{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T08:48:13Z","timestamp":1771490893175,"version":"3.50.1"},"reference-count":40,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2020,10,21]],"date-time":"2020-10-21T00:00:00Z","timestamp":1603238400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2021,2]]},"abstract":"<jats:title>Abstarct<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Carotid artery stenting (CAS) is being increasingly used as an alternative revascularization procedure to carotid endarterectomy; however, subclinical ischemic cerebral lesions after CAS remain as a matter of concern. Hence, we aimed to assess the clinical utility of the CHADS<jats:sub>2<\/jats:sub> score in predicting subclinical ischemic events after CAS.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We prospectively evaluated 107 patients (mean age: 70.4\u2009\u00b1\u20096.6\u2009years, male:77) who underwent CAS for carotid artery revascularization. The patients having symptomatic transient ischemic attack or stroke after CAS were excluded. The presence of new hyperintense lesion on diffusion\u2010weighted imaging (DWI) without any neurological findings was considered as silent ischemia. Patients were classified into two groups as DWI\u2010positive and DWI\u2010negative patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Among study population, 28 patients (26.2%) had subclinical embolism. The DWI\u2010positive group had a significantly higher CHADS2 scores, older age, more frequent history of stroke, higher proportion of type III aortic arch, and longer fluoroscopy time than the DWI\u2010negative group. Increased CHADS<jats:sub>2<\/jats:sub> score was identified as one of the independent predictors of silent embolism (OR = 5.584; 95%CI: 1.516\u201320.566; <jats:italic>p<\/jats:italic> = .010), and CHADS<jats:sub>2<\/jats:sub> score higher than 2.5 predicted subclinical cerebral ischemia with a sensitivity of 72% and a specificity of 71% (AUC: 0.793; 95% CI: 0.696 \u2013 0.890; <jats:italic>p<\/jats:italic>\u2009&lt;\u2009.001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>CHADS<jats:sub>2<\/jats:sub> score was able to predict the risk of periprocedural subclinical ischemic events in CAS and might be of clinical value in the management of patients with carotid artery stenosis.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccd.29344","type":"journal-article","created":{"date-parts":[[2020,10,21]],"date-time":"2020-10-21T10:34:50Z","timestamp":1603276490000},"page":"301-309","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["The <scp>predictive<\/scp> value of <scp>CHADS2 score<\/scp> for <scp>subclinical<\/scp> cerebral ischemia <scp>after<\/scp> carotid artery stenting (from the <scp>PREVENT\u2010CAS<\/scp> trial)"],"prefix":"10.1002","volume":"97","author":[{"given":"\u00d6mer","family":"\u00c7elik","sequence":"first","affiliation":[{"name":"Department of Cardiology University of Health Sciences Turkey, Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Training and Research Hospital  Istanbul 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R\u0131za","family":"Demir","sequence":"additional","affiliation":[{"name":"Department of Cardiology University of Health Sciences Turkey, Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Training and Research Hospital  Istanbul Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yusuf","family":"Demir","sequence":"additional","affiliation":[{"name":"Department of Cardiology University of Health Sciences Turkey, Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Training and Research Hospital  Istanbul Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Begum","family":"Uygur","sequence":"additional","affiliation":[{"name":"Department of Cardiology University of Health Sciences Turkey, Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Training and Research Hospital  Istanbul Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmet 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