{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,19]],"date-time":"2025-09-19T10:44:37Z","timestamp":1758278677814,"version":"3.37.3"},"reference-count":40,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2018,11,25]],"date-time":"2018-11-25T00:00:00Z","timestamp":1543104000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100003669","name":"Research of Korea Centers for Disease Control and Prevention","doi-asserted-by":"crossref","award":["2016-ER6304-02"],"award-info":[{"award-number":["2016-ER6304-02"]}],"id":[{"id":"10.13039\/501100003669","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2019,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Limited studies focused on long\u2010term outcomes of statin therapy in patients with acute myocardial infarction (AMI) with or without dyslipidemia after percutaneous coronary intervention (PCI) in the era of new\u2010generation drug\u2010eluting stents (DES). We thought to investigate 2\u2010year clinical outcomes of statin therapy in these patients<jats:bold>.<\/jats:bold><\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A total of 18,137 eligible AMI patients (from the Korea AMI Registry [KAMIR]) were finally enrolled and divided into four groups according to the presence or absence of dyslipidemia and statin therapy (dyslipidemia+\/statin\u2212 [group A, 309 patients], dyslipidemia+\/statin+ [group B, 2094 patients], dyslipidemia\u2212\/statin\u2013 [group C, 672 patients], dyslipidemia\u2212\/statin+ [group D, 15062 patients]). The primary outcome was major adverse cardiac event (MACE) defined as all\u2010cause death, myocardial infarction (MI) and revascularization.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>During the 2\u2010year follow\u2010up period, the cumulative incidence of MACE in the group A was higher than the group B (adjusted hazard ratio [HR], 2.207; 95% confidence interval (CI), 1.098\u20133.743; <jats:italic>p<\/jats:italic>\u2009=\u2009.024) and the group D (adjusted HR, 2.110; 95% CI, 1.240\u20133.593, <jats:italic>p<\/jats:italic>\u2009=\u2009.006). This significantly increased incidence of MACE caused by the higher cumulative incidences of all\u2010cause death and cardiac death (CD) in the group A compared with groups B and D. However, the cumulative incidences of MI and revascularization were not significantly different among these four groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Statin therapy demonstrated significantly reduced incidences of MACE, all\u2010cause death and CD compared with non\u2010users after PCI in AMI patients with or without dyslipidemia during 2\u2010year follow\u2010up period in the era of new\u2010generation DES.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccd.27985","type":"journal-article","created":{"date-parts":[[2018,11,26]],"date-time":"2018-11-26T07:49:08Z","timestamp":1543218548000},"page":"1264-1275","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Two\u2010year outcomes of statin therapy in patients with acute myocardial infarction with or without dyslipidemia after percutaneous coronary intervention in the era of new\u2010generation drug\u2010eluting stents within Korean population: Data from the Korea Acute Myocardial Infarction Registry"],"prefix":"10.1002","volume":"93","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9669-3598","authenticated-orcid":false,"given":"Yong Hoon","family":"Kim","sequence":"first","affiliation":[{"name":"Division of Cardiology, Department of Internal Medicine Kangwon National University School of Medicine  Chuncheon South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9990-6843","authenticated-orcid":false,"given":"Ae\u2010Young","family":"Her","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department of Internal Medicine Kangwon National University School of Medicine  Chuncheon South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Myung Ho","family":"Jeong","sequence":"additional","affiliation":[{"name":"Chonnam National University Hospital  Gwangju South 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