{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,26]],"date-time":"2025-09-26T04:59:10Z","timestamp":1758862750138,"version":"3.40.5"},"reference-count":27,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2020,4,27]],"date-time":"2020-04-27T00:00:00Z","timestamp":1587945600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2021,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To evaluate outcome assessment of percutaneous balloon aortic valvuloplasty (BAV) in different flow and gradient patterns of severe aortic stenosis (AS).<\/jats:p><\/jats:sec><jats:sec><jats:title>Background<\/jats:title><jats:p>The mean pressure gradient reduction after BAV is an often\u2010used surrogate parameter to evaluate procedural success. The definition of a successful BAV has not been evaluated in different subgroups of severe AS, which were introduced in the latest guidelines on the management of patients with valvular heart disease.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>In this observational study, consecutive patients from July 2009 to March 2018 undergoing BAV were divided into normal\u2010flow high\u2010gradient (NFHG), low\u2010flow low\u2010gradient (LFLG), and paradoxical low\u2010flow low\u2010gradient (pLFLG) AS. Baseline characteristics, hemodynamic, and clinical information were collected and compared.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>One\u2010hundred\u2010fifty\u2010six patients were grouped into NFHG (n = 68, 43.5%), LFLG (n = 68, 43.5%), and pLFLG (n = 20, 12.8%) AS. Mean age of the study population was 81\u2009years. Cardiogenic shock or refractory heart failure (46.8%) was the most common underlying reasons for BAV. Spearman correlation revealed that the mean pressure gradient reduction, determined by echocardiography, had a moderate correlation with the increase in the aortic valve area (AVA) in patients with NFHG AS (\u03c1: 0.529, <jats:italic>p<\/jats:italic> &lt;\u2009.001) but showed no association in patients with LFLG (\u03c1: 0.017, <jats:italic>p<\/jats:italic> =\u2009.289) and pLFLG (\u03c1: 0.030, <jats:italic>p<\/jats:italic> =\u2009.889) AS. BAV as bridge to surgical or transcatheter aortic valve replacement was possible in 44.2% of patients, with no difference between groups (<jats:italic>p<\/jats:italic> =\u2009.070).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The mean pressure gradient reduction might be an adequate surrogate parameter for BAV success in patients with NFHG AS but is not suitable for patients with other hemodynamic entities.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccd.28950","type":"journal-article","created":{"date-parts":[[2020,4,27]],"date-time":"2020-04-27T19:38:17Z","timestamp":1588016297000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Contemporary use of balloon aortic valvuloplasty and evaluation of its success in different hemodynamic entities of severe aortic valve stenosis"],"prefix":"10.1002","volume":"97","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9746-7592","authenticated-orcid":false,"given":"Kerstin","family":"Piayda","sequence":"first","affiliation":[{"name":"Medical Faculty, Division of Cardiology, Heinrich\u2010Heine\u2010University D\u00fcsseldorf Pulmonology and Vascular Medicine  D\u00fcsseldorf Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna Christina","family":"Wimmer","sequence":"additional","affiliation":[{"name":"Medical Faculty, Division of Cardiology, Heinrich\u2010Heine\u2010University D\u00fcsseldorf Pulmonology and Vascular Medicine  D\u00fcsseldorf Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Horst","family":"Sievert","sequence":"additional","affiliation":[{"name":"CardioVascularCenter (CVC) Frankfurt  Frankfurt Germany"},{"name":"Germany and Anglia Ruskin University  Chelmsford UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1287-4605","authenticated-orcid":false,"given":"Katharina","family":"Hellhammer","sequence":"additional","affiliation":[{"name":"Medical Faculty, Division of Cardiology, Heinrich\u2010Heine\u2010University D\u00fcsseldorf Pulmonology and Vascular Medicine  D\u00fcsseldorf Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shazia","family":"Afzal","sequence":"additional","affiliation":[{"name":"Medical Faculty, Division of Cardiology, Heinrich\u2010Heine\u2010University D\u00fcsseldorf Pulmonology and Vascular Medicine  D\u00fcsseldorf Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2744-2154","authenticated-orcid":false,"given":"Verena","family":"Veulemans","sequence":"additional","affiliation":[{"name":"Medical Faculty, Division of Cardiology, Heinrich\u2010Heine\u2010University D\u00fcsseldorf Pulmonology and Vascular Medicine  D\u00fcsseldorf Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christian","family":"Jung","sequence":"additional","affiliation":[{"name":"Medical Faculty, Division of Cardiology, Heinrich\u2010Heine\u2010University D\u00fcsseldorf Pulmonology and Vascular Medicine  D\u00fcsseldorf Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Malte","family":"Kelm","sequence":"additional","affiliation":[{"name":"Medical Faculty, Division of Cardiology, Heinrich\u2010Heine\u2010University D\u00fcsseldorf Pulmonology and Vascular Medicine  D\u00fcsseldorf Germany"},{"name":"Cardiovascular Research Institute D\u00fcsseldorf (CARID)  D\u00fcsseldorf Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tobias","family":"Zeus","sequence":"additional","affiliation":[{"name":"Medical Faculty, Division of Cardiology, Heinrich\u2010Heine\u2010University D\u00fcsseldorf Pulmonology and Vascular Medicine  D\u00fcsseldorf Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,4,27]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0195-668X(03)00201-X"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/ejcts\/ezx389"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehx391"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198807213190301"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/0735-1097(91)90726-P"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.1810290102"},{"issue":"8","key":"e_1_2_8_8_1","first-page":"341","article-title":"Balloon aortic valvuloplasty in the transcatheter aortic valve replacement era","volume":"28","author":"Kumar A","year":"2016","journal-title":"J Invasive Cardiol"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2017.07.024"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCINTERVENTIONS.116.004481"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(10)80120-2"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.4244\/EIJ-D-18-00029"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1093\/ehjci\/jew335"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2012.09.002"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00392-008-0650-0"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2017.08.001"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCINTERVENTIONS.111.967836"},{"issue":"8","key":"e_1_2_8_18_1","first-page":"985","article-title":"Aortic valve area discrepancy by Gorlin equation and Doppler echocardiography continuity equation: relationship to flow in patients with valvular aortic stenosis","volume":"16","author":"Burwash IG","year":"2000","journal-title":"Can J Cardiol"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.28146"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.26434"},{"issue":"10","key":"e_1_2_8_21_1","first-page":"380","article-title":"Outcome of patients undergoing transcatheter aortic valve implantation after prior balloon aortic Valvuloplasty","volume":"30","author":"Giordano A","year":"2018","journal-title":"J Invasive Cardiol"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1136\/openhrt-2016-000421"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.106.657098"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2010.08.014"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.27820"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1136\/heartjnl-2016-311037"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2015.07.030"},{"issue":"1","key":"e_1_2_8_28_1","first-page":"30","article-title":"Systematic review and meta\u2010analysis of interventional emergency treatment of decompensated severe aortic stenosis","volume":"32","author":"Wernly B","year":"2019","journal-title":"J Invasive Cardiol"}],"container-title":["Catheterization and Cardiovascular Interventions"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fccd.28950","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccd.28950","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ccd.28950","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccd.28950","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,3]],"date-time":"2023-09-03T16:11:43Z","timestamp":1693757503000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccd.28950"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,4,27]]},"references-count":27,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2021,1]]}},"alternative-id":["10.1002\/ccd.28950"],"URL":"https:\/\/doi.org\/10.1002\/ccd.28950","archive":["Portico"],"relation":{},"ISSN":["1522-1946","1522-726X"],"issn-type":[{"type":"print","value":"1522-1946"},{"type":"electronic","value":"1522-726X"}],"subject":[],"published":{"date-parts":[[2020,4,27]]},"assertion":[{"value":"2020-02-24","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-04-18","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-04-27","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}