{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T15:24:16Z","timestamp":1761578656888,"version":"3.40.5"},"reference-count":8,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2020,5,30]],"date-time":"2020-05-30T00:00:00Z","timestamp":1590796800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2021,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>COVID\u201019 is a new viral infection that has a significant impact on global health and economy. Because of its rapid spread worldwide, it may influence the prognosis of other medical conditions, such as ST\u2010segment elevation myocardial infarction (STEMI). We report a case of a 58\u2010year female patient admitted with an infero\u2010posterior STEMI on the background of recently positive COVID\u201019 swab. Reperfusion was attempted through primary PCI but unfortunately failed to restore coronary blood flow due to massive thrombotic burden despite several attempts of balloon dilatation and aspiration thrombectomy. She sadly died later on because of hemodynamic deterioration. This scenario raises concerns about Neutrophil Extracellular Traps (NETS) which might potentially have propagated inflammation and thrombosis via platelets' aggregation leading to enhanced coagulopathy and massive coronary thrombosis. Therefore, we suggest primary PCI as the first\u2010choice of revascularization in patients with combined COVID\u201019 and STEMI. Additionally, we emphasize on the importance of using the potent new generation P2Y12 inhibitors along with GPIIb\/IIIa inhibitors in every STEMI patient with COVID\u201019 to achieve favorable conditions for primary PCI as well as favorable outcomes after stent implantation.<\/jats:p>","DOI":"10.1002\/ccd.29050","type":"journal-article","created":{"date-parts":[[2020,5,30]],"date-time":"2020-05-30T18:38:46Z","timestamp":1590863926000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Massive coronary thrombosis caused primary percutaneous coronary intervention to fail in a COVID\u201019 patient with ST\u2010elevation myocardial infarction"],"prefix":"10.1002","volume":"97","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3468-7640","authenticated-orcid":false,"given":"Sherif","family":"Seif","sequence":"first","affiliation":[{"name":"Cardiology Department, Faculty of Medicine Tanta University  Tanta Egypt"},{"name":"Cardiology Department Royal Albert Edward Infirmary, Wrightington, Wigan and Leigh NHS Foundation Trust  Wigan UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2059-8447","authenticated-orcid":false,"given":"Ahmed","family":"Ayuna","sequence":"additional","affiliation":[{"name":"Cardiology Department Salford Royal NHS Foundation Trust  Salford UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abhishek","family":"Kumar","sequence":"additional","affiliation":[{"name":"Cardiology Department Royal Albert Edward Infirmary, Wrightington, Wigan and Leigh NHS Foundation Trust  Wigan UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John","family":"Macdonald","sequence":"additional","affiliation":[{"name":"Cardiology Department Salford Royal NHS Foundation Trust  Salford UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,5,30]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41569-020-0360-5"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamacardio.2020.1105"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCOUTCOMES.120.006631"},{"issue":"11","key":"e_1_2_5_5_1","article-title":"Neutropil extracellular traps in COVID\u201019","volume":"5","author":"Zuo Y","year":"2020","journal-title":"JCI Inshight"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1515\/cclm-2020-0188"},{"issue":"2","key":"e_1_2_5_7_1","first-page":"E241","article-title":"Insights for increased risk of failed fibrinolytic therapy and stent thrombosis associated with COVID\u201019 in ST\u2010segment elevation myocardial infarction patients","volume":"97","author":"Lacour T","year":"2020","journal-title":"Catheter Cardiovasc Interv"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2796.1989.tb00084.x"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa041747"}],"container-title":["Catheterization and Cardiovascular Interventions"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fccd.29050","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccd.29050","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ccd.29050","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccd.29050","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T20:59:45Z","timestamp":1693601985000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccd.29050"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,5,30]]},"references-count":8,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2021,4]]}},"alternative-id":["10.1002\/ccd.29050"],"URL":"https:\/\/doi.org\/10.1002\/ccd.29050","archive":["Portico"],"relation":{},"ISSN":["1522-1946","1522-726X"],"issn-type":[{"type":"print","value":"1522-1946"},{"type":"electronic","value":"1522-726X"}],"subject":[],"published":{"date-parts":[[2020,5,30]]},"assertion":[{"value":"2020-05-09","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-05-16","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-05-30","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}