{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,13]],"date-time":"2025-05-13T14:41:11Z","timestamp":1747147271486,"version":"3.40.5"},"reference-count":24,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2020,5,6]],"date-time":"2020-05-06T00:00:00Z","timestamp":1588723200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2021,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>We aimed to assess the in\u2010hospital outcomes in patients with mitral regurgitation treated with percutaneous mitral valve repair (PMVR) among patients with chronic obstructive pulmonary disease (COPD).<\/jats:p><\/jats:sec><jats:sec><jats:title>Background<\/jats:title><jats:p>There is lack of data on the outcomes of PMVR for mitral regurgitation in patients with COPD.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We analyzed the national inpatient sample (NIS) database from January 2012 to December 2016.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 9125 patients underwent PMVR in the period between January 2012 and December 2016, of whom 2,495 (27.3%) patients had concomitant COPD. Comparing COPD patients to non\u2010COPD patients, COPD patients had higher proportion of females (48.3% vs. 46.6%, <jats:italic>p<\/jats:italic> = .16), were younger (75.8\u2009\u00b1\u200910.0\u2009years vs. 76.4\u2009\u00b1\u200912.2\u2009years; <jats:italic>p<\/jats:italic> = .04), had higher prevalence of peripheral vascular disease (17.4% vs. 13.5%; <jats:italic>p<\/jats:italic>\u2009&lt;\u2009.01) and renal failure (39.3% vs. 37%; <jats:italic>p<\/jats:italic>\u2009&lt;\u2009.01). After propensity matching, there was no significant difference in mortality among the COPD group versus non\u2010COPD patients (2.6% vs. 2.9%; <jats:italic>p<\/jats:italic> = .6). Patients with COPD had higher proportion of in\u2010hospital morbidities including St\u2010segment elevation myocardial infarction (1.8% vs. 1.0%; <jats:italic>p<\/jats:italic> = .02), cardiogenic shock (1.4% vs. 0.4%; <jats:italic>p<\/jats:italic>\u2009&lt;\u2009.01), vascular complications (2% vs. 0.8; <jats:italic>p<\/jats:italic>\u2009&lt;\u2009.01), pneumothorax (1% vs. 0.4%; <jats:italic>p<\/jats:italic>\u2009&lt;\u2009.01), and septic shock (1.2% vs. 0.4%; <jats:italic>p<\/jats:italic>\u2009&lt;\u2009.01). Moreover, surrogates of severe disability (mechanical intubation and non\u2010home discharges), cost of hospitalization, and length of stay were higher in the COPD group.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>There was no difference in mortality between the COPD and non\u2010COPD patients after PMVR. Moreover, we observed higher rates of in\u2010hospital morbidities, surrogates of severe disability, and higher resources utilization by the COPD group.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccd.28913","type":"journal-article","created":{"date-parts":[[2020,5,6]],"date-time":"2020-05-06T20:51:01Z","timestamp":1588798261000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["In\u2010hospital outcomes of percutaneous mitral valve repair in patients with chronic obstructive pulmonary disease: insights from the national inpatient sample database"],"prefix":"10.1002","volume":"97","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5097-5568","authenticated-orcid":false,"given":"Mohammed","family":"Osman","sequence":"first","affiliation":[{"name":"Division of Cardiovascular Medicine Heart &amp; Vascular Institute, West Virginia University  Morgantown West Virginia USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Muhammad Zia","family":"Khan","sequence":"additional","affiliation":[{"name":"Department of Medicine West Virginia University  Morgantown West Virginia USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter D.","family":"Farjo","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Medicine Heart &amp; Vascular Institute, West Virginia University  Morgantown West Virginia USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Muhammad U.","family":"Khan","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Medicine Heart &amp; Vascular Institute, West Virginia University  Morgantown West Virginia USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1559-6911","authenticated-orcid":false,"given":"Safi U.","family":"Khan","sequence":"additional","affiliation":[{"name":"Department of Medicine West Virginia University  Morgantown West Virginia USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9076-2321","authenticated-orcid":false,"given":"Mina M.","family":"Benjamin","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Medicine Heart &amp; Vascular Institute, West Virginia University  Morgantown West Virginia USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Muhammad Bilal","family":"Munir","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Medicine Heart &amp; Vascular Institute, West Virginia University  Morgantown West Virginia USA"},{"name":"Division of Cardiovascular Medicine University of California San Diego  La Jolla California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sudarshan","family":"Balla","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Medicine Heart &amp; Vascular Institute, West Virginia University  Morgantown West Virginia USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,5,6]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(06)69208-8"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1136\/heartjnl-2017-312605"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1806640"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehm001"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2009.05.056"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2017.07.025"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.jvca.2017.12.016"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201604-0690SO"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12872-017-0622-2"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2015.1474"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.24586"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/jocs.14325"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00392-015-0872-x"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/ejhf.864"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2015.10.102"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1093\/ejcts\/ezr271"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2009.05.034"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1009355"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1805374"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.27366"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0201376"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurjhf\/hfn013"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.1983.00350030039007"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1080\/15412555.2016.1238450"}],"container-title":["Catheterization and Cardiovascular Interventions"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fccd.28913","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccd.28913","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ccd.28913","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccd.28913","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,3]],"date-time":"2023-09-03T16:12:12Z","timestamp":1693757532000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccd.28913"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,5,6]]},"references-count":24,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2021,1]]}},"alternative-id":["10.1002\/ccd.28913"],"URL":"https:\/\/doi.org\/10.1002\/ccd.28913","archive":["Portico"],"relation":{},"ISSN":["1522-1946","1522-726X"],"issn-type":[{"type":"print","value":"1522-1946"},{"type":"electronic","value":"1522-726X"}],"subject":[],"published":{"date-parts":[[2020,5,6]]},"assertion":[{"value":"2019-12-02","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-04-06","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-05-06","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}