{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,13]],"date-time":"2025-05-13T14:41:17Z","timestamp":1747147277351,"version":"3.40.5"},"reference-count":17,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2020,5,8]],"date-time":"2020-05-08T00:00:00Z","timestamp":1588896000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2020,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>This study aimed to examine the feasibility and safety of noncontrast percutaneous coronary intervention (PCI) in patients with acute coronary syndrome (ACS).<\/jats:p><\/jats:sec><jats:sec><jats:title>Background<\/jats:title><jats:p>Contrast\u2010induced acute kidney injury (CI\u2010AKI) occurs in 10\u201320% of ACS patients undergoing PCI, resulting in poor short\u2010 and long\u2010term prognoses. Reducing the amount of contrast medium can prevent CI\u2010AKI.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This was a prospective single\u2010center study. In successful noncontrast PCI, contrast medium was not injected from guiding catheter engagement to wire removal in ad\u2010hoc PCI. Coronary angiography after PCI was permitted once. CI\u2010AKI was defined as an increase in the serum creatinine level of \u22650.5 mg\/dl or \u22651.25 times the baseline within 72\u2009hr post PCI. Worsening renal function (WRF) was defined as an increase in the serum creatinine level of \u22650.3\u2009mg\/dl from baseline after PCI.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>This study included 106 lesions from 81 patients. Forty\u2010eight (45%) lesions were Type C lesions. Successful noncontrast PCI was performed in 95 (90%) lesions. CI\u2010AKI, coronary perforation, no\/slow flow, and periprocedural death were observed in 4 (5%), 0, 9 (11%), and 0 patients, respectively. The follow\u2010up period was 348 (190\u2013492) days. Six\u2010month WRF was observed in 18 individuals (22%). While successful noncontrast PCI was not associated with the incidence of CI\u2010AKI, successful noncontrast PCI was inversely associated with WRF (hazard ratio, 0.28; 95% confidence interval, 0.09\u20130.90) after adjustment for renal function.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The present study suggests that noncontrast PCI is feasible and can be safely performed in ACS patients with complex lesions.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccd.28958","type":"journal-article","created":{"date-parts":[[2020,5,8]],"date-time":"2020-05-08T22:13:53Z","timestamp":1588976033000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Feasibility and safety of noncontrast percutaneous coronary intervention in patients with complicated acute coronary syndrome"],"prefix":"10.1002","volume":"96","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7914-8256","authenticated-orcid":false,"given":"Satoshi","family":"Higuchi","sequence":"first","affiliation":[{"name":"Department of Cardiology Kyorin University School of Medicine  Mitaka Japan"},{"name":"Department of Emergency and General Medicine Kyorin University School of Medicine  Mitaka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yusuke","family":"Kabeya","sequence":"additional","affiliation":[{"name":"Division of General Internal Medicine, Department of Internal Medicine Tokai University  Isehara Japan"},{"name":"Department of Home Care Medicine Sowa Hospital  Sagamihara Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshio","family":"Nishina","sequence":"additional","affiliation":[{"name":"Department of Cardiology Kyorin University School of Medicine  Mitaka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yusuke","family":"Miura","sequence":"additional","affiliation":[{"name":"Department of Cardiology Kyorin University School of Medicine  Mitaka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hideaki","family":"Yoshino","sequence":"additional","affiliation":[{"name":"Department of Cardiology Kyorin University School of Medicine  Mitaka 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