{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,20]],"date-time":"2026-03-20T08:07:06Z","timestamp":1773994026907,"version":"3.50.1"},"reference-count":5,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2018,11,1]],"date-time":"2018-11-01T00:00:00Z","timestamp":1541030400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2019,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background\/Objectives<\/jats:title><jats:p>Orbital atherectomy (OA) is routinely being used for plaque modification to facilitate percutaneous revascularization in patients with peripheral arterial disease (PAD) and arterial calcification. Guidewire fracture (GWF) during OA, though anecdotally described, has not been studied in a systematic manner. We conducted a review of the Manufacturer and User Facility Device Experience (MAUDE) database to study the reports of wire fracture and its management and consequences.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We queried the MAUDE database for all events involving the current generation of the OA device: \u201cDiamondback 360 Peripheral Orbital Atherectomy System\u201d, and \u201cStealth 360\u00b0 Orbital PAD System\u201d.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>We identified 62 reports of GWF during OA for PAD. The superficial femoral artery was the most commonly involved atherectomy site. The wire fractured at the soft tip in a majority of cases (68%). Embolized wire fragments were left in the patient in 36 cases (58%), retrieved percutaneously in 10 cases (16%), and trapped by a stent against the arterial wall in eight cases (13%). Lastly, eight patients (13%) underwent surgery for removal of the wire fragment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>This is the first published report to study the complication of GWF during peripheral OA. GWF is an uncommon but has significant procedural and clinical consequences. It results in a high rate of ancillary rescue procedures (including surgery) and is associated with a higher risk of arterial thrombosis and complications from wire retrieval attempts. The risk of wire fracture may be avoided with carefully adherence to the IFU.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccd.27933","type":"journal-article","created":{"date-parts":[[2018,11,2]],"date-time":"2018-11-02T04:35:32Z","timestamp":1541133332000},"page":"330-334","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Guidewire fracture during orbital atherectomy for peripheral artery disease: Insights from the Manufacturer and User Facility Device Experience database"],"prefix":"10.1002","volume":"93","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3251-2054","authenticated-orcid":false,"given":"Nicholas","family":"Isom","sequence":"first","affiliation":[{"name":"Department of Internal Medicine University of Kansas Medical Center  Kansas City Kansas"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Reza","family":"Masoomi","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Diseases University of Kansas Medical Center  Kansas City Kansas"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Axel","family":"Thors","sequence":"additional","affiliation":[{"name":"Department of Vascular Surgery University of Kansas Medical Center  Kansas City Kansas"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8768-1376","authenticated-orcid":false,"given":"Matthew","family":"Bunte","sequence":"additional","affiliation":[{"name":"Department of Cardiology St. Luke's Health Systems  Kansas City Missouri"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anand","family":"Prasad","sequence":"additional","affiliation":[{"name":"Department of Cardiology UT Health San Antonio  San Antonio Texas"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kirk","family":"Hance","sequence":"additional","affiliation":[{"name":"Department of Vascular Surgery University of Kansas Medical Center  Kansas City Kansas"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2440-9033","authenticated-orcid":false,"given":"Kamal","family":"Gupta","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Diseases University of Kansas Medical Center  Kansas City Kansas"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,11]]},"reference":[{"issue":"8","key":"e_1_2_8_2_1","first-page":"355","article-title":"The COMPLIANCE 360 degrees trial: A randomized, prospective, multicenter, pilot study comparing acute and long\u2010term results of orbital atherectomy to balloon angioplasty for calcified femoropopliteal disease","volume":"26","author":"Dattilo R","year":"2014","journal-title":"J Invasive Cardiol"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.25046"},{"key":"e_1_2_8_4_1","unstructured":"MAUDE: Manufacturer and User Facility Device Experience. Retrieved March 8 2018https:\/\/www.accessdata.fda.gov\/scripts\/cdrh\/cfdocs\/cfMAUDE\/search.CFM"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.carrev.2015.12.005"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.21898"}],"container-title":["Catheterization and Cardiovascular Interventions"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fccd.27933","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccd.27933","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ccd.27933","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccd.27933","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,14]],"date-time":"2023-09-14T21:17:08Z","timestamp":1694726228000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccd.27933"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,11]]},"references-count":5,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2019,2]]}},"alternative-id":["10.1002\/ccd.27933"],"URL":"https:\/\/doi.org\/10.1002\/ccd.27933","archive":["Portico"],"relation":{},"ISSN":["1522-1946","1522-726X"],"issn-type":[{"value":"1522-1946","type":"print"},{"value":"1522-726X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,11]]},"assertion":[{"value":"2018-04-20","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-09-23","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-11-01","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}