{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T13:33:08Z","timestamp":1790429588309,"version":"4.1.0"},"reference-count":27,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2020,9,14]],"date-time":"2020-09-14T00:00:00Z","timestamp":1600041600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100002336","name":"Daiichi Sankyo Company","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002336","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006520","name":"Edwards Lifesciences","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006520","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100008497","name":"Boston Scientific Corporation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008497","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004374","name":"Medtronic","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004374","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2021,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To compare safety, efficacy, and hemodynamics of transfemoral transcatheter aortic valve replacement (TAVR) using self\u2010expanding and balloon\u2010expandable transcatheter heart valves (THVs) in patients with a small aortic annulus.<\/jats:p><\/jats:sec><jats:sec><jats:title>Background<\/jats:title><jats:p>Few studies have directly compared TAVR outcomes using third\u2010generation THVs, focusing on patients with small aortic annuli.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>In a multicenter TAVR registry, we analyzed data from 576 patients with a small annulus and who underwent transfemoral TAVR using third\u2010generation THVs. Propensity score matching was used to adjust baseline clinical characteristics.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The device success rate in the overall cohort was 92.0% (Evolut R: 92.1% vs. Sapien 3:92.0%, <jats:italic>p<\/jats:italic>\u00a0=\u00a00.96). One year after TAVR, patients treated with Evolut R maintained a lower mean pressure gradient (mPG) and a higher indexed effective orifice area (iEOA) in the matched cohort {mPG: 9.0 [interquartile range (IQR): 6.0\u201311.9] vs. 12.0 [IQR: 9.9\u201316.3] mmHg, <jats:italic>p<\/jats:italic>\u2009&lt;\u2009.001; iEOA: 1.20 [IQR: 1.01\u20131.46] vs. 1.08 [IQR: 0.90\u20131.28] cm<jats:sup>2<\/jats:sup>\/m<jats:sup>2<\/jats:sup>, <jats:italic>p<\/jats:italic>\u2009&lt;\u2009.001}. However, no significant differences were reported in the incidence of severe prosthesis\u2010patient mismatch and aortic regurgitation at 1 year. Furthermore, both groups showed comparable outcomes with no differences in terms of all\u2010cause mortality (log\u2010lank test, <jats:italic>p<\/jats:italic>\u00a0=\u00a0.81).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>TAVR for patients with a small annulus using third\u2010generation THVs was associated with high device success. Evolut R seems to be superior to Sapien 3 in hemodynamic performance for patients with a small annulus and body surface area up to 1 year after TAVR. Nevertheless, all\u2010cause mortality at 1 year was similar between both groups.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccd.29259","type":"journal-article","created":{"date-parts":[[2020,9,17]],"date-time":"2020-09-17T07:21:24Z","timestamp":1600327284000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":35,"title":["Transcatheter aortic valve replacement with Evolut R versus Sapien 3 in Japanese patients with a small aortic annulus: The OCEAN\u2010TAVI registry"],"prefix":"10.1002","volume":"97","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1219-1193","authenticated-orcid":false,"given":"Hiromu","family":"Hase","sequence":"first","affiliation":[{"name":"Department of Cardiology Keio University School of Medicine  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5849-4627","authenticated-orcid":false,"given":"Nobuhiro","family":"Yoshijima","sequence":"additional","affiliation":[{"name":"Department of Cardiology Keio University School of Medicine  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryo","family":"Yanagisawa","sequence":"additional","affiliation":[{"name":"Department of Cardiology Keio University School of Medicine  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5343-0352","authenticated-orcid":false,"given":"Makoto","family":"Tanaka","sequence":"additional","affiliation":[{"name":"Department of Cardiology Keio University School of Medicine  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hikaru","family":"Tsuruta","sequence":"additional","affiliation":[{"name":"Department of Cardiology Keio University School of Medicine  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hideyuki","family":"Shimizu","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery Keio University School of Medicine  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keiichi","family":"Fukuda","sequence":"additional","affiliation":[{"name":"Department of Cardiology Keio University School of Medicine  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4501-1358","authenticated-orcid":false,"given":"Toru","family":"Naganuma","sequence":"additional","affiliation":[{"name":"New Tokyo Hospital  Matsudo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazuki","family":"Mizutani","sequence":"additional","affiliation":[{"name":"Department of Cardiology Osaka City General Hospital  Osaka 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