{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T14:10:42Z","timestamp":1753884642728,"version":"3.40.5"},"reference-count":25,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2019,11,12]],"date-time":"2019-11-12T00:00:00Z","timestamp":1573516800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2020,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To evaluate the impact of previous coronary artery bypass grafting (CABG) on early safety at 30\u2009days and 1\u2010year mortality in patients receiving transcatheter aortic valve replacement (TAVR).<\/jats:p><\/jats:sec><jats:sec><jats:title>Background<\/jats:title><jats:p>The use of TAVR in patients with previous CABG suffering from severe aortic stenosis has increased in the last years.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Consecutive TAVR patients were stratified according to previous CABG versus no previous cardiac surgery (control). All\u2010cause 1\u2010year mortality and early safety at 30\u2009days were evaluated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In the unmatched cohort and compared to control (<jats:italic>n<\/jats:italic> = 2,364), CABG (<jats:italic>n<\/jats:italic> = 260) were younger, more often male and suffered more often from comorbidities leading to an increased STS\u2010score (<jats:italic>p<\/jats:italic>\u2009&lt;\u2009.001). The rate of early safety events at 30\u2009days was comparable between CABG and control (21.2% vs. 24.6%, <jats:italic>p<\/jats:italic> = .22) with a higher mortality in CABG (9.6% vs. 5.3%, <jats:italic>p<\/jats:italic> = .005). All\u2010cause 1\u2010year mortality was higher in CABG compared to controls (HR 1.51 [95%\u2010CI 1.15\u20131.97], <jats:italic>p<\/jats:italic> = .003). Applying Cox regression analysis, both 30\u2010day (HR 1.57 [95%\u2010CI 0.97\u20132.53], <jats:italic>p<\/jats:italic> = .067) and all\u2010cause 1\u2010year mortality (HR 1.24 [95%\u2010CI 0.91\u20131.70], <jats:italic>p<\/jats:italic> = .174) were not significantly different between groups.<\/jats:p><jats:p>After propensity\u2010score matching, the rate of early safety events at 30\u2009days was lower in CABG compared to controls (21.6% vs. 31.7%, <jats:italic>p<\/jats:italic> = .02). Thirty\u2010day (9.1% vs. 7.7%, <jats:italic>p<\/jats:italic> = .596) and all\u2010cause 1\u2010year mortality (24.0% vs. 23.1%, <jats:italic>p<\/jats:italic> = .520, HR 1.14 [95%\u2010CI 0.77\u20131.69], <jats:italic>p<\/jats:italic> = .520) were not different between groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>In patients receiving TAVR, previous CABG was not associated with an increase in periprocedural complications and all\u2010cause 1\u2010year mortality when adjusted for other comorbidities.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccd.28515","type":"journal-article","created":{"date-parts":[[2019,11,12]],"date-time":"2019-11-12T16:12:33Z","timestamp":1573575153000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Outcome of patients with previous coronary artery bypass grafting and severe calcific aortic stenosis receiving transfemoral transcatheter aortic valve replacement"],"prefix":"10.1002","volume":"96","author":[{"given":"Robert","family":"H\u00f6llriegel","sequence":"first","affiliation":[{"name":"Department of Internal Medicine and Cardiology Herzzentrum Dresden, Technische Universit\u00e4t Dresden  Dresden Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aileen","family":"Spindler","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine\/Cardiology Heart Center Leipzig at University of Leipzig  Leipzig Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Philipp","family":"Kiefer","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery Heart Center Leipzig at University of Leipzig  Leipzig Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Felix J.","family":"Woitek","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine and Cardiology Herzzentrum Dresden, Technische Universit\u00e4t Dresden  Dresden 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