{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,13]],"date-time":"2025-05-13T14:40:36Z","timestamp":1747147236345,"version":"3.40.5"},"reference-count":34,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2019,12,23]],"date-time":"2019-12-23T00:00:00Z","timestamp":1577059200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2020,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Patients treated with primary percutaneous coronary intervention (pPCI) for ST elevation myocardial infarction (STEMI) who have a history of coronary artery bypass grafting (CABG) are at high risk of adverse cardiovascular outcomes. Data on the risk of a saphenous vein graft (SVG)\u2014infarct\u2010related artery (IRA) compared to other culprit vessels are sparse.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The study was based on a prospectively collected registry of 2,405 consecutive patients with STEMI attending a tertiary medical center in 2001\u20132017. Patients with an SVG\u2010IRA (<jats:italic>n<\/jats:italic> =\u2009172) were compared with patients with native vessel disease (<jats:italic>n<\/jats:italic> =\u20092,333) for mortality and major adverse cardiac events (MACE), which included death, myocardial infarction (MI), target vessel revascularization (TVR), and coronary artery bypass surgery (CABG) at 1 month and 3\u2009years.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The SVG\u2010IRA group was significantly older than the native vessel group (<jats:italic>p<\/jats:italic> =\u2009.05), with no between\u2010group differences in rates of male patients (76 vs. 82%, <jats:italic>p<\/jats:italic> =\u2009.59), diabetes (24.2 vs. 26.2%, <jats:italic>p<\/jats:italic> =\u2009.73), and renal failure (18.8 vs. 9.2%, <jats:italic>p<\/jats:italic> =\u2009.25). Mortality was higher in the SVG\u2010IRA group at 1 month (13.9 vs. 2.5%, <jats:italic>p<\/jats:italic> &lt;\u2009.01) and 3\u2009years (23.9 vs. 7.4%, <jats:italic>p<\/jats:italic> &lt;\u2009.01). At 3\u2009years, SVG\u2010IRA was associated with the highest rates of MACE (55.6%), compared with native vessel disease. After correction for confounders, SVG\u2010IRA remained an independent risk factor for MACE both at 1 month (HR\u20102.08, 95%CI 1.72\u20133.11, <jats:italic>p<\/jats:italic> &lt;\u2009.01) and 3\u2009years (HR\u20102.01, 95%CI 1.28\u20133.09, <jats:italic>p<\/jats:italic> &lt;\u2009.01).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Among patients treated with pPCI for STEMI, outcomes are worse when the culprit is an SVG.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccd.28662","type":"journal-article","created":{"date-parts":[[2019,12,23]],"date-time":"2019-12-23T10:06:27Z","timestamp":1577095587000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Outcomes of primary percutaneous cardiac intervention for ST elevation myocardial infarction with a saphenous vein graft culprit"],"prefix":"10.1002","volume":"96","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7735-4419","authenticated-orcid":false,"given":"Mark","family":"Kheifets","sequence":"first","affiliation":[{"name":"Department of Cardiology, Rabin Medical Center, Petach Tikva and the Sackler Faculty of Medicine Tel Aviv University  Tel Aviv Israel"},{"name":"Department of Internal Medicine B Meir Medical Center  Kfar\u2010Saba Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hana","family":"Vaknin\u2010Assa","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Rabin Medical Center, Petach Tikva and the Sackler Faculty of Medicine Tel Aviv University  Tel Aviv Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gabriel","family":"Greenberg","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Rabin Medical Center, Petach Tikva and the Sackler Faculty of Medicine Tel Aviv University  Tel Aviv 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