{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T00:45:40Z","timestamp":1780447540044,"version":"3.54.1"},"reference-count":32,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2020,3,17]],"date-time":"2020-03-17T00:00:00Z","timestamp":1584403200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2021,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To compare the postprocedural optical coherence tomography (OCT) findings and in\u2010hospital outcomes among the three subtypes of calcified plaques: eruptive calcified nodules, superficial calcific sheet, and calcified protrusion.<\/jats:p><\/jats:sec><jats:sec><jats:title>Background<\/jats:title><jats:p>Recently, three subtypes of calcified culprit plaques were reported in patients with acute coronary syndrome (ACS). How these subtypes respond to stenting is unknown.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>ACS patients with calcified plaque at the culprit lesion were selected from our database. OCT findings at baseline and after stent implantation were compared.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In the final analysis, 87 cases were included. Preprocedural OCT showed eruptive calcified nodules in 19 (21.8%) cases, superficial calcific sheet in 63 (72.4%), and calcified protrusion in 5 (5.7%). Stent edge dissection (SED) and incomplete stent apposition (ISA) were frequently observed in the eruptive calcified nodules group compared to superficial calcific sheet or calcified protrusion (SED; 47.4% vs. 17.5% vs. 20.0%; <jats:italic>p<\/jats:italic> = .032, ISA; 94.7% vs. 58.7% vs. 0.0%; <jats:italic>p<\/jats:italic>\u2009&lt;\u2009.001). The superficial calcific sheet group had the smallest minimal stent area (MSA) among the three groups (eruptive calcified nodules vs. superficial calcific sheet vs. calcified protrusion: 6.29\u2009\u00b1\u20092.41 vs. 4.72\u2009\u00b1\u20091.37 vs. 6.56\u2009\u00b1\u20091.13; <jats:italic>p<\/jats:italic> = .007). The superficial calcific sheet group had a higher rate of periprocedural myocardial infarction compared to the eruptive calcified nodules group (60.3% vs. 31.6%; <jats:italic>p<\/jats:italic> = .028).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>This study demonstrated eruptive calcified nodules are associated with higher incidence of SED and ISA, whereas superficial calcific sheets are associated with small MSA and higher periprocedural myocardial infarction.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccd.28847","type":"journal-article","created":{"date-parts":[[2020,3,17]],"date-time":"2020-03-17T11:30:24Z","timestamp":1584444624000},"page":"634-645","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Comparison of post\u2010stent optical coherence tomography findings among three subtypes of calcified culprit plaques in patients with acute coronary syndrome"],"prefix":"10.1002","volume":"97","author":[{"given":"Akihiro","family":"Nakajima","sequence":"first","affiliation":[{"name":"Cardiology Division Massachusetts General Hospital, Harvard Medical School  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Makoto","family":"Araki","sequence":"additional","affiliation":[{"name":"Cardiology Division Massachusetts General Hospital, Harvard Medical School  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Osamu","family":"Kurihara","sequence":"additional","affiliation":[{"name":"Cardiology Division Massachusetts General Hospital, Harvard Medical School  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2745-9682","authenticated-orcid":false,"given":"Yoshiyasu","family":"Minami","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine Kitasato University 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Inzai Chiba Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takumi","family":"Higuma","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department of Internal Medicine St. Marianna University School of Medicine  Kanagawa Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4004-5292","authenticated-orcid":false,"given":"Tsunekazu","family":"Kakuta","sequence":"additional","affiliation":[{"name":"Department of Cardiology Tsuchiura Kyodo General Hospital  Tsuchiura Ibaraki Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tom","family":"Adriaenssens","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine University Hospitals Leuven  Leuven Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hang","family":"Lee","sequence":"additional","affiliation":[{"name":"Biostatistics Center Massachusetts General Hospital, Harvard 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