{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,16]],"date-time":"2026-01-16T17:30:49Z","timestamp":1768584649936,"version":"3.49.0"},"reference-count":36,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2020,7,23]],"date-time":"2020-07-23T00:00:00Z","timestamp":1595462400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2021,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>This study sought to determine the impact of baseline chronic kidney disease (CKD) on in\u2010hospital outcomes of transcatheter mitral valve repair with MitraClip (MC).<\/jats:p><\/jats:sec><jats:sec><jats:title>Background<\/jats:title><jats:p>MC is now an established treatment in high surgical risk patients. However, limited data are available on outcomes of MC in patients with baseline renal dysfunction.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The authors used data from January 2014 to December 2017 National Readmission Database to identify all patients \u226518\u2009years of age who underwent MC. International classification of diseases (ICD)\u20109 and ICD\u201010 codes were used to identify patients with no\u2010CKD, CKD (without chronic dialysis), or end\u2010stage renal disease (ESRD) on dialysis. Multivariable logistic regression models were constructed using generalized estimating equations to examine in\u2010hospital outcomes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of 13,563 patients undergoing MC, 8,935 (65.8%) had no\u2010CKD, 4,152 (30.6%) had CKD, and 476 (3.5%) had ESRD. ESRD patients compared to CKD and no\u2010CKD had significantly higher mortality (7.2% vs. 2.5% vs. 2.0%; <jats:italic>p<\/jats:italic>\u2009&lt;\u2009.001), higher incidence of bleeding, blood transfusions, and 30\u2009day all cause readmission. CKD patients compared to no\u2010CKD had significantly higher mortality (odds ratio\u20101.29; CI 1.01\u20131.65; <jats:italic>p<\/jats:italic>\u00a0=\u00a0.04), acute kidney injury (odds ratio\u20103.0; CI 2.69\u20133.34; <jats:italic>p<\/jats:italic>\u2009&lt;\u2009.001), new in\u2010hospital hemodialysis (odds ratio\u2010 2.70; CI 1.57\u20134.62; <jats:italic>p<\/jats:italic>\u2009&lt;\u2009.001), blood transfusions, 30\u2009day all cause and congestive heart failure (CHF) readmissions. In\u2010hospital stroke and cardiac tamponade did not differ between the three groups. Patients with baseline kidney disease undergoing MC had higher mortality at high volume centers compared to low volume centers. CHF was the most common cause of readmission postMC in patients with or without preprocedural kidney disease.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Patients with baseline kidney disease have worse outcomes after MC with higher readmission rates requiring careful patient selection and follow up in this population.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccd.29129","type":"journal-article","created":{"date-parts":[[2020,7,23]],"date-time":"2020-07-23T21:23:59Z","timestamp":1595539439000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Association of baseline kidney disease with outcomes of transcatheter mitral valve repair by MitraClip"],"prefix":"10.1002","volume":"97","author":[{"given":"Hitesh","family":"Raheja","sequence":"first","affiliation":[{"name":"Department of Cardiovascular Medicine Maimonides Medical Center  Brooklyn New 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Foundation  Cleveland Ohio"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1241-5030","authenticated-orcid":false,"given":"Saurav","family":"Chatterjee","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine Long Island Jewish Medical Center  Queens New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8025-9212","authenticated-orcid":false,"given":"Omar M.","family":"Abdelfattah","sequence":"additional","affiliation":[{"name":"Heart and Vascular Institute Cleveland Clinic Foundation  Cleveland Ohio"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohamed","family":"Hassanein","sequence":"additional","affiliation":[{"name":"Heart and Vascular Institute Cleveland Clinic Foundation  Cleveland Ohio"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Serge","family":"Harb","sequence":"additional","affiliation":[{"name":"Heart and 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