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We present a case of an 88\u2010year\u2010old female with symptomatic, severe AS, and LVOT obstruction with systolic anterior motion (SAM) of the mitral leaflet in whom alcohol septal ablation was contraindicated secondary to a chronic total occlusion of the right coronary artery that filled retrograde via septal collaterals. MitraClip at the time of TAVR was successfully performed to treat SAM with subsequent stabilization of LVOT gradients despite treatment of the patient's AS. This novel approach may represent a feasible option to prevent hemodynamic complications after TAVR in patients with significant LVOT obstruction secondary to SAM and AS.<\/jats:p>","DOI":"10.1002\/ccd.29100","type":"journal-article","created":{"date-parts":[[2020,6,27]],"date-time":"2020-06-27T09:26:42Z","timestamp":1593250002000},"page":"369-372","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["The use of <scp>MitraClip<\/scp> to prevent <scp>posttranscatheter<\/scp> aortic valve replacement left ventricular \u201csuicide\u201d"],"prefix":"10.1002","volume":"97","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4905-2157","authenticated-orcid":false,"given":"Michael F.","family":"Bode","sequence":"first","affiliation":[{"name":"Division of Cardiology, Department of Medicine Lahey Hospital and Medical Center  Burlington Massachusetts"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andaleeb A.","family":"Ahmed","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology Lahey Hospital and Medical Center  Burlington Massachusetts"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Suzanne J.","family":"Baron","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department of Medicine Lahey Hospital and Medical Center  Burlington Massachusetts"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sherif B.","family":"Labib","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department of Medicine Lahey Hospital and Medical Center  Burlington Massachusetts"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gautam","family":"Gadey","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department of Medicine Lahey Hospital and Medical Center  Burlington 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