{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,12]],"date-time":"2025-11-12T14:00:21Z","timestamp":1762956021954,"version":"3.40.5"},"reference-count":16,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2018,12,12]],"date-time":"2018-12-12T00:00:00Z","timestamp":1544572800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2019,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To assess the impact of WATCHMAN\u2122 on quality of life (QoL) in octogenarians and nonagenarians.<\/jats:p><\/jats:sec><jats:sec><jats:title>Background<\/jats:title><jats:p>QoL after WATCHMAN\u2122 device in the elderly remains unknown.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This is a prospective and retrospective cohort study of patients that underwent WATCHMAN\u2122 implantation in a tertiary cardiovascular center from April 1, 2015 to September 27, 2017. The primary outcome was a prospective assessment of QoL via the SF\u201012v2 Health Survey (SF\u201012v2) in those aged \u226580 and \u226590\u2009years. Secondary outcomes include major bleeding, stroke, vascular complications, pericardial effusion, device related thrombus (DRT), prolonged length of stay (LOS), acute kidney injury (AKI), and recurrent hospitalizations.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>This cohort of 151 patients included 48\/151 (32%) females with a mean age of 80\u2009\u00b1\u20097.7\u2009years. Mean CHA<jats:sub>2<\/jats:sub>DS<jats:sub>2<\/jats:sub>\u2010VASc was 4.38\u2009\u00b1\u20091.36 and mean HAS\u2010BLED was 3.27\u2009\u00b1\u20091.17. Octogenarians 65\/81(80%) and nonagenarians 16\/81(20%) comprised 81\/151(54%) of patients (mean age 86\u2009\u00b1\u20094.3\u2009years) from which 36\/65 (55%) octogenarians and 10\/16 (63%) nonagenarians completed SF\u201012v2 evaluation at 22\u2009\u00b1\u200910 and 30\u2009\u00b1\u200910\u2010months. Octogenarians demonstrated enhanced physical component scores (PCS), and nonagenarians equal PCS versus the age\u2010adjusted norm (45.43\u2009\u00b1\u20099.84 versus 38.68\u2009\u00b1\u200911.04, <jats:italic>P<\/jats:italic>\u2009=\u20090.0003, and 41.26\u2009\u00b1\u200912.36 versus 38.68\u2009\u00b1\u200911.04, <jats:italic>P<\/jats:italic>\u2009=\u20090.6463, respectively). The mental component scores (MCS) of octogenarians and nonagenarians remained comparable (51.80\u2009\u00b1\u20099.56 and 48.97\u2009\u00b1\u20099.92 versus 50.06\u2009\u00b1\u200910.94, respectively, <jats:italic>P<\/jats:italic>\u2009=\u20090.4659). No stroke, vascular complications, pericardial effusions, or readmissions related to WATCHMAN\u2122 occurred. No difference among patients &lt;80, \u226580, and \u226590\u2009years was found in major bleeding events, DRT, prolonged LOS, or AKI (<jats:italic>P<\/jats:italic>\u2009=\u20090.0569, 0.116, 0.498, and 0.795, respectively).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Octogenarians and nonagenarians experience favorable long\u2010term QoL after WATCHMAN\u2122, with acceptable bleeding risk and low incidence of procedure\u2010related complications.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccd.28020","type":"journal-article","created":{"date-parts":[[2018,12,12]],"date-time":"2018-12-12T11:44:35Z","timestamp":1544615075000},"page":"1138-1145","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Long\u2010term quality of life in octogenarians and nonagenarians with nonvalvular atrial fibrillation following WATCHMAN\u2122 device implantation"],"prefix":"10.1002","volume":"93","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8027-7063","authenticated-orcid":false,"given":"Fergie J.","family":"Ramos Tuarez","sequence":"first","affiliation":[{"name":"University of Miami\u2010JFK Medical Center Palm Beach Regional GME Consortium  Atlantis Florida"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1920-9392","authenticated-orcid":false,"given":"Jesus E.","family":"Pino","sequence":"additional","affiliation":[{"name":"University of Miami\u2010JFK Medical Center Palm Beach Regional GME Consortium  Atlantis Florida"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4696-8645","authenticated-orcid":false,"given":"Abdulah","family":"Alrifai","sequence":"additional","affiliation":[{"name":"University of Miami\u2010JFK Medical Center Palm Beach Regional GME Consortium  Atlantis Florida"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohamad","family":"Kabach","sequence":"additional","affiliation":[{"name":"University of Miami\u2010JFK Medical Center Palm Beach Regional GME Consortium  Atlantis Florida"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elie","family":"Donath","sequence":"additional","affiliation":[{"name":"University of Miami\u2010JFK Medical Center Palm Beach Regional GME Consortium  Atlantis Florida"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jorge","family":"Saona","sequence":"additional","affiliation":[{"name":"University of Miami\u2010JFK Medical Center Palm Beach Regional GME Consortium  Atlantis Florida"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julio Grajeda","family":"Chavez","sequence":"additional","affiliation":[{"name":"University of Miami\u2010JFK Medical Center Palm Beach Regional GME Consortium  Atlantis Florida"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ximena Torres","family":"Diaz","sequence":"additional","affiliation":[{"name":"University of Miami\u2010JFK Medical Center Palm Beach Regional GME Consortium  Atlantis Florida"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcelo","family":"Jimenez","sequence":"additional","affiliation":[{"name":"University of Miami\u2010JFK Medical Center Palm Beach Regional GME Consortium  Atlantis Florida"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert","family":"Chait","sequence":"additional","affiliation":[{"name":"University of Miami\u2010JFK Medical Center Palm Beach Regional GME Consortium  Atlantis Florida"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,12,12]]},"reference":[{"key":"e_1_2_9_2_1","first-page":"11","article-title":"Mechanism and management of thromboembolism in AF","volume":"7","author":"Violi F","year":"2014","journal-title":"J Atr Fibrill"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-146-12-200706190-00007"},{"key":"e_1_2_9_4_1","unstructured":"FrederickAM HughC CliffordJK JosephPD DavidJS ZoltanGT. Left atrial appendage occlusion device societal overview. Page 1. 2015 ACC\/HRS\/SCAI left atrial appendage occlusion device societal overview."},{"key":"e_1_2_9_5_1","first-page":"417","article-title":"Safety of percutaneous left atrial appendage closure: Results from the Watchman left atrial appendage system for embolic protection in patients with AF (PROTECT AF) clinical trial and the continued access registry 2011","volume":"4","author":"Reddy VY","year":"2017","journal-title":"Circulation"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.anr.2015.10.001"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005650-199603000-00003"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.2215\/CJN.07231009"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005650-199303000-00006"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0895-4356(98)00083-3"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11136-015-0959-x"},{"volume-title":"SF\u201012: How to Score the SF\u201012 Physical and Mental Health Summary Scales","year":"1995","author":"Ware JE","key":"e_1_2_9_12_1"},{"key":"e_1_2_9_13_1","first-page":"1171","article-title":"Cross\u2010validation of item selection and scoring for the SF\u201012 health survey in nine countries: Results from the IQOLA Project","volume":"51","author":"Barbara G","year":"1998","journal-title":"JCE"},{"key":"e_1_2_9_14_1","doi-asserted-by":"crossref","first-page":"1790","DOI":"10.1016\/j.jacc.2013.01.061","article-title":"Quality of life assessment in the randomized PROTECT AF (percutaneous closure of the left atrial appendage versus warfarin therapy for prevention of stroke in patients with atrial fibrillation) trial of patients at risk for stroke with nonvalvular atrial fibrillation","volume":"61","author":"Olusun A","year":"2013","journal-title":"JACC"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/MBC.0000000000000186"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.4022\/jafib.1729"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.1991.00400100032005"}],"container-title":["Catheterization and Cardiovascular Interventions"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccd.28020","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ccd.28020","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccd.28020","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,8]],"date-time":"2023-09-08T02:02:43Z","timestamp":1694138563000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccd.28020"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,12,12]]},"references-count":16,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2019,5]]}},"alternative-id":["10.1002\/ccd.28020"],"URL":"https:\/\/doi.org\/10.1002\/ccd.28020","archive":["Portico"],"relation":{},"ISSN":["1522-1946","1522-726X"],"issn-type":[{"type":"print","value":"1522-1946"},{"type":"electronic","value":"1522-726X"}],"subject":[],"published":{"date-parts":[[2018,12,12]]},"assertion":[{"value":"2018-06-06","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-11-19","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-12-12","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}