{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T22:32:38Z","timestamp":1772231558165,"version":"3.50.1"},"reference-count":25,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2019,5,27]],"date-time":"2019-05-27T00:00:00Z","timestamp":1558915200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100003669","name":"Research of Korea Centers for Disease Control and Prevention","doi-asserted-by":"crossref","award":["2013-E63005-02"],"award-info":[{"award-number":["2013-E63005-02"]}],"id":[{"id":"10.13039\/501100003669","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2020,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Few data are available for current usage patterns of intravascular modalities such as intravascular ultrasound (IVUS), optical coherence tomography (OCT), and fractional flow reserve (FFR) in acute myocardial infarction (AMI). Moreover, patient and procedural\u2010based outcomes related to intravascular modality guidance compared to angiography guidance have not been fully investigated yet.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We examined 11,731 patients who underwent percutaneous coronary intervention (PCI) from the Korea AMI Registry\u2013National Institute of Health database. Patient\u2010oriented composite endpoint (POCE) was defined as all\u2010cause death, any infarction, and any revascularization. Device\u2010oriented composite endpoint (DOCE) was defined as cardiac death, target\u2010vessel reinfarction, and target\u2010lesion revascularization.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Overall, intravascular modalities were utilized in 2,659 (22.7%) patients including 2,333 (19.9%) IVUS, 277 (2.4%) OCT, and 157 (1.3%) FFR. In the unmatched cohort, POCE (5.4 vs. 8.5%; adjusted hazard ratio (HR) 0.75; 95% confidence interval (CI) 0.61\u20130.93; <jats:italic>p<\/jats:italic> = .008) and DOCE (4.6 vs. 7.4%; adjusted HR 0.77; 95% CI 0.61\u20130.97; <jats:italic>p<\/jats:italic> = .028) were significantly lower in intravascular modality\u2010guided PCI compared with angiography\u2010guided PCI. In the propensity\u2010score\u2010matched cohorts, POCE (5.9 vs. 7.7%; HR 0.74; 95% CI 0.60\u20130.92; <jats:italic>p<\/jats:italic> = .006) and DOCE (5.0 vs. 6.8%; HR 0.72; 95% CI 0.57\u20130.90; <jats:italic>p<\/jats:italic> = .004) were significantly lower in intravascular modality guidance compared with angiography guidance. The difference was mainly driven by reduced all\u2010cause mortality (4.4 vs. 7.0%; <jats:italic>p<\/jats:italic>\u2009&lt;\u2009.001) and cardiac mortality (3.3 vs. 5.2%; <jats:italic>p<\/jats:italic>\u2009&lt;\u2009.001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>In this large\u2010scale AMI registry, intravascular modality guidance was associated with an improving clinical outcome in selected high\u2010risk patients.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccd.28359","type":"journal-article","created":{"date-parts":[[2019,5,27]],"date-time":"2019-05-27T12:54:49Z","timestamp":1558961689000},"page":"696-703","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Intravascular modality\u2010guided versus angiography\u2010guided percutaneous coronary intervention in acute myocardial infarction"],"prefix":"10.1002","volume":"95","author":[{"given":"Namkyun","family":"Kim","sequence":"first","affiliation":[{"name":"Department of Internal Medicine Kyungpook National University Hospital  Daegu Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7101-0236","authenticated-orcid":false,"given":"Jang Hoon","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Kyungpook National University Hospital  Daegu Republic of Korea"},{"name":"School of Medicine Kyungpook National University  Daegu Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Se Yong","family":"Jang","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Kyungpook National University Hospital  Daegu Republic of Korea"},{"name":"School of Medicine Kyungpook National University  Daegu Republic of 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Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0847-5329","authenticated-orcid":false,"given":"Hyo\u2010Soo","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Seoul National University Hospital  Seoul Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3895-1915","authenticated-orcid":false,"given":"Seung\u2010Ho","family":"Hur","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Keimyung University Dongsan Medical Center  Daegu Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"In\u2010Whan","family":"Seong","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Chungnam National University Hospital  Daejeon Republic of 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