{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T13:55:30Z","timestamp":1791986130208,"version":"4.4.0"},"reference-count":34,"publisher":"Wiley","issue":"S1","license":[{"start":{"date-parts":[[2019,1,13]],"date-time":"2019-01-13T00:00:00Z","timestamp":1547337600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100003345","name":"Chinese Academy of Meteorological Sciences","doi-asserted-by":"publisher","award":["2016\u2010I2M\u20101\u2010009"],"award-info":[{"award-number":["2016\u2010I2M\u20101\u2010009"]}],"id":[{"id":"10.13039\/501100003345","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004572","name":"National Health and Family Planning Commission of the People's Republic of China","doi-asserted-by":"publisher","award":["201402001"],"award-info":[{"award-number":["201402001"]}],"id":[{"id":"10.13039\/501100004572","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2019,2,15]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To explore the relationship between inhospital outcomes and different estimated glomerular filtration rates (eGFRs) and determine an optimal eGFR cutoff value for predicting risk in patients with renal insufficiency (RI).<\/jats:p><\/jats:sec><jats:sec><jats:title>Background<\/jats:title><jats:p>RI is a predictor of poor prognosis in patients with myocardial infarction undergoing primary percutaneous coronary intervention (PCI). However, the cutoff value of the eGFR is questionable.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We included 10,240 patients with ST segment elevation myocardial infarction (STEMI) undergoing primary PCI from January 2013 to January 2016 who participated in the China Acute Myocardial Infarction registry. RI was defined as eGFR &lt;60\u2009mL\/min\/1.73\u2009m<jats:sup>2<\/jats:sup>. Patients were stratified into five eGFR groups to determine the optimal cutoff value: &lt;30, 30\u201345, 45\u201360, 60\u201390, and\u2009&gt;\u200990\u2009mL\/min\/1.73\u2009m<jats:sup>2<\/jats:sup>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Overall, 1,112 (10.9%) patients had eGFR &lt;60\u2009mL\/min\/1.73\u2009m<jats:sup>2<\/jats:sup>. Patients with eGFR&lt;60\u2009mL\/min\/1.73\u2009m<jats:sup>2<\/jats:sup> had a significantly higher incidence of all\u2010cause death and major adverse cardiovascular and cerebrovascular events (MACCEs) than those with eGFR &gt;60\u2009mL\/min\/1.73\u2009m<jats:sup>2<\/jats:sup>. Occurrence trend test analysis revealed that the incidence of inhospital all\u2010cause death and MACCEs increased as the eGFR decreased. In logistic multivariate\u2010adjusted analysis, eGFR &lt;45\u2009mL\/min\/1.73\u2009m<jats:sup>2<\/jats:sup> was associated with a higher incidence of all\u2010cause death and MACCEs than eGFR &gt;90\u2009mL\/min\/1.73\u2009m<jats:sup>2<\/jats:sup>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>RI is common among patients with STEMI undergoing primary PCI. A low eGFR is an indicator of worse inhospital prognosis. We suggest an eGFR cutoff value of 45\u2009mL\/min\/1.73\u2009m<jats:sup>2<\/jats:sup> to predict inhospital deaths and MACCEs.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccd.28060","type":"journal-article","created":{"date-parts":[[2019,1,14]],"date-time":"2019-01-14T05:44:28Z","timestamp":1547444668000},"page":"793-799","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Impact of baseline estimated glomerular filtration rate on inhospital outcomes of patients with ST\u2010elevation myocardial infarction undergoing primary percutaneous coronary intervention: A China acute myocardial infarction registry study"],"prefix":"10.1002","volume":"93","author":[{"given":"Sida","family":"Jia","sequence":"first","affiliation":[{"name":"Department of Cardiology, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases Chinese Academy of Medical Sciences and Peking Union Medical 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