{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,8]],"date-time":"2026-04-08T09:30:59Z","timestamp":1775640659226,"version":"3.50.1"},"reference-count":43,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2019,2,21]],"date-time":"2019-02-21T00:00:00Z","timestamp":1550707200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100001316","name":"Abbott Laboratories","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100001316","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004325","name":"AstraZeneca","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004325","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004374","name":"Medtronic","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004374","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004319","name":"Pfizer","doi-asserted-by":"publisher","award":["10458620"],"award-info":[{"award-number":["10458620"]}],"id":[{"id":"10.13039\/100004319","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100011725","name":"Servier","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100011725","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007054","name":"MSD","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007054","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2019,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To evaluate the clinical characteristics and outcomes of patients with peripheral vascular disease (PVD) undergoing percutaneous coronary intervention (PCI) in a contemporary setting, and to determine whether use of drug\u2010eluting stents (DESs) improves outcomes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Background<\/jats:title><jats:p>PVD was an independent risk factor for adverse outcomes following PCI in the bare\u2010metal stent (BMS) era. It is not known whether outcomes in these patients have improved with advances in interventional techniques and stent technology, as they have for the general population.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Eighteen thousand three hundred and eighty patients undergoing PCI from an Australian registry between 2005 and 2013 were studied. Clinical and procedural data, 30\u2010day and 12\u2010month outcomes were compared in those with and without a reported history of PVD. Outcomes were also compared between patients with PVD who received DES and those who received BMS. Long\u2010term mortality was compared using Australian National Death Index (NDI) linkage.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Patients with PVD (<jats:italic>n<\/jats:italic>\u2009=\u20091,251, 6.8%) were older and had more prevalent diabetes, hypertension, cerebrovascular disease, heart failure, renal impairment, ostial lesions, left main, and multi\u2010vessel disease (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001). Patients with PVD had significantly higher rates of major adverse cardiovascular events (MACEs) compared with those without PVD, in\u2010hospital (5.7% vs. 4.1%, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.008), at 30\u2010days (8.6% vs. 5.8%, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001) and at 12\u2010months (24.6% vs. 13.2%, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001). At 4.9\u2009\u00b1\u20092.6 years follow\u2010up, there was significantly greater mortality in the PVD group. PVD patients who received DES experienced significantly less MACE than PVD patients treated with BMS at 30\u2010days (4.8 vs. 10.1%, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001) and 12\u2010months (19.4 vs. 26.4%, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.005).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>PVD is an independent predictor of adverse outcomes in patients undergoing PCI. PVD patient who received DES had improved outcomes compared with those receiving BMS.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccd.28145","type":"journal-article","created":{"date-parts":[[2019,2,21]],"date-time":"2019-02-21T11:22:28Z","timestamp":1550748148000},"page":"588-597","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Outcomes in patients with peripheral vascular disease following percutaneous coronary intervention"],"prefix":"10.1002","volume":"94","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8910-3863","authenticated-orcid":false,"given":"John","family":"Ramzy","sequence":"first","affiliation":[{"name":"Department of Cardiology The Royal Melbourne Hospital  Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nick","family":"Andrianopoulos","sequence":"additional","affiliation":[{"name":"Centre of Cardiovascular Research and Education in Therapeutics (CCRE), Department of Epidemiology and Preventative Medicine Monash University  Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Louise","family":"Roberts","sequence":"additional","affiliation":[{"name":"Department of Cardiology Box Hill Hospital  Melbourne Victoria Australia"},{"name":"Eastern Health Clinical School Monash University  Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephen J.","family":"Duffy","sequence":"additional","affiliation":[{"name":"Centre of Cardiovascular Research and Education in Therapeutics (CCRE), Department of Epidemiology and Preventative Medicine Monash University  Melbourne Victoria Australia"},{"name":"Department of Cardiovascular Medicine Alfred Hospital  Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Clark","sequence":"additional","affiliation":[{"name":"Department of Cardiology Austin Hospital  Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrew W.","family":"Teh","sequence":"additional","affiliation":[{"name":"Department of Cardiology Box Hill Hospital  Melbourne Victoria Australia"},{"name":"Eastern Health Clinical School Monash University  Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrew E.","family":"Ajani","sequence":"additional","affiliation":[{"name":"Department of Cardiology The Royal Melbourne Hospital  Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christopher M.","family":"Reid","sequence":"additional","affiliation":[{"name":"Centre of Cardiovascular Research and Education in Therapeutics (CCRE), Department of Epidemiology and Preventative Medicine Monash University  Melbourne Victoria Australia"},{"name":"School of Public Health Curtin University  Perth Western Australia Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Angela","family":"Brennan","sequence":"additional","affiliation":[{"name":"Centre of Cardiovascular Research and Education in Therapeutics (CCRE), Department of Epidemiology and Preventative Medicine Monash University  Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Melanie","family":"Freeman","sequence":"additional","affiliation":[{"name":"Department of Cardiology Box Hill Hospital  Melbourne Victoria Australia"},{"name":"Eastern Health Clinical School Monash University  Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"On behalf of the Melbourne Interventional Group (MIG)","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,2,21]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(13)61249-0"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehl114"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.286.11.1317"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(00)00768-3"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.102.24.2945"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2010.11.019"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0025-6196(11)62592-5"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCINTERVENTIONS.108.847459"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(99)00262-4"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9149(03)00726-4"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.atherosclerosis.2013.04.005"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2004.03.010"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2006.03.067"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1583\/1545-1550(2004)011<0060:IOSPAD>2.0.CO;2"},{"key":"e_1_2_7_16_1","first-page":"132","article-title":"Impact of peripheral vascular disease on short\u2010 and long\u2010term outcomes in patients undergoing non\u2010emergent percutaneous coronary intervention in the drug\u2010eluting stent era","volume":"25","author":"Midwall S","year":"2013","journal-title":"J Invasive Cardiol"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(01)01702-8"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hlc.2005.08.001"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hlc.2010.10.002"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.5694\/j.1326-5377.2010.tb03499.x"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.5694\/j.1326-5377.2004.tb05911.x"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hlc.2010.11.001"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa067722"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.5694\/j.1326-5377.2006.tb00611.x"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2011.05.024"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2009.12.043"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2005.04.037"},{"key":"e_1_2_7_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2009.01.050"},{"key":"e_1_2_7_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(13)61170-8"},{"key":"e_1_2_7_30_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.21087"},{"key":"e_1_2_7_31_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2013.1556"},{"key":"e_1_2_7_32_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.110.002683"},{"key":"e_1_2_7_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9149(03)00972-X"},{"key":"e_1_2_7_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2012.05.010"},{"key":"e_1_2_7_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2007.06.026"},{"key":"e_1_2_7_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2007.10.040"},{"key":"e_1_2_7_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hlc.2015.06.826"},{"key":"e_1_2_7_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2011.07.021"},{"key":"e_1_2_7_39_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2005-04-1710"},{"key":"e_1_2_7_40_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.107.694273"},{"key":"e_1_2_7_41_1","doi-asserted-by":"publisher","DOI":"10.1002\/clc.20231"},{"key":"e_1_2_7_42_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.109.877092"},{"key":"e_1_2_7_43_1","first-page":"CD001800","article-title":"Exercise\u2010based cardiac rehabilitation for coronary heart disease","author":"Heran BS","year":"2011","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_7_44_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2011.08.023"}],"container-title":["Catheterization and Cardiovascular Interventions"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fccd.28145","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccd.28145","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ccd.28145","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccd.28145","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,8]],"date-time":"2023-09-08T17:15:11Z","timestamp":1694193311000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccd.28145"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,2,21]]},"references-count":43,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2019,10]]}},"alternative-id":["10.1002\/ccd.28145"],"URL":"https:\/\/doi.org\/10.1002\/ccd.28145","archive":["Portico"],"relation":{},"ISSN":["1522-1946","1522-726X"],"issn-type":[{"value":"1522-1946","type":"print"},{"value":"1522-726X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,2,21]]},"assertion":[{"value":"2018-10-21","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-01-28","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-02-21","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}