{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,16]],"date-time":"2026-04-16T20:37:41Z","timestamp":1776371861085,"version":"3.51.2"},"reference-count":22,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2020,12,6]],"date-time":"2020-12-06T00:00:00Z","timestamp":1607212800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2021,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>Octogenarians are a high\u2010risk group presenting for percutaneous coronary intervention (PCI). We aimed to create a 30\u2010day mortality risk model for octogenarians presenting with both acute coronary syndrome (ACS) and chronic stable angina (CSA), using comprehensive mandatory UK data submissions to the UK National database.<\/jats:p><\/jats:sec><jats:sec><jats:title>Background<\/jats:title><jats:p>Octogenarians are a high\u2010risk group presenting for percutaneous coronary intervention, and decisions on whether or not to undertake intervention in this cohort can be challenging. The increasing number of octogenarians in the general population means they represent an important high\u2010risk subgroup of patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The data group consisted of 425,897 PCI procedures undertaken in the UK between 2008 and 2012 during which time there was comprehensive data linkage to mortality via the Office of National Statistics. Of these procedures, 44,221 (10.4%) were in patients aged \u226580. These comprised the model group. Logistic regression was used to create a predictive score which ultimately consisted of the following weightings: age 80\u201389 (<jats:italic>n\u2009=<\/jats:italic>\u00a01); age\u2009&gt;\u200990 (<jats:italic>n\u2009=<\/jats:italic>\u00a02); unstable angina\/non\u2010ST\u2010elevation myocardial infraction (NSTEMI) (<jats:italic>n\u2009=<\/jats:italic>\u00a01); STEMI (<jats:italic>n\u2009=<\/jats:italic>\u00a02); creatinine &gt;200\u2009mmol\/L (<jats:italic>n\u2009=<\/jats:italic>\u00a01); preprocedural ventilation (<jats:italic>n\u2009=<\/jats:italic>\u00a01); left ventricular ejection fraction &lt;30% (<jats:italic>n\u2009=<\/jats:italic>\u00a01); cardiogenic shock (<jats:italic>n\u2009=<\/jats:italic>\u00a02). Multiple imputation was used to account for missing data.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The patient cohort was divided into a derivation (<jats:italic>n\u2009=<\/jats:italic>\u00a022,072) and a validation dataset (<jats:italic>n\u2009=<\/jats:italic>\u00a022,071). Receiver operating characteristic analyses were used to derive the area\u2010under\u2010the\u2010curve to assess properties of the score. The scoring system generated an AUC 0.83, (95% CI 0.80\u20130.85) suggesting high sensitivity and specificity. Scores of 1\u20134 were associated with good survival but scores \u22655 were associated with an estimated likelihood of death within 30\u2009days of \u226540%.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>This octogenarian risk score maybe a useful tool to determine the chance of a successful outcome in elderly patients presenting for PCI.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccd.29406","type":"journal-article","created":{"date-parts":[[2020,12,7]],"date-time":"2020-12-07T07:56:16Z","timestamp":1607327776000},"page":"1300-1307","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Percutaneous coronary intervention in octogenarians: A risk scoring system to predict 30\u2010day outcomes in the elderly"],"prefix":"10.1002","volume":"98","author":[{"given":"James","family":"Cockburn","sequence":"first","affiliation":[{"name":"Sussex Cardiac Centre Brighton and Sussex University Hospitals 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