{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,13]],"date-time":"2025-05-13T14:41:31Z","timestamp":1747147291543,"version":"3.40.5"},"reference-count":16,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2020,6,22]],"date-time":"2020-06-22T00:00:00Z","timestamp":1592784000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","award":["2019R1A2C3003547"],"award-info":[{"award-number":["2019R1A2C3003547"]}],"id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2021,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aims<\/jats:title><jats:p>The proper timing and indication of revascularization for a non\u2010culprit artery in patients with ST\u2010segment elevation myocardial infarction (STEMI) and multivessel disease (MVD) without cardiogenic shock remains controversial.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods and Results<\/jats:title><jats:p>This multicenter study included patients with STEMI and MVD without cardiogenic shock. Data were analyzed at 3\u2009years according to the percutaneous coronary intervention (PCI) strategy: immediate multivessel revascularization (MVR) (<jats:italic>n<\/jats:italic>\u00a0=\u00a0351), stepwise MVR (<jats:italic>n<\/jats:italic>\u00a0=\u00a0510), and culprit\u2010only PCI (<jats:italic>n<\/jats:italic>\u00a0=\u00a01,142). The primary outcome was all\u2010cause mortality. The stepwise MVR group had a lower risk of all\u2010cause death. The results were consistent after multivariate regression, propensity\u2010score matching, inverse probability weighting, and Bayesian proportional hazards modeling. In subgroup analyses stratified by the Global Registry of Acute Coronary Events score, stepwise MVR also lowered the risk of all\u2010cause death compared to culprit\u2010only PCI and immediate MVR in high risk patients but not in patients at low to intermediate risk.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>In patients with STEMI and MVD without cardiogenic shock, in\u2010hospital stepwise MVR was associated with a lower risk of all\u2010cause death than culprit\u2010only PCI or immediate MVR, particularly in the high\u2010risk subgroup.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccd.29062","type":"journal-article","created":{"date-parts":[[2020,6,22]],"date-time":"2020-06-22T17:14:35Z","timestamp":1592846075000},"page":"1151-1159","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Benefit of a staged in\u2010hospital revascularization strategy in hemodynamically stable patients with ST\u2010segment elevation myocardial infarction and multivessel disease: Analyses by risk stratification"],"prefix":"10.1002","volume":"97","author":[{"given":"Min Chul","family":"Kim","sequence":"first","affiliation":[{"name":"Department of Cardiology Chonnam National University Hospital, Chonnam National University Medical School  Gwangju Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"SungA","family":"Bae","sequence":"additional","affiliation":[{"name":"Department of Cardiology Chonnam National University Hospital, Chonnam National University Medical School  Gwangju Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2022-9366","authenticated-orcid":false,"given":"Youngkeun","family":"Ahn","sequence":"additional","affiliation":[{"name":"Department of Cardiology Chonnam National University Hospital, Chonnam National University Medical School  Gwangju Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Doo Sun","family":"Sim","sequence":"additional","affiliation":[{"name":"Department of Cardiology Chonnam National University Hospital, Chonnam National University Medical School  Gwangju Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Young Joon","family":"Hong","sequence":"additional","affiliation":[{"name":"Department of Cardiology Chonnam National University Hospital, Chonnam National University Medical School  Gwangju Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3186-0770","authenticated-orcid":false,"given":"Ju Han","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Cardiology Chonnam National University Hospital, Chonnam National University Medical School  Gwangju Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Myung Ho","family":"Jeong","sequence":"additional","affiliation":[{"name":"Department of Cardiology Chonnam National University Hospital, Chonnam National University Medical School  Gwangju Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0847-5329","authenticated-orcid":false,"given":"Hyo\u2010Soo","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Cardiology Seoul National University Hospital  Seoul Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shung Chull","family":"Chae","sequence":"additional","affiliation":[{"name":"Department of Cardiology Kyungpook National University Hospital  Daegu Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kwang Soo","family":"Cha","sequence":"additional","affiliation":[{"name":"Department of Cardiology Pusan National University Hospital  Busan Republic of 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