{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T09:32:15Z","timestamp":1762507935238,"version":"3.40.5"},"reference-count":14,"publisher":"Wiley","issue":"S1","license":[{"start":{"date-parts":[[2019,12,23]],"date-time":"2019-12-23T00:00:00Z","timestamp":1577059200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2020,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>This study aimed to evaluate the effect of stenting on blood pressure in hypertensive patients with symptomatic proximal subclavian or vertebral artery stenosis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Background<\/jats:title><jats:p>Whether posterior circulation revascularization could reduce blood pressure in hypertensive patients with posterior circulation hypoperfusion has not been investigated in humans.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A total of 48 patients with essential hypertension (33 males; mean age 63.0\u2009\u00b1\u20098.7 years) with symptomatic proximal subclavian or vertebral artery stenosis who underwent stenting successfully at the Fuwai Hospital were prospectively enrolled between January 2014 and December 2015. All 48 patients were followed up at 1, 3, and 6 months after the procedure. Blood pressure, use of antihypertensive agents, and complications were investigated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Baseline values included office blood pressure of 132\/77\u2009\u00b1\u200910\/8 mmHg, mean 24\u2010hr blood pressure of 127\/75\u2009\u00b1\u200912\/9 mmHg, and mean antihypertensive agents used of 1.6\u2009\u00b1\u20090.8. Stenosis of the subclavian and vertebral arteries decreased from 88.9\u2009\u00b1\u20099.5% and 85.8\u2009\u00b1\u20097.4% to 5.5\u2009\u00b1\u20093.5% and 4.6\u2009\u00b1\u20093.7%, respectively, immediately after the procedure. Reductions in office blood pressure were\u2009\u2212\u20097\/\u22123 (<jats:italic>SD<\/jats:italic> 3\/2), \u22129\/\u22124 (5\/3), and\u2009\u2212\u200910\/\u22125 (7\/5) mmHg at 1, 3, and 6 months, respectively. While 24\u2010hr blood pressures after the procedure reduced by \u22125\/\u22123 mmHg at 6 months, the total number of antihypertensive agents used at the aforementioned time points was unchanged.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This first prospective cohort study in humans showed that posterior circulation stenting is apparently effective in reducing blood pressure in hypertensive patients with symptomatic proximal subclavian or vertebral artery stenosis.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccd.28650","type":"journal-article","created":{"date-parts":[[2019,12,23]],"date-time":"2019-12-23T10:23:30Z","timestamp":1577096610000},"page":"633-640","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["The effect of stenting on blood pressure in hypertensive patients with symptomatic proximal subclavian or vertebral artery stenosis"],"prefix":"10.1002","volume":"95","author":[{"given":"Wuqiang","family":"Che","sequence":"first","affiliation":[{"name":"Department of Cardiology China\u2010Japan Friendship Hospital  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hui","family":"Dong","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Fuwai Hospital, National Center for Cardiovascular Disease Chinese Academy of Medical Sciences and Peking Union Medical College  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3628-6595","authenticated-orcid":false,"given":"Xiongjing","family":"Jiang","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Fuwai Hospital, National Center for Cardiovascular Disease Chinese Academy of Medical Sciences and Peking Union Medical College  Beijing 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