{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,13]],"date-time":"2025-05-13T14:41:58Z","timestamp":1747147318950,"version":"3.40.5"},"reference-count":24,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2020,8,26]],"date-time":"2020-08-26T00:00:00Z","timestamp":1598400000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2021,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>The present study aims to analyze the angiographic anti\u2010restenotic performance of durable polymer everolimus\u2010eluting stents (EES) for the treatment of in\u2010stent restenosis (ISR) in daily practice.<\/jats:p><\/jats:sec><jats:sec><jats:title>Background<\/jats:title><jats:p>Randomized data is available supporting the use of drug\u2010coated balloons and drug\u2010eluting stents for the treatment of ISR; however, additional real\u2010world data including angiographic follow\u2010up is needed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Patients who underwent EES\u2010implantation for the treatment of drug\u2010eluting stent ISR and attended for a 6\u20138\u00a0months angiographic surveillance were analyzed. Off\u2010line assessment of the angiograms was conducted at a central quantitative coronary angiographic core laboratory.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 426 patients with ISR were treated with EES and had undergone angiographic follow\u2010up. The mean age was 66.8\u2009\u00b1\u20099.9\u2009years and 27.5% suffered from diabetes. A total of 459 lesions were treated. The diameter stenosis decreased from 64.3\u2009\u00b1\u200919.1% (preprocedural) to 12.0\u2009\u00b1\u20096.4% (postprocedural). At 6\u20138\u00a0months angiographic follow\u2010up, the in\u2010segment diameter stenosis was 38.3\u2009\u00b1\u200921.7% and the in\u2010stent late luminal loss was 0.54\u2009\u00b1\u20090.74\u2009mm in the treated area analysis. The rate of recurrent binary restenosis was 25.7%.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>In the setting of ISR, the angiographic anti\u2010restenotic efficacy of stenting with EES is comparable to that observed in randomized clinical trials and less favorable than its performance in patients undergoing stenting for de novo disease.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccd.29225","type":"journal-article","created":{"date-parts":[[2020,8,26]],"date-time":"2020-08-26T23:48:19Z","timestamp":1598485699000},"page":"857-862","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Angiographic performance of everolimus\u2010eluting stents for the treatment of coronary in\u2010stent restenosis in daily 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