{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,20]],"date-time":"2026-06-20T22:43:55Z","timestamp":1781995435409,"version":"3.54.5"},"reference-count":24,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2018,11,30]],"date-time":"2018-11-30T00:00:00Z","timestamp":1543536000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100007914","name":"University of Texas Southwestern Medical Center","doi-asserted-by":"publisher","award":["UL1\u2010RR024982"],"award-info":[{"award-number":["UL1\u2010RR024982"]}],"id":[{"id":"10.13039\/100007914","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2019,2,15]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Use of atherectomy for the treatment of peripheral arterial disease (PAD) is increasing as an adjunctive treatment to either conventional or drug\u2010coated balloon angioplasty. There is limited data on atherectomy outcomes in below\u2010the\u2010knee (BTK) endovascular interventions.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Data from the multicenter Excellence in Peripheral Artery Disease (XLPAD) registry (NCT01904851) were analyzed to examine predictors of atherectomy use and its associated 1\u2010year patency rate. We analyzed 518 BTK procedures performed between January 2005 and December 2016.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Overall a total of 518 BTK procedures were treated in 430 patients, and 43% of interventions used atherectomy. African American patients were less likely (13% vs 25%; |standard residual|\u2009=\u20093.41) to be treated with atherectomy. Use of atherectomy was lower in chronic total occlusive (CTO) lesions (48% vs 58%; <jats:italic>P<\/jats:italic>\u2009=\u20090.02). There were no significant associations of baseline comorbidities, critical limb ischemia (CLI), ankle\u2010brachial index, number of BTK vessel run\u2010off, or vessel location with atherectomy use. Compared with patients without atherectomy, use of atherectomy was associated with lower incidence of repeat target limb intervention at 1 year after adjusting for age, CLI, in\u2010stent restenosis, heavy calcification, presence of diffuse disease, and CTO lesion traits (Hazard Ratio 0.41, 95% confidence interval 0.23\u20100.72; <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.01).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Compared with no atherectomy, use of atherectomy in BTK interventions is associated with lower rates of 1\u2010year repeat target limb revascularization. These findings require confirmation in prospective, randomized clinical studies.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccd.27897","type":"journal-article","created":{"date-parts":[[2018,11,30]],"date-time":"2018-11-30T09:01:10Z","timestamp":1543568470000},"page":"488-493","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["Atherectomy in below\u2010the\u2010knee endovascular interventions: One\u2010year outcomes from the XLPAD registry"],"prefix":"10.1002","volume":"93","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5567-1878","authenticated-orcid":false,"given":"Houman","family":"Khalili","sequence":"first","affiliation":[{"name":"Division of Cardiology, Department of Internal Medicine University of Texas Southwestern Medical Center  Dallas Texas"},{"name":"Veterans Affairs North Texas Health Care 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of Texas Southwestern Medical Center  Dallas Texas"},{"name":"Veterans Affairs North Texas Health Care System"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8279-0111","authenticated-orcid":false,"given":"Nicolas W.","family":"Shammas","sequence":"additional","affiliation":[{"name":"Midwest Cardiovascular Research Foundation  Davenport Iowa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1528-7625","authenticated-orcid":false,"given":"Anand","family":"Prasad","sequence":"additional","affiliation":[{"name":"University of Texas Health Science Center at San Antonio  San Antonio Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5043-784X","authenticated-orcid":false,"given":"Mazen","family":"Abu\u2010Fadel","sequence":"additional","affiliation":[{"name":"Oklahoma University Health Science Center  Oklahoma City 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