{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T06:13:16Z","timestamp":1777356796755,"version":"3.51.4"},"reference-count":7,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2020,5,5]],"date-time":"2020-05-05T00:00:00Z","timestamp":1588636800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2021,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To determine whether COVID\u201019 may adversely affect outcome of myocardial infarction (MI) patients in Hong Kong, China.<\/jats:p><\/jats:sec><jats:sec><jats:title>Background<\/jats:title><jats:p>The COVID\u201019 pandemic has infected thousands of people and placed enormous stress on healthcare system. Apart from being an infectious disease, it may affect human behavior and healthcare resource allocation which potentially cause treatment delay in MI.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This was a single center cross\u2010sectional observational study. From November 1, 2019 to March 31, 2020, we compared outcome of patients admitted for acute ST\u2010elevation MI (STEMI) and non\u2010ST elevation MI (NSTEMI) before (group 1) and after (group 2) January 25, 2020 which was the date when Hong Kong hospitals launched emergency response measures to combat COVID\u201019.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There was a reduction in daily emergency room attendance since January 25, 2020 (group 1,327\/day vs. group 2,231\/day) and 149 patients with diagnosis of MI were included into analysis (group 1 <jats:italic>N<\/jats:italic> = 85 vs. group 2\u2009<jats:italic>N<\/jats:italic> = 64). For STEMI, patients in group 2 tended to have longer symptom\u2010to\u2010first medical contact time and more presented out of revascularization window (group 1 27.8 vs. group 2 33%). The primary composite outcome of in\u2010hospital death, cardiogenic shock, sustained ventricular tachycardia or fibrillation (VT\/VF) and use of mechanical circulatory support (MCS) was significantly worse in group 2 (14.1 vs. 29.7%, <jats:italic>p<\/jats:italic> = .02).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>More MI patients during COVID\u201019 outbreak had complicated in\u2010hospital course and worse outcomes. Besides direct infectious complications, cardiology community has to acknowledge the indirect effect of communicable disease on our patients and system of care.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccd.28943","type":"journal-article","created":{"date-parts":[[2020,5,5]],"date-time":"2020-05-05T08:58:49Z","timestamp":1588669129000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":45,"title":["Impact of coronavirus disease 2019 (<scp>COVID<\/scp>\u201019) outbreak on outcome of myocardial infarction in Hong Kong, China"],"prefix":"10.1002","volume":"97","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4159-7635","authenticated-orcid":false,"given":"Chor\u2010Cheung Frankie","family":"Tam","sequence":"first","affiliation":[{"name":"Cardiology Division, Department of Medicine, Queen Mary Hospital The University of Hong Kong  Hong Kong China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0995-4623","authenticated-orcid":false,"given":"Kent\u2010Shek","family":"Cheung","sequence":"additional","affiliation":[{"name":"Department of Accident and Emergency Department, Queen Mary Hospital the University of Hong Kong  Hong Kong China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Simon","family":"Lam","sequence":"additional","affiliation":[{"name":"Cardiology Division, Department of Medicine, Queen Mary Hospital The University of Hong Kong  Hong Kong China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anthony","family":"Wong","sequence":"additional","affiliation":[{"name":"Cardiology Division, Department of Medicine, Queen Mary Hospital The University of Hong Kong  Hong Kong China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arthur","family":"Yung","sequence":"additional","affiliation":[{"name":"Cardiology Division, Department of Medicine, Queen Mary Hospital The University of Hong Kong  Hong Kong China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Sze","sequence":"additional","affiliation":[{"name":"Cardiology Division, Department of Medicine, Queen Mary Hospital The University of Hong Kong  Hong Kong China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jonathan","family":"Fang","sequence":"additional","affiliation":[{"name":"Cardiology Division, Department of Medicine, Queen Mary Hospital The University of Hong Kong  Hong Kong China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hung\u2010Fat","family":"Tse","sequence":"additional","affiliation":[{"name":"Cardiology Division, Department of Medicine, Queen Mary Hospital The University of Hong Kong  Hong Kong China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chung\u2010Wah","family":"Siu","sequence":"additional","affiliation":[{"name":"Cardiology Division, Department of Medicine, Queen Mary Hospital The University of Hong Kong  Hong Kong China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,5,5]]},"reference":[{"issue":"1","key":"e_1_2_8_2_1","first-page":"157","article-title":"WHO declares COVID\u201019 a pandemic","volume":"91","author":"Cucinotta D","year":"2020","journal-title":"Acta Biomed"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2002032"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCOUTCOMES.120.006631"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0000000000000617"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0000000000000134"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehx393"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehv320"}],"container-title":["Catheterization and 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