{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,8]],"date-time":"2025-07-08T20:42:25Z","timestamp":1752007345722,"version":"3.40.5"},"reference-count":14,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2019,7,26]],"date-time":"2019-07-26T00:00:00Z","timestamp":1564099200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2020,2,15]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Percutaneous coronary intervention (PCI) of left main (LM) disease in patients with cardiogenic shock (CS) represents a clinical challenge. Evidence on clinical outcomes according to revascularization strategies in this scenario remains scarce. The objective was to investigate the short\u2010term outcomes according to treatment strategies for this population.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We retrospectively analyzed 78 consecutive patients who underwent PCI of LM in established CS at two experienced centers. Characteristics of PCI and short\u2010term clinical outcomes were assessed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>LM stenosis was considered the culprit lesion in 49 patients (62.8%). In the remaining cases, LM stenosis was treated after successful PCI of the culprit vessel because of persistent CS. The majority of patients presented complex coronary anatomy (43.6% had Syntax score\u2009&gt;\u200932). Complete revascularization was performed in 34.6%; a 2\u2010stents technique in the LM bifurcation was used in 12.8% and intra\u2010aortic balloon pump (IABP) in 73.1%. In\u2010hospital mortality was 48.7%. At 90 days follow\u2010up it was 50% without differences between 1 or 2 stent LM bifurcation\u2010techniques (<jats:italic>p<\/jats:italic> =\u2009.319). Mortality was higher in patients with partial revascularization and residual Syntax score\u2009\u2265\u200915 (<jats:italic>p<\/jats:italic> &lt;\u2009.05 by univariate analysis), and in those with TIMI flow&lt;3 in the left coronary artery at the end of PCI (<jats:italic>p<\/jats:italic> &lt;\u2009.05 by multivariate analysis). There were no significant differences in the use of IABP in relation to 90\u2010day mortality (<jats:italic>p<\/jats:italic> =\u2009.92).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>In patients presenting with cardiogenic shock and LM disease, neither 2\u2010stents strategy in the LM nor use of IABP displayed a reduced short\u2010term mortality. However, patients with final TIMI flow &lt;3 presented higher short\u2010term mortality in our series.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccd.28404","type":"journal-article","created":{"date-parts":[[2019,7,27]],"date-time":"2019-07-27T05:04:08Z","timestamp":1564203848000},"page":"515-521","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Short\u2010term clinical outcomes of percutaneous coronary intervention of unprotected left main coronary disease in cardiogenic shock"],"prefix":"10.1002","volume":"95","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4208-1681","authenticated-orcid":false,"given":"Alex F.","family":"Castro\u2010Mej\u00eda","sequence":"first","affiliation":[{"name":"Department of Cardiology, Cardiovascular Institute Hospital Cl\u00ednico San Carlos  Madrid 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