{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T22:36:29Z","timestamp":1773182189231,"version":"3.50.1"},"reference-count":38,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2019,9,4]],"date-time":"2019-09-04T00:00:00Z","timestamp":1567555200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2020,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To perform clinical and echocardiographic follow\u2010up beyond 1\u2009year in consecutive patients with severe bicuspid aortic stenosis (AS) undergoing transcatheter aortic valve replacement (TAVR) with a current generation balloon\u2010expandable valve.<\/jats:p><\/jats:sec><jats:sec><jats:title>Background<\/jats:title><jats:p>Treatment of bicuspid aortic valve disease with TAVR remains controversial and late follow\u2010up data is still scarce.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We collected baseline characteristics, procedural data, 30\u2010day and mid\u2010term clinical follow\u2010up findings from six centers in Europe and Canada from patients with bicuspid AS treated with TAVR using the SAPIEN 3 valve.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Seventy\u2010nine patients underwent TAVR. Mean age was 76\u2009\u00b1\u20099\u2009years; median STS risk score for mortality was 3.8% (interquartile range 2.3\u20135.5%). Median follow\u2010up was 390\u2009days (interquartile range 138\u2013739\u2009days). Device success was achieved in 95% of patients. Postimplantation mean aortic gradient decreased from 50.2\u2009\u00b1\u200916.2 to 8.8\u2009\u00b1 4.4\u2009mmHg and no patient had more than mild aortic regurgitation. At last follow\u2010up, there was persistent good valve performance. At 30\u2009days and 1 year, the rates of all\u2010cause mortality were 3.8 and 7.7%, stroke 1.2 and 1.2%, and the rate of new pacemakers 18 and 18%.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Our data confirm that treating patients with stenotic bicuspid aortic valves is safe, effective, and has favorable valve performance over time.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccd.28475","type":"journal-article","created":{"date-parts":[[2019,9,4]],"date-time":"2019-09-04T14:19:27Z","timestamp":1567606767000},"page":"1186-1192","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Mid\u2010term outcome in patients with bicuspid aortic valve stenosis following transcatheter aortic valve replacement with a current generation device: A multicenter study"],"prefix":"10.1002","volume":"95","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7814-9444","authenticated-orcid":false,"given":"Adrian","family":"Attinger\u2010Toller","sequence":"first","affiliation":[{"name":"Department of Cardiology St. Paul's Hospital, Vancouver  British Columbia Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rahul","family":"Bhindi","sequence":"additional","affiliation":[{"name":"Department of Cardiology St. Paul's Hospital, Vancouver  British Columbia Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gidon Y.","family":"Perlman","sequence":"additional","affiliation":[{"name":"Department of Cardiology Hadassah Hebrew University Medical Center  Jerusalem Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dale","family":"Murdoch","sequence":"additional","affiliation":[{"name":"Department of Cardiology St. Paul's Hospital, Vancouver  British Columbia Canada"},{"name":"Department of 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