{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T19:01:29Z","timestamp":1760122889495,"version":"3.40.5"},"reference-count":14,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2019,10,24]],"date-time":"2019-10-24T00:00:00Z","timestamp":1571875200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2020,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aims<\/jats:title><jats:p>The commonly used valve\u2010in\u2010valve (VIV) app recommends sizing based on dimensions of both the transcatheter heart valve (THV) and bioprosthetic surgical valve. The implications of hydrodynamic testing to guide VIV sizing are poorly understood. This bench study assessed the hydrodynamic performance of different sizes of self\u2010expanding supra\u2010annular THVs in three different surgical aortic bioprostheses at different implantation depths.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A small versus medium ACURATE neo (ACn), and a 26\u2009mm versus 29\u2009mm Evolut R were assessed after VIV implantation in 25\u2009mm Mitroflow, Mosaic, and Magna Ease aortic surgical bioprostheses, at three implantation depths (+2\u2009mm, \u20102\u2009mm, and \u20106\u2009mm).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The medium\u2010sized ACn had lower gradients compared to the small ACn when the THV was implanted high (+2\u2009mm, or \u20102\u2009mm). The 29\u2009mm Evolut R had lower gradients compared to a 26\u2009mm Evolut R for all implantation depths, except for a depth of \u20102\u2009mm in the 25\u2009mm Mitroflow. The medium ACn and 29\u2009mm Evolut R had larger effective orifice areas compared to the small ACn and 26\u2009mm Evolut R, respectively. Both Evolut R sizes had acceptable regurgitant fractions (&lt;15%), while both ACn sizes were above the acceptable performance criteria (&gt;15%), at all implantation depths.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Use of a larger self\u2010expanding THV was associated with superior hydrodynamic performance if the THV was implanted high. Hydrodynamic testing can provide additional information to the VIV app to help guide VIV sizing.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccd.28537","type":"journal-article","created":{"date-parts":[[2019,10,24]],"date-time":"2019-10-24T17:02:03Z","timestamp":1571936523000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Implications of hydrodynamic testing to guide sizing of self\u2010expanding transcatheter heart valves for valve\u2010in\u2010valve procedures"],"prefix":"10.1002","volume":"96","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9513-9440","authenticated-orcid":false,"given":"Janarthanan","family":"Sathananthan","sequence":"first","affiliation":[{"name":"Centre for Heart Valve Innovation, St Paul's Hospital University of British Columbia  Vancouver Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9270-6446","authenticated-orcid":false,"given":"Mark","family":"Hensey","sequence":"additional","affiliation":[{"name":"Centre for Heart Valve Innovation, St Paul's Hospital University of British Columbia  Vancouver Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rob","family":"Fraser","sequence":"additional","affiliation":[{"name":"ViVitro Labs Inc  Victoria Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Uri","family":"Landes","sequence":"additional","affiliation":[{"name":"Centre for Heart Valve Innovation, St Paul's Hospital University of British Columbia  Vancouver Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Philipp","family":"Blanke","sequence":"additional","affiliation":[{"name":"Centre for Heart Valve Innovation, St Paul's Hospital University of British Columbia  Vancouver Canada"},{"name":"Department of Radiology St. Paul's Hospital and University of British Columbia  Vancouver Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hoda","family":"Hatoum","sequence":"additional","affiliation":[{"name":"Department of Biomedical Engineering The Ohio State University  Columbus Ohio"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lakshmi Prasad","family":"Dasi","sequence":"additional","affiliation":[{"name":"Department of Biomedical Engineering The Ohio State University  Columbus Ohio"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexander","family":"Sedaghat","sequence":"additional","affiliation":[{"name":"Med. Klinik und Poliklinik II, Herzzentrum Universit\u00e4tsklinikum Bonn  Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vinayak N","family":"Bapat","sequence":"additional","affiliation":[{"name":"Columbia University Medical Centre  New York New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jonathon","family":"Leipsic","sequence":"additional","affiliation":[{"name":"Centre for Heart Valve Innovation, St Paul's Hospital University of British Columbia  Vancouver Canada"},{"name":"Department of Radiology St. Paul's Hospital and University of British Columbia  Vancouver Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lars","family":"S\u00f8ndergaard","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Rigshospitalet Copenhagen University Hospital  Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David A.","family":"Wood","sequence":"additional","affiliation":[{"name":"Centre for Heart Valve Innovation, St Paul's Hospital University of British Columbia  Vancouver Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John G.","family":"Webb","sequence":"additional","affiliation":[{"name":"Centre for Heart Valve Innovation, St Paul's Hospital University of British Columbia  Vancouver Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,10,24]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2017.02.057"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.112.104505"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.4244\/EIJV10SUA7"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2016.10.034"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.24419"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0003-4975(00)01167-X"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.4244\/EIJV9I11A215"},{"volume-title":"International Standards Organization","year":"2013","author":"Cardiovascular implants \u2010 cardiac valve prosthesis","key":"e_1_2_8_9_1"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/0021-9290(94)90209-7"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0003-4975(01)03588-3"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.dental.2009.02.001"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2018.10.043"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2016.05.030"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.4244\/EIJ-D-18-00947"}],"container-title":["Catheterization and Cardiovascular Interventions"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fccd.28537","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccd.28537","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ccd.28537","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccd.28537","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,6]],"date-time":"2023-09-06T00:30:23Z","timestamp":1693960223000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccd.28537"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,10,24]]},"references-count":14,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2020,9]]}},"alternative-id":["10.1002\/ccd.28537"],"URL":"https:\/\/doi.org\/10.1002\/ccd.28537","archive":["Portico"],"relation":{},"ISSN":["1522-1946","1522-726X"],"issn-type":[{"type":"print","value":"1522-1946"},{"type":"electronic","value":"1522-726X"}],"subject":[],"published":{"date-parts":[[2019,10,24]]},"assertion":[{"value":"2019-09-15","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-09-27","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-10-24","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}