\u2010term outcomes between the second\u2010generation recapturable 34\u2009mm Evolut\u2010R and its first\u2010generation 31\u2009mm predecessor.<\/jats:p><\/jats:sec><jats:sec><jats:title>Background<\/jats:title><jats:p>Although already in extensive clinical use in real world patients, the periprocedural complications and clinical outcomes of the new 34\u2009mm device have not been investigated yet.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Consecutive patients who had undergone transcatheter aortic valve implantation in two centers with either a 31\u2009mm CoreValve or a 34\u2009mm Evolut\u2010R device were retrospectively studied. Periprocedural complications of malpositioning, valve\u2010in\u2010valve implantation, conversion to full sternotomy or percutaneous coronary intervention and vascular complications were compared between the two groups. Short\u2010term outcomes at discharge were compared using Valve Academic Research Consortium (VARC\u20102) criteria.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The study group included 106 patients (35 Evolut\u2010R 34\u2009mm; 71 CoreValve 31\u2009mm). Significantly lower rates of valve\u2010in\u2010valve implantation were demonstrated for the 34\u2009mm group compared to the first\u2010generation device (0% vs. 11.9%, respectively, <jats:italic>P<\/jats:italic>\u2009=\u20090.036). All other periprocedural complications were similar between groups.<\/jats:p><jats:p>At discharge, the rates of new pacemaker implantation (5.7% vs. 26.8%, <jats:italic>P<\/jats:italic>\u2009=\u20090.037) and bleeding complications (2.9% vs. 19.6%, <jats:italic>P<\/jats:italic>\u2009=\u20090.025) were statistically significantly lower among the 34\u2009mm group. With regards to VARC\u20102 defined combined endpoints, rates of early safety were significantly improved among the 34\u2009mm group compared to 31\u2009mm group (0% vs. 27.9%, respectively, <jats:italic>P<\/jats:italic>\u2009=\u20090.004).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The recently introduced 34\u2009mm Evolut\u2010R seems to demonstrate an improved safety profile, as evidenced by the reduced bleeding rates, lower rates of valve\u2010in\u2010valve implantation and lower PPM rates compared to its 31\u2009mm predecessor.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccd.27862","type":"journal-article","created":{"date-parts":[[2018,10,3]],"date-time":"2018-10-03T05:29:35Z","timestamp":1538544575000},"page":"685-691","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Real\u2010world comparison of the new 34 mm self\u2010expandable transcatheter aortic prosthesis Evolut R to its 31 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