{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,8]],"date-time":"2026-01-08T06:46:41Z","timestamp":1767854801661,"version":"3.49.0"},"reference-count":28,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2021,1,5]],"date-time":"2021-01-05T00:00:00Z","timestamp":1609804800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2021,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>There is a paucity of data regarding the outcomes of transcatheter aortic valve replacement (TAVR) versus surgical aortic valve replacement (SAVR) among solid\u2010organ transplant recipients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Temporal trends in hospitalizations for aortic valve replacement among solid\u2010organ transplant recipients were determined using the National Inpatient Sample database years 2012\u20132017. Propensity matching was conducted to compare admissions who underwent TAVR versus SAVR. The primary outcome was in\u2010hospital mortality.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The analysis included 1,730 hospitalizations for isolated AVR; 920 (53.2%) underwent TAVR and 810 (46.7%) underwent SAVR. TAVR was increasingly utilized for solid\u2010organ transplant recipients (P<jats:sub>trend<\/jats:sub> = 0.01), while there was no change in the number of SAVR procedures (P<jats:sub>trend<\/jats:sub> = 0.20). The predictors of undergoing TAVR for solid\u2010organ transplant recipients included older age, diabetes, and prior coronary artery bypass surgery, while TAVR was less likely utilized in small\u2010sized hospitals. TAVR was associated with lower in\u2010hospital mortality after matching (0.9 vs. 4.7%, odds ratio [OR] 0.19; 95% confidence interval [CI] 0.11\u20130.35, <jats:italic>p<\/jats:italic>\u2009&lt;\u2009.001) and after multivariable adjustment (OR 0.07; 95% CI 0.03\u20130.21, <jats:italic>p<\/jats:italic>\u2009&lt;\u2009.001). TAVR was associated with lower rate of acute kidney injury, acute stroke, postoperative bleeding, blood transfusion, vascular complications, discharge to nursing facilities, and shorter median length of hospital stay. There was no difference between both groups in the use of mechanical circulatory support, hemodialysis, arrhythmias, or pacemaker insertion.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This contemporary observational nationwide analysis showed that TAVR is increasingly performed among solid\u2010organ transplant recipients. Compared with SAVR, TAVR was associated with lower in\u2010hospital mortality, complications, and shorter length of stay.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccd.29426","type":"journal-article","created":{"date-parts":[[2021,1,6]],"date-time":"2021-01-06T09:48:12Z","timestamp":1609926492000},"page":"691-698","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Outcomes of transcatheter versus surgical aortic valve replacement among solid organ transplant recipients"],"prefix":"10.1002","volume":"97","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4248-781X","authenticated-orcid":false,"given":"Ayman","family":"Elbadawi","sequence":"first","affiliation":[{"name":"Department of Cardiovascular Medicine University of Texas Medical Branch  Galveston Texas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Justin","family":"Ugwu","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine University of Texas Medical Branch  Galveston Texas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9853-7591","authenticated-orcid":false,"given":"Islam Y.","family":"Elgendy","sequence":"additional","affiliation":[{"name":"Division of Cardiology Weill Cornell Medicine\u2010Qatar  Doha Qatar"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3176-6677","authenticated-orcid":false,"given":"Michael","family":"Megaly","sequence":"additional","affiliation":[{"name":"Minneapolis Heart Institute at Abbott Northwestern Hospital  Minneapolis Minnesota USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4140-8067","authenticated-orcid":false,"given":"Gbolahan O.","family":"Ogunbayo","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine University of Kentucky  Lexington Kentucky USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohamed A.","family":"Omer","sequence":"additional","affiliation":[{"name":"Minneapolis Heart Institute at Abbott Northwestern Hospital  Minneapolis Minnesota USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammed","family":"Elzeneini","sequence":"additional","affiliation":[{"name":"Division of Internal Medicine University of Florida  Gainesville Florida USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Khaled","family":"Chatila","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine University of Texas Medical Branch  Galveston Texas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karim","family":"Al\u2010Azizi","sequence":"additional","affiliation":[{"name":"Interventional Cardiology and Structural Heart Disease The Heart Hospital Baylor Plano, Baylor Scott and White Health  Plano Texas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6041-3876","authenticated-orcid":false,"given":"Sachin S.","family":"Goel","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Medicine Houston Methodist Hospital  Houston Texas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sameer","family":"Gafoor","sequence":"additional","affiliation":[{"name":"Swedish Medical Centre Heart and Vascular Institute  Seattle Washington USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,1,5]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1514616"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1008232"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2019.04.037"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.109.912170"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40472-020-00275-1"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2015.10.043"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jjcc.2013.01.016"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-200203270-00012"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2016.08.092"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2017.09.002"},{"key":"e_1_2_9_12_1","unstructured":"ElixhauserA.Clinical classifications for health policy research: version 2: software and User's guide: US Department of Health and Human Services Public Health Service Agency for Health Care Policy and Research;1996."},{"key":"e_1_2_9_13_1","unstructured":"CostHandProjectU.Introduction to the HCUP national inpatient sample (NIS). 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