{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,12]],"date-time":"2025-11-12T03:26:11Z","timestamp":1762917971680,"version":"3.40.5"},"reference-count":31,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2018,12,19]],"date-time":"2018-12-19T00:00:00Z","timestamp":1545177600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2019,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To compare the in\u2010hospital outcomes of transcatheter aortic valve replacement (TAVR) versus surgical aortic valve replacement (SAVR) in nonagenarians.<\/jats:p><\/jats:sec><jats:sec><jats:title>Background<\/jats:title><jats:p>Data comparing the outcomes of TAVR versus SAVR in nonagenarians are limited.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Using the National Inpatient Sample years 2012\u20132014, hospitalization data were retrieved for subjects aged \u226590\u2009years who underwent TAVR or SAVR for severe aortic stenosis. The incidence of in\u2010hospital mortality and peri\u2010procedural outcomes were compared using unadjusted, multivariate logistic regression, and propensity score matched analyses.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The final cohort included 6,680 records of nonagenarians undergoing aortic valve replacement, among which 5,840 (87.4%) underwent TAVR. There was no difference in the incidence of in\u2010hospital mortality between both groups in the unadjusted (5.8% versus 6.0% <jats:italic>P<\/jats:italic>\u2009=\u20090.95), multivariate (odds ratio [OR] 0.78, 95% confidence interval [CI] 0.35\u20131.74), and propensity score matched (OR 1.07, 95% CI 0.75\u20131.51) analyses. In the propensity\u2010matched analysis, TAVR was associated with a lower incidence of acute kidney injury (OR 0.58, 95% CI 0.47\u20130.72), post\u2010operative blood transfusion (OR 0.51, 95% CI 0.43\u20130.61), a higher likelihood of discharge to home (OR 4.71, 95% 3.44\u20135.06), and a similar incidence of pacemaker placement (OR 1.16, 95% 0.89\u20131.53) and stroke (OR 1.34, 0.90\u20131.99).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>In this nationwide analysis, TAVR was associated with an overall similar incidence of in\u2010hospital mortality and less morbidity compared with SAVR. These findings suggest that TAVR is effective and safe in nonagenarians.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccd.28050","type":"journal-article","created":{"date-parts":[[2018,12,20]],"date-time":"2018-12-20T07:15:16Z","timestamp":1545290116000},"page":"989-995","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["In\u2010hospital outcomes of transcatheter versus surgical aortic valve replacement for nonagenarians"],"prefix":"10.1002","volume":"93","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9853-7591","authenticated-orcid":false,"given":"Islam Y.","family":"Elgendy","sequence":"first","affiliation":[{"name":"Division of Cardiovascular Medicine, Department of Medicine University of Florida  Gainesville Florida"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2459-5195","authenticated-orcid":false,"given":"Ahmed N.","family":"Mahmoud","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Medicine, Department of Medicine University of Florida  Gainesville Florida"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ayman","family":"Elbadawi","sequence":"additional","affiliation":[{"name":"Department of Medicine Rochester General Hospital  Rochester New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akram Y.","family":"Elgendy","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Medicine, Department of Medicine University of Florida  Gainesville Florida"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohamed A.","family":"Omer","sequence":"additional","affiliation":[{"name":"Saint Luke's Mid America Heart Institute\/University of Missouri\u2013Kansas City  Kansas City Missouri"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3176-6677","authenticated-orcid":false,"given":"Michael","family":"Megaly","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Medicine Minneapolis Heart Institute, Abbot Northwestern Hospital  Minneapolis Minnesota"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4574-4287","authenticated-orcid":false,"given":"Mohammad K.","family":"Mojadidi","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Medicine, Department of Medicine Virginia Commonwealth University  Richmond Virginia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hani","family":"Jneid","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Medicine Baylor College of Medicine  Houston Texas"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,12,19]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2016.11.033"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1008232"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1400590"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1514616"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1700456"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamcollsurg.2006.08.026"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2016.01.055"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2014.06.015"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2015.02.045"},{"volume-title":"The Next Four Decades: The Older Population in the United States 2010 to 2050","year":"2010","author":"Vincent GK","key":"e_1_2_7_11_1"},{"key":"e_1_2_7_12_1","unstructured":"NIS HCUP Nationwide Inpatient Sample. 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