{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T12:00:39Z","timestamp":1782993639507,"version":"3.54.5"},"reference-count":25,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2021,2,14]],"date-time":"2021-02-14T00:00:00Z","timestamp":1613260800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2021,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Valve\u2010in\u2010valve transcatheter aortic valve replacement (ViV\u2010TAVR) is an emerging alternative to re\u2010do surgery. However, the challenge of coronary access (CA) following ViV\u2010TAVR is a potential limitation as TAVR expands to younger lower\u2010risk populations.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>Using post\u2010implantation computed tomography (CT) scans to evaluate the geometrical relationship between coronary ostia and valve frame in patients undergoing ViV\u2010TAVR with the ACURATE neo valve.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Post\u2010implant CT scans of 18 out of 20 consecutive patients treated with the ACURATE neo valve were analyzed. Coronary ostia location in relation to the highest plane (HP) (highest point of the ACURATE neo or surgical valve) was determined. Ostia located below the highest plan were further subclassified according to the gap available between the transcatheter heart valve frame and ostium (transcatheter\u2010to\u2010coronary [TTC] distance). The impact implantation depth has on these geometrical relationships was evaluated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 21 out of 36 coronary ostia (58%) were located below the level of the HP with the left coronary artery (36%) more likely to be affected than the right (22%). Further sub\u2010classification of these ostia revealed a large (&gt;6\u2009mm), moderate (4\u20136\u2009mm), and small (&lt;4\u2009mm) TTC distance in 57% (12\/21), 38% (8\/21), and in 6% (1\/18) of cases, respectively. At an implantation depth &lt;4\u2009mm compared to &gt;4\u2009mm, all ostia were located below the HP with no difference in post\u2010procedural mean gradients (14.5\u2009mmHg\u2009\u00b1\u20094.7 vs. 12.6\u2009mmHg\u2009\u00b1\u20095.8; <jats:italic>p<\/jats:italic>\u00a0=\u00a0.5, 95%CI 3.8\u20137.5).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>CA following ACURATE neo implantation for ViV\u2010TAVR could potentially be challenging in a significant proportion of patients and specific consideration should be given to the implantation depth.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccd.29503","type":"journal-article","created":{"date-parts":[[2021,2,17]],"date-time":"2021-02-17T04:59:50Z","timestamp":1613537990000},"page":"595-604","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Computed tomography analysis of coronary ostia location following valve\u2010in\u2010valve transcatheter aortic valve replacement with the <scp>ACURATE<\/scp> neo valve: Implications for coronary access"],"prefix":"10.1002","volume":"98","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4455-2865","authenticated-orcid":false,"given":"Arif A.","family":"Khokhar","sequence":"first","affiliation":[{"name":"Interventional Cardiology Unit GVM Care &amp; Research Maria Cecilia Hospital  Cotignola Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandra","family":"Laricchia","sequence":"additional","affiliation":[{"name":"Interventional Cardiology Unit GVM Care &amp; Research Maria Cecilia Hospital  Cotignola Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0135-5551","authenticated-orcid":false,"given":"Francesco","family":"Ponticelli","sequence":"additional","affiliation":[{"name":"Interventional Cardiology Unit GVM Care &amp; Research Maria Cecilia Hospital  Cotignola Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0799-7478","authenticated-orcid":false,"given":"Won\u2010Keun","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Cardiology and Cardiac Surgery Kerckhoff Heart and Lung Center  Bad Nauheim Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco","family":"Gallo","sequence":"additional","affiliation":[{"name":"Interventional Cardiology Unit GVM Care &amp; Research Maria Cecilia Hospital  Cotignola Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Damiano","family":"Regazzoli","sequence":"additional","affiliation":[{"name":"Cardio Center Humanitas Research Hospital  Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4055-5062","authenticated-orcid":false,"given":"Marco","family":"Toselli","sequence":"additional","affiliation":[{"name":"Interventional Cardiology Unit GVM Care &amp; Research Maria Cecilia Hospital  Cotignola Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6421-1120","authenticated-orcid":false,"given":"Alessandro","family":"Sticchi","sequence":"additional","affiliation":[{"name":"Interventional Cardiology Unit GVM Care &amp; Research Maria Cecilia Hospital  Cotignola Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4731-9225","authenticated-orcid":false,"given":"Rossella","family":"Ruggiero","sequence":"additional","affiliation":[{"name":"Interventional Cardiology Unit GVM Care &amp; Research Maria Cecilia Hospital  Cotignola Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7325-4229","authenticated-orcid":false,"given":"Alberto","family":"Cereda","sequence":"additional","affiliation":[{"name":"Interventional Cardiology Unit GVM Care &amp; Research Maria Cecilia Hospital  Cotignola Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adriana","family":"Zlahoda\u2010Huzior","sequence":"additional","affiliation":[{"name":"Department of Measurement and Electronics Poland and AGH University of Science and Technology  Krakow Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Fisicaro","sequence":"additional","affiliation":[{"name":"Interventional Cardiology Unit GVM Care &amp; Research Maria Cecilia Hospital  Cotignola Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ilja","family":"Gardi","sequence":"additional","affiliation":[{"name":"Interventional Cardiology Unit GVM Care &amp; Research Maria Cecilia Hospital  Cotignola Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"Mangieri","sequence":"additional","affiliation":[{"name":"Interventional Cardiology Unit GVM Care &amp; Research Maria Cecilia Hospital  Cotignola Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernhard","family":"Reimers","sequence":"additional","affiliation":[{"name":"Cardio Center Humanitas Research Hospital  Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dariusz","family":"Dudek","sequence":"additional","affiliation":[{"name":"Institute of Cardiology Jagiellonian University Medical College  Krakow Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"Colombo","sequence":"additional","affiliation":[{"name":"Interventional Cardiology Unit GVM Care &amp; Research Maria Cecilia Hospital  Cotignola Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3391-9860","authenticated-orcid":false,"given":"Francesco","family":"Giannini","sequence":"additional","affiliation":[{"name":"Interventional Cardiology Unit GVM Care &amp; Research Maria Cecilia Hospital  Cotignola Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,2,14]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2017.03.011"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2017.02.057"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/joic.12520"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2019.10.030"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2015.01.052"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2013.01.096"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2018.09.001"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2020.01.229"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2020.01.202"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2020.01.216"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1136\/heartjnl-2017-312422"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2018.04.039"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2012.09.002"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcmg.2018.12.003"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehx455"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2018.01.057"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2019.02.020"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.4244\/EIJ-D-19-01094"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcct.2017.08.003"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2019.07.042"},{"key":"e_1_2_8_22_1","doi-asserted-by":"crossref","unstructured":"Eisenhauer AC Hadjipetrou P Piemonte TC. Balloon aortic valvuloplasty revisited: The role of the Inoue balloon and transseptal antegrade approach. Catheter Cardiovasc Interv 2000;50(4):484\u2010491.https:\/\/doi.org\/10.1002\/1522\u2010726X(200008)50:4<484::AID\u2010CCD25>3.0.CO;2\u2010W.","DOI":"10.1002\/1522-726X(200008)50:4<484::AID-CCD25>3.0.CO;2-W"},{"key":"e_1_2_8_23_1","doi-asserted-by":"crossref","unstructured":"Sakata Y Syed Z Salinger MH Feldman T. Percutaneous balloon aortic valvuloplasty: Antegrade transseptal vs. conventional retrograde transarterial approach. Catheter Cardiovasc Interv. 2005;64(3):314\u2010321.https:\/\/doi.org\/10.1002\/ccd.20300.","DOI":"10.1002\/ccd.20300"},{"key":"e_1_2_8_24_1","doi-asserted-by":"crossref","unstructured":"Abdou SM Chen YL Wu CJ Lau KW Hung JS. Concurrent antegrade transseptal inoue\u2010balloon mitral and aortic valvuloplasty. Catheter Cardiovasc Interv. 2013;82(5):E712\u2010E717.https:\/\/doi.org\/10.1002\/ccd.24770.","DOI":"10.1002\/ccd.24770"},{"key":"e_1_2_8_25_1","doi-asserted-by":"crossref","unstructured":"Yano M Saito N Watanabe S et al. First clinical experience of the looped Inoue balloon technique for antegrade percutaneous balloon aortic valvuloplasty. Heart Vessels. 2015;30(6):830\u2010834.https:\/\/doi.org\/10.1007\/s00380-014-0552-1.","DOI":"10.1007\/s00380-014-0552-1"},{"key":"e_1_2_8_26_1","unstructured":"Sakata Y Matsubara K Tamiya S Hayama Y Usui K. The efficacy and safety of antegrade inoue\u2010balloon aortic valvuloplasty to treat calcific critical aortic stenosis. J Invasive Cardiol. 2015;27(8):373\u2010380. PMID: 26232015"}],"container-title":["Catheterization and Cardiovascular Interventions"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccd.29503","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ccd.29503","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccd.29503","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,22]],"date-time":"2023-08-22T12:14:50Z","timestamp":1692706490000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccd.29503"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,2,14]]},"references-count":25,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2021,9]]}},"alternative-id":["10.1002\/ccd.29503"],"URL":"https:\/\/doi.org\/10.1002\/ccd.29503","archive":["Portico"],"relation":{},"ISSN":["1522-1946","1522-726X"],"issn-type":[{"value":"1522-1946","type":"print"},{"value":"1522-726X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,2,14]]},"assertion":[{"value":"2020-09-14","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-12-10","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-02-14","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}