{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T08:27:07Z","timestamp":1789547227932,"version":"build-2803163510"},"reference-count":12,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2020,7,16]],"date-time":"2020-07-16T00:00:00Z","timestamp":1594857600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2020,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>We applied the cardiovascular angiography and interventions (SCAI) shock staging system to patients presenting with acute myocardial infarction and cardiogenic shock (AMI\u2010CS) who were enrolled in the National Cardiogenic Shock Initiative (NCSI).<\/jats:p><\/jats:sec><jats:sec><jats:title>Background<\/jats:title><jats:p>The SCAI shock staging system provides a framework for evaluation of patients with CS based on clinical and hemodynamic parameters, but has not been validated in patients with AMI\u2010CS managed with a contemporary treatment algorithm that incorporates early use of Impella.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Consecutive patients enrolled in NCSI were identified, all of whom were managed with invasive hemodynamic guidance and supported with Impella. Patients were retrospectively categorized into appropriate SCAI shock stages, and outcomes were assessed accordingly.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 300 patients were included in the analysis; 182 patients (61%) presented in Stage C shock, 25 (8%) in Stage D, and 93 (31%) in Stage E. Survival to hospital discharge was 76, 76, and 58%, respectively (<jats:italic>p<\/jats:italic> = .006). Survival was &lt;20% among patients in Stage E at 24\u2009hr, regardless of baseline stage. There was near perfect agreement in shock staging between two independent clinicians at baseline (kappa = 0.975, 95% CI, 0.95\u20131.00, <jats:italic>p<\/jats:italic>\u2009&lt;\u2009.001) and at 24\u2009hr (kappa = 0.985, 95% CI, 0.77\u20131.00, <jats:italic>p<\/jats:italic>\u2009&lt;\u2009.001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>In patients with AMI\u2010CS enrolled in NCSI, SCAI Shock classification was reproducible, and predicted survival when applied at presentation and at 24\u2009hr.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccd.29139","type":"journal-article","created":{"date-parts":[[2020,7,16]],"date-time":"2020-07-16T12:10:40Z","timestamp":1594901440000},"page":"1137-1142","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":70,"title":["<scp>SCAI<\/scp> shock classification in acute myocardial infarction: Insights from the National Cardiogenic Shock Initiative"],"prefix":"10.1002","volume":"96","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0481-9764","authenticated-orcid":false,"given":"Ivan D.","family":"Hanson","sequence":"first","affiliation":[{"name":"Department of Cardiovascular Medicine Beaumont Hospital Royal Oak  Royal Oak Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8879-6220","authenticated-orcid":false,"given":"Travis","family":"Tagami","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine Beaumont Hospital Royal Oak  Royal Oak Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ramy","family":"Mando","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine Beaumont Hospital Royal Oak  Royal Oak Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdalla","family":"Kara Balla","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine Beaumont Hospital Royal Oak  Royal Oak Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simon R.","family":"Dixon","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine Beaumont Hospital Royal Oak  Royal Oak Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven","family":"Timmis","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine Beaumont Hospital Royal Oak  Royal Oak Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven","family":"Almany","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine Beaumont Hospital Royal Oak  Royal Oak Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Srihari S.","family":"Naidu","sequence":"additional","affiliation":[{"name":"Westchester Medical Center and New York Medical College  Valhalla New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7754-9953","authenticated-orcid":false,"given":"David","family":"Baran","sequence":"additional","affiliation":[{"name":"Division of Cardiology Sentara Heart Hospital  Norfolk Virginia USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alejandro","family":"Lemor","sequence":"additional","affiliation":[{"name":"Division of Cardiology Henry Ford Hospital  Detroit Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah","family":"Gorgis","sequence":"additional","affiliation":[{"name":"Division of Cardiology Henry Ford Hospital  Detroit Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William","family":"O'Neill","sequence":"additional","affiliation":[{"name":"Division of Cardiology Henry Ford Hospital  Detroit Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3486-6753","authenticated-orcid":false,"given":"Mir B.","family":"Basir","sequence":"additional","affiliation":[{"name":"Division of Cardiology Henry Ford Hospital  Detroit Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"National Cardiogenic Shock Investigators","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,7,16]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2015.11.048"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.28329"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2016.11.037"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2020.0254"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.118.036614"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.28307"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.27427"},{"key":"e_1_2_6_9_1","first-page":"81","article-title":"Combat' approach to cardiogenic shock","volume":"13","author":"Truesdell AG","year":"2018","journal-title":"Interv 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