{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,16]],"date-time":"2026-02-16T09:12:03Z","timestamp":1771233123849,"version":"3.50.1"},"reference-count":16,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2020,8,8]],"date-time":"2020-08-08T00:00:00Z","timestamp":1596844800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Jennifer and Robert McNeil"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2021,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>This study sought to investigate the incidence and outcomes of surgical bailout (SB) after transcatheter mitral valve repair (TMVr) with MitraClip.<\/jats:p><\/jats:sec><jats:sec><jats:title>Background<\/jats:title><jats:p>TMVr poses a risk of serious procedural complications, possibly requiring urgent open surgery for SB. However, little is known about the risk of SB cases after TMVr.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We retrospectively identified patients who underwent TMVr using the Nationwide Readmissions Database 2014\u20132017. SB was defined as open thoracotomy for heart and aorta during the same hospitalization. Annual hospital volume was defined as the annual number of TMVr cases in each hospital in each year.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Among 15,032 eligible patients, SB was required in 214 (1.42%), of whom 134 (62.6%) underwent mitral valve surgery (113 replacements; 21 repairs). The incidence of SB was decreasing significantly over the 4\u2009years (5.26% in 2014; 0.43% in 2017; <jats:italic>p<\/jats:italic><jats:sub>trend<\/jats:sub>\u2009&lt;\u2009.001). There was a significant nonlinear, inverse association of annual hospital volume with the incidence of SB. In\u2010hospital death (15.0 vs. 2.1%; <jats:italic>p<\/jats:italic>\u2009&lt;\u2009.001) and other in\u2010hospital adverse events were significantly more frequent in patients with than without SB, whereas the 30\u2010day readmission rate was similar (13.2 vs. 15.1%; <jats:italic>p<\/jats:italic> = .572). After adjustment for patient and hospital characteristics, SB was significantly associated with higher in\u2010hospital mortality (odds ratio = 6.67, 95% confidence interval = 4.35, 10.23, <jats:italic>p<\/jats:italic>\u2009&lt;\u2009.001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>This study suggests that although the incidence of SB after TMVr is decreasing, SB is required more frequently in lower\u2010volume hospitals and carries high in\u2010hospital mortality. Further efforts are needed to understand the reasons for SB and improve outcomes in patients needing SB.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccd.29153","type":"journal-article","created":{"date-parts":[[2020,8,8]],"date-time":"2020-08-08T11:01:20Z","timestamp":1596884480000},"page":"335-341","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Incidence and short\u2010term outcomes of surgical bailout after transcatheter mitral valve repair with the <scp>MitraClip<\/scp> system"],"prefix":"10.1002","volume":"97","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2172-6447","authenticated-orcid":false,"given":"Toshiaki","family":"Isogai","sequence":"first","affiliation":[{"name":"Department of Cardiovascular Medicine Heart and Vascular Institute, Cleveland Clinic  Cleveland Ohio"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anas M.","family":"Saad","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine Heart and Vascular Institute, Cleveland Clinic  Cleveland Ohio"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shashank","family":"Shekhar","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine Heart and Vascular Institute, Cleveland Clinic  Cleveland Ohio"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keerat Rai","family":"Ahuja","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine Heart and Vascular Institute, Cleveland Clinic  Cleveland Ohio"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8025-9212","authenticated-orcid":false,"given":"Omar M.","family":"Abdelfattah","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine Heart and Vascular Institute, Cleveland Clinic  Cleveland Ohio"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0218-3317","authenticated-orcid":false,"given":"Mohamed M.","family":"Gad","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine Heart and Vascular Institute, Cleveland Clinic  Cleveland Ohio"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel J.P.","family":"Burns","sequence":"additional","affiliation":[{"name":"Department of Thoracic and Cardiovascular Surgery Heart and Vascular Institute, Cleveland Clinic  Cleveland Ohio"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James J.","family":"Yun","sequence":"additional","affiliation":[{"name":"Department of Thoracic and Cardiovascular Surgery Heart and Vascular Institute, Cleveland Clinic  Cleveland Ohio"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6048-7955","authenticated-orcid":false,"given":"Amar","family":"Krishnaswamy","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine Heart and Vascular Institute, Cleveland Clinic  Cleveland Ohio"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0026-3391","authenticated-orcid":false,"given":"Samir R.","family":"Kapadia","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine Heart and Vascular Institute, Cleveland Clinic  Cleveland Ohio"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,8,8]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1009355"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2013.12.062"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2017.03.011"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1806640"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2017.09.015"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2019.02.039"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.25838"},{"key":"e_1_2_8_9_1","unstructured":"Healthcare Cost and Utilization Project. NRD Overview.https:\/\/www.hcup-us.ahrq.gov\/nrdoverview.jsp."},{"key":"e_1_2_8_10_1","unstructured":"Centers for Medicare and Medicaid Services. ICD\u201010.https:\/\/www.cms.gov\/Medicare\/Coding\/ICD10\/index."},{"key":"e_1_2_8_11_1","unstructured":"Healthcare Cost and Utilization Project. Requirements for Publishing with HCUP Data.https:\/\/www.hcup-us.ahrq.gov\/db\/publishing.jsp."},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2018.08.054"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.28647"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2019.04.026"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehx713"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.mlr.0000132391.59713.0d"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.mlr.0000228018.48783.34"}],"container-title":["Catheterization and Cardiovascular Interventions"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fccd.29153","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccd.29153","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ccd.29153","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccd.29153","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,2]],"date-time":"2023-09-02T15:18:49Z","timestamp":1693667929000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccd.29153"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,8,8]]},"references-count":16,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2021,2]]}},"alternative-id":["10.1002\/ccd.29153"],"URL":"https:\/\/doi.org\/10.1002\/ccd.29153","archive":["Portico"],"relation":{},"ISSN":["1522-1946","1522-726X"],"issn-type":[{"value":"1522-1946","type":"print"},{"value":"1522-726X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,8,8]]},"assertion":[{"value":"2020-06-30","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-07-05","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-08-08","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}