{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T22:18:09Z","timestamp":1785449889630,"version":"3.56.0"},"reference-count":27,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2019,10,24]],"date-time":"2019-10-24T00:00:00Z","timestamp":1571875200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2020,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>There is a paucity of data regarding the outcomes of transcatheter valve replacement (TAVR) performed in an urgent clinical setting.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The Nationwide Inpatient Sample (NIS) database years 2011\u20132014 was used to identify hospitalizations for TAVR in the urgent setting. Using propensity score matching, we compared patients who underwent TAVR in nonurgent versus urgent settings.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Among 42,154 hospitalizations in which TAVR was performed, 10,114 (24%) underwent urgent TAVR. There was an uptrend in the rate of urgent TAVR procedures (<jats:italic>p<\/jats:italic>\u2009=\u2009.001). The rates of in\u2010hospital mortality among this group did not change during the study period (<jats:italic>p<\/jats:italic>\u2009=\u2009.713). Nonurgent TAVR was associated with lower mortality (odds ratio [OR] = 0.78; 95% confidence interval [CI]: 0.69\u20130.89, <jats:italic>p<\/jats:italic> &lt;\u2009.001) compared with urgent TAVR. Nonurgent TAVR was associated with lower incidence of cardiogenic shock (OR = 0.46; 95%CI: 0.40\u20130.53 <jats:italic>p<\/jats:italic> &lt;\u2009.001), use of mechanical circulatory support devices (OR = 0.69; 95%CI: 0.59\u20130.82, <jats:italic>p<\/jats:italic> &lt;\u2009.001), AKI (OR = 0.60; 95%CI: 0.56\u20130.64 <jats:italic>p<\/jats:italic> &lt;\u2009.001), hemodialysis (OR = 0.67; 95%CI: 0.56\u20130.80 <jats:italic>p<\/jats:italic> &lt;\u2009.001), major bleeding (OR = 0.94; 95%CI: 0.89\u20130.99 <jats:italic>p<\/jats:italic>\u2009=\u2009.045) and shorter length of stay (7.08 \u00b1\u20096.317 vs. 12.39\u2009\u00b1\u20099.737\u2009days, <jats:italic>p<\/jats:italic> &lt;\u2009.001). There was no difference in acute stroke (OR = 0.96; 95%CI: 0.81\u20131.14, <jats:italic>p<\/jats:italic>\u2009=\u2009.636), vascular complications (OR = 1.07; 95%CI: 0.89\u20131.29, <jats:italic>p<\/jats:italic>\u2009=\u2009.492), and pacemaker insertions (OR = 0.92; 95%CI: 0.84\u20131.01, <jats:italic>p<\/jats:italic>\u2009=\u2009.067) between both groups. Among those undergoing urgent TAVR, subgroup analysis showed higher mortality in patients \u226480\u2009years (<jats:italic>p<\/jats:italic>\u2009=\u2009.033), women (<jats:italic>p<\/jats:italic> &lt;\u2009.001), chronic kidney disease (<jats:italic>p<\/jats:italic>\u2009=\u2009.001), heart failure (<jats:italic>p<\/jats:italic> &lt;\u2009.001), and liver disease (<jats:italic>p<\/jats:italic>\u2009=\u2009.003).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>In this large nationwide analysis, almost a quarter of TAVR procedures were performed in the urgent settings. Although urgent TAVR was associated with higher mortality and increased complications compared with nonurgent TAVR, the absolute difference in in\u2010hospital mortality was not remarkably higher. Thus, urgent TAVR can be considered as a reasonable approach when indicated.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccd.28563","type":"journal-article","created":{"date-parts":[[2019,10,24]],"date-time":"2019-10-24T17:03:07Z","timestamp":1571936587000},"page":"189-195","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":27,"title":["Outcomes of urgent versus nonurgent transcatheter aortic valve replacement"],"prefix":"10.1002","volume":"96","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4248-781X","authenticated-orcid":false,"given":"Ayman","family":"Elbadawi","sequence":"first","affiliation":[{"name":"Department of Cardiovascular Medicine University of Texas Medical Branch  Galveston Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9853-7591","authenticated-orcid":false,"given":"Islam Y.","family":"Elgendy","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Massachusetts General Hospital and Harvard Medical School  Boston MA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amgad","family":"Mentias","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Medicine University of Iowa  Iowa City Iowa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2280-8030","authenticated-orcid":false,"given":"Marwan","family":"Saad","sequence":"additional","affiliation":[{"name":"Cardiovascular Institute, The Warren Alpert Medical School of Brown University, Providence  RI USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmed H.","family":"Mohamed","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Rochester General Hospital  Rochester New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muhammad Waqas","family":"Choudhry","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine University of Texas Medical Branch  Galveston Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4140-8067","authenticated-orcid":false,"given":"Gbolahan O.","family":"Ogunbayo","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine University of Kentucky  Lexington Kentucky"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Syed","family":"Gilani","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine University of Texas Medical Branch  Galveston Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hani","family":"Jneid","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Medicine Baylor School of Medicine  Houston Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,10,24]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0195-668X(03)00201-X"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2007.12.042"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.2010.206367"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.4244\/EIJ-D-18-00029"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2018.03.002"},{"key":"e_1_2_7_7_1","volume-title":"Clinical classifications for health policy research: version 2: software and User's guide: US Department of Health and Human Services","author":"Elixhauser A","year":"1996"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2018.12.002"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.28050"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2009.08.006"},{"key":"e_1_2_7_11_1","article-title":"MatchIt: nonparametric preprocessing for parametric causal inference","volume":"42","author":"Ho DE","year":"2006","journal-title":"J Stat Softw"},{"key":"e_1_2_7_12_1","unstructured":"HouchensR RossD ElixhauserA.Using the HCUP national inpatient sample to estimate trends. 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