{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,20]],"date-time":"2026-04-20T13:50:31Z","timestamp":1776693031241,"version":"3.51.2"},"reference-count":14,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2019,12,26]],"date-time":"2019-12-26T00:00:00Z","timestamp":1577318400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2020,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To assess the outcomes and potential predictors of residual leak after implantation of the GORE CARDIOFORM Septal Occluder (GSO) in secundum atrial septal defects (ASDs).<\/jats:p><\/jats:sec><jats:sec><jats:title>Background<\/jats:title><jats:p>The non\u2010self\u2010centering design of the GSO could lead to residual leak at the edge of the device. Outcomes of residual leak are poorly understood.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Retrospective, multicenter review of patients treated with the GSO for the pivotal and continued access study. Procedural, echocardiographic, and follow up data were reviewed. Multivariate analysis was performed to determine predictors of leak at implant and outcomes of these leaks.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There were 370 total ASD device closures with the GSO, 65 (17.56%) of which were found to have residual leak at implantation. Patients with residual leak had larger defects (10.33\u2009\u00b1\u20093.05\u2009mm vs. 9.13\u2009\u00b1\u20092.89\u2009mm, <jats:italic>p<\/jats:italic> =\u2009.006) and smaller aortic rims (4.87\u2009\u00b1\u20093.33\u2009mm vs. 6.17\u2009\u00b1\u20093.78\u2009mm, <jats:italic>p<\/jats:italic> =\u2009.019), as compared to those without leak. Larger devices were implanted (<jats:italic>p<\/jats:italic> =\u2009.008) and more devices per case (<jats:italic>p<\/jats:italic> =\u2009.007) were utilized in the residual leak cohort as compared to those without leak. Overall, among patients with residual leak, there was a significant decrease in leak size over 1 year, from 1.55\u2009\u00b1\u20090.75\u2009mm to 0.25\u2009\u00b1\u20090.74\u2009mm (<jats:italic>p<\/jats:italic> &lt;\u2009.001), with the majority (87.6%) disappearing by 12\u2010month follow\u2010up.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Residual leak at implantation can be seen after ASD device closure with the GSO, more commonly in larger defects with smaller retroaortic rims. The vast majority of these leaks completely resolve by 1 year follow up.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccd.28666","type":"journal-article","created":{"date-parts":[[2019,12,26]],"date-time":"2019-12-26T11:29:52Z","timestamp":1577359792000},"page":"932-936","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Here today, gone tomorrow: Outcomes of residual leak following secundum atrial septal defect closure with the GORE CARDIOFORM Septal Occluder"],"prefix":"10.1002","volume":"95","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7671-3766","authenticated-orcid":false,"given":"Brent M.","family":"Gordon","sequence":"first","affiliation":[{"name":"Division of Pediatric Cardiology Loma Linda University Medical Center  Loma Linda California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6366-4205","authenticated-orcid":false,"given":"Islam","family":"Abudayyeh","sequence":"additional","affiliation":[{"name":"Division of Cardiology Loma Linda University Medical Center  Loma Linda California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jake","family":"Goble","sequence":"additional","affiliation":[{"name":"WL Gore Industries  Flagstaff Arizona"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nancy A.","family":"Collado","sequence":"additional","affiliation":[{"name":"School of Public Health Loma Linda University  Loma Linda California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0726-1337","authenticated-orcid":false,"given":"Joseph","family":"Paolillo","sequence":"additional","affiliation":[{"name":"Division of Pediatric Cardiology Sanger Heart &amp; Vascular Institute\/Levine Children's Hospital  Charlotte North Carolina"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,12,26]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00246-016-1350-6"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.25494"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.24851"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.25216"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.26881"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.2459\/JCM.0000000000000036"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.4244\/EIJV9I8A160"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/joic.12528"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.26585"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2018.01.262"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCINTERVENTIONS.116.004212"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.26907"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00246-009-9623-y"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2012.04.081"}],"container-title":["Catheterization and Cardiovascular Interventions"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fccd.28666","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccd.28666","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ccd.28666","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccd.28666","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,7]],"date-time":"2023-09-07T15:52:09Z","timestamp":1694101929000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccd.28666"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,12,26]]},"references-count":14,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2020,4]]}},"alternative-id":["10.1002\/ccd.28666"],"URL":"https:\/\/doi.org\/10.1002\/ccd.28666","archive":["Portico"],"relation":{},"ISSN":["1522-1946","1522-726X"],"issn-type":[{"value":"1522-1946","type":"print"},{"value":"1522-726X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,12,26]]},"assertion":[{"value":"2019-10-08","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-12-08","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-12-26","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}