{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T20:21:38Z","timestamp":1777580498370,"version":"3.51.4"},"reference-count":20,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2020,6,1]],"date-time":"2020-06-01T00:00:00Z","timestamp":1590969600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2021,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>We aimed to evaluate the 1\u2010year outcomes of three everolimus\u2010eluting stents (EES) for complex percutaneous coronary intervention (PCI).<\/jats:p><\/jats:sec><jats:sec><jats:title>Background<\/jats:title><jats:p>It is controversial whether contemporary bioresorbable\u2010polymer drug\u2010eluting stents (BP\u2010DES) are associated with better outcomes compared with durable\u2010polymer DES (DP\u2010DES).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Patients undergoing PCI with cobalt\u2010chromium (CoCr)\u2010DP\u2010EES (Xience), platinum\u2010chromium (PtCr)\u2010DP\u2010EES (Promus), or PtCr\u2010BP\u2010EES (Synergy) at one high\u2010volume institution between 2015 and 2017 were included. The primary endpoint was 1\u2010year major adverse cardiac events (MACE), a composite of death, myocardial infarction, and target\u2010vessel revascularization. Associations were also examined in patients undergoing complex PCI. Multivariable analysis was conducted to adjust for baseline differences across groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>We included <jats:italic>n<\/jats:italic>\u00a0=\u20095,446 patients (CoCr\u2010DP\u2010EES, <jats:italic>n<\/jats:italic>\u00a0=\u20093,177; PtCr\u2010DP\u2010EES, <jats:italic>n<\/jats:italic>\u00a0=\u20091,555; PtCr\u2010BP\u2010EES, <jats:italic>n<\/jats:italic>\u00a0=\u2009714). Patients treated with PtCr\u2010BP\u2010EES had higher comorbidity burden and procedural complexity. At 1\u2009year, MACE rates were 8.9% for CoCr\u2010DP\u2010EES versus 8.9% for PtCr\u2010DP\u2010EES versus 8.6% for PtCr\u2010BP\u2010EES (<jats:italic>p<\/jats:italic>\u00a0=\u2009.97). The incidence of definite\/probable stent thrombosis (ST) was also similar (0.6 vs. 0.4 vs. 0.3%, <jats:italic>p<\/jats:italic>\u00a0=\u2009.69). Complex PCI was performed in <jats:italic>n<\/jats:italic>\u00a0=\u20092,894\/5,446 (53.1%). At 1\u2009year, MACE rates were 11.5 versus 10.7 versus 10.3%, respectively (<jats:italic>p<\/jats:italic>\u00a0=\u2009.83). The incidence of definite\/probable ST was also similar (0.9 vs. 0.3 vs. 0.3%, <jats:italic>p<\/jats:italic>\u00a0=\u2009.22). On multivariable analysis, stent type was not an independent predictor of MACE either in the overall or in the complex PCI population.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>We observed comparable 1\u2010year rates of MACE and definite\/probable ST in patients undergoing PCI with CoCr\u2010DP\u2010EES, PtCr\u2010DP\u2010EES, and PtCr\u2010BP\u2010EES. Results were unchanged among patients undergoing complex PCI. Future multicenter randomized studies should confirm and extend our findings.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccd.28996","type":"journal-article","created":{"date-parts":[[2020,6,1]],"date-time":"2020-06-01T12:17:12Z","timestamp":1591013832000},"page":"1341-1351","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["One\u2010year outcomes of patients undergoing complex percutaneous coronary intervention with three contemporary drug\u2010eluting stents"],"prefix":"10.1002","volume":"97","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9758-0360","authenticated-orcid":false,"given":"Lorenzo","family":"Azzalini","sequence":"first","affiliation":[{"name":"The Zena and Michael A. Wiener Cardiovascular Institute Icahn School of Medicine at Mount Sinai  New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Usman","family":"Baber","sequence":"additional","affiliation":[{"name":"The Zena and Michael A. Wiener Cardiovascular Institute Icahn School of Medicine at Mount Sinai  New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gurpreet S.","family":"Johal","sequence":"additional","affiliation":[{"name":"The Zena and Michael A. Wiener Cardiovascular Institute Icahn School of Medicine at Mount Sinai  New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Serdar","family":"Farhan","sequence":"additional","affiliation":[{"name":"The Zena and Michael A. Wiener Cardiovascular Institute Icahn School of Medicine at Mount Sinai  New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nitin","family":"Barman","sequence":"additional","affiliation":[{"name":"The Zena and Michael A. Wiener Cardiovascular Institute Icahn School of Medicine at Mount Sinai  New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vishal","family":"Kapur","sequence":"additional","affiliation":[{"name":"The Zena and Michael A. Wiener Cardiovascular Institute Icahn School of Medicine at Mount Sinai  New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Choudhury","family":"Hasan","sequence":"additional","affiliation":[{"name":"The Zena and Michael A. Wiener Cardiovascular Institute Icahn School of Medicine at Mount Sinai  New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pooja","family":"Vijay","sequence":"additional","affiliation":[{"name":"The Zena and Michael A. Wiener Cardiovascular Institute Icahn School of Medicine at Mount Sinai  New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vaishvi","family":"Jhaveri","sequence":"additional","affiliation":[{"name":"The Zena and Michael A. Wiener Cardiovascular Institute Icahn School of Medicine at Mount Sinai  New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5546-262X","authenticated-orcid":false,"given":"Roxana","family":"Mehran","sequence":"additional","affiliation":[{"name":"The Zena and Michael A. Wiener Cardiovascular Institute Icahn School of Medicine at Mount Sinai  New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7189-3307","authenticated-orcid":false,"given":"Annapoorna S.","family":"Kini","sequence":"additional","affiliation":[{"name":"The Zena and Michael A. Wiener Cardiovascular Institute Icahn School of Medicine at Mount Sinai  New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1888-0793","authenticated-orcid":false,"given":"Samin K.","family":"Sharma","sequence":"additional","affiliation":[{"name":"The Zena and Michael A. 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