{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,20]],"date-time":"2026-03-20T16:09:59Z","timestamp":1774022999633,"version":"3.50.1"},"reference-count":27,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2019,11,12]],"date-time":"2019-11-12T00:00:00Z","timestamp":1573516800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2020,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Coronary collaterals are often seen supplying retrograde flow to an acutely occluded arterial territory. Whether this early collateralization offers prognostic benefit is not well established.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We analyzed data from all patients presenting to our regional cardiac unit with acute ST\u2010elevation myocardial infarction requiring immediate angiography (years 1999\u20132017). Data on all patients is entered prospectively into a bespoke tailored database prior to knowledge of patient outcome. Only patients with TIMI 0 or 1 flow in the infarct\u2010related vessel were included in the analysis. In\u2010hospital and long\u2010term outcome were assessed according to the presence or absence of angiographically visible collateral flow prior to treatment of the occluded vessel.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Two thousand five hundred and forty\u2010two patients were included in the analysis. 76% of these (<jats:italic>n<\/jats:italic>=\u20091944) had TIMI 0\/1 flow at angiography. Angiographically\u2010visible collateralization was seen in 17% (<jats:italic>n<\/jats:italic>=\u2009322) and was more commonly observed in the right coronary artery (64%) than in the left anterior descending (25%) or Cx (6%). Cardiogenic shock (10.8%) and use of an intra\u2010aortic balloon pump (5.4%) were more frequent in patients without coronary collateralisation (<jats:italic>p<\/jats:italic>=\u2009.04 and<jats:italic>p<\/jats:italic>=\u2009.02, respectively). The presence of collaterals improved long term survival (95% CI 11.4\u201318.7 months;<jats:italic>p<\/jats:italic>&lt;\u2009.01).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>One\u2010sixth of patients with STEMI have angiographically visible collaterals to the infarcted territory. Patients without collaterals are more likely to present in cardiogenic shock. The presence of angiographically visible collaterals at the time of STEMI is associated with an improved long\u2010term survival.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccd.28532","type":"journal-article","created":{"date-parts":[[2019,11,12]],"date-time":"2019-11-12T13:58:32Z","timestamp":1573567112000},"page":"528-533","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Angiographically visible coronary artery collateral circulation improves prognosis in patients presenting with acute ST segment\u2010elevation myocardial infarction"],"prefix":"10.1002","volume":"96","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0530-4831","authenticated-orcid":false,"given":"Osama","family":"Alsanjari","sequence":"first","affiliation":[{"name":"Sussex Cardiac Centre, Brighton and Sussex University Hospitals Brighton UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tarak","family":"Chouari","sequence":"additional","affiliation":[{"name":"Sussex Cardiac Centre, Brighton and Sussex University Hospitals Brighton UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9315-3529","authenticated-orcid":false,"given":"Timothy","family":"Williams","sequence":"additional","affiliation":[{"name":"Sussex Cardiac Centre, Brighton and Sussex University Hospitals Brighton UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aung","family":"Myat","sequence":"additional","affiliation":[{"name":"Sussex Cardiac Centre, Brighton and Sussex University Hospitals Brighton UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nalyaka","family":"Sambu","sequence":"additional","affiliation":[{"name":"Sussex Cardiac Centre, Brighton and Sussex University Hospitals Brighton UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lucy","family":"Blows","sequence":"additional","affiliation":[{"name":"Sussex Cardiac Centre, Brighton and Sussex University Hospitals Brighton UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7286-4129","authenticated-orcid":false,"given":"James","family":"Cockburn","sequence":"additional","affiliation":[{"name":"Sussex Cardiac Centre, Brighton and Sussex University Hospitals Brighton UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adam","family":"de Belder","sequence":"additional","affiliation":[{"name":"Sussex Cardiac Centre, Brighton and Sussex University Hospitals Brighton UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Hildick\u2010Smith","sequence":"additional","affiliation":[{"name":"Sussex Cardiac Centre, Brighton and Sussex University Hospitals Brighton UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,11,12]]},"reference":[{"key":"e_1_2_6_2_1","volume-title":"The top 10 causes of death","author":"WHO","year":"2017"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0b013e31826e1058"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(03)12113-7"},{"key":"e_1_2_6_5_1","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1016\/S0140-6736(94)91161-4","article-title":"Indications for fibrinolytic therapy in suspected acute myocardial infarction: collaborative overview of early mortality and major morbidity results from all randomised trials of more than 1000 patients. 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