{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T22:08:24Z","timestamp":1791410904123,"version":"4.3.3"},"reference-count":35,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2021,2,8]],"date-time":"2021-02-08T00:00:00Z","timestamp":1612742400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2021,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>There is a rising trend for transcatheter aortic valve implantation (TAVI) in bicuspid aortic stenosis patients. Data on the use of self\u2010expandable (SEV) vs. balloon\u2010expandable (BEV) valves in these patients are scarce. Therefore, we systematically compared clinical outcomes in bicuspid aortic stenosis patients treated with SEV and BEV.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Data were extracted from PubMed\/MEDLINE, EMBASE, CENTRAL\/CCTR, <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"http:\/\/clinicaltrials.gov\">ClinicalTrials.gov<\/jats:ext-link>, SciELO, LILACS, Google Scholar and reference lists of relevant articles. Eight studies published from 2013 to 2020 including a total of 1,080 patients (BEV: n\u00a0=\u00a0620; SEV: n\u00a0=\u00a0460) were selected. Primary endpoints were procedural, 30\u2010day and 1\u2010year mortality. Secondary endpoints were new pacemaker implantation, annular rupture, coronary obstruction, moderate\u2010to\u2010severe paravalvular leak, need of second valve, stroke and acute kidney injury.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>We found no statistically significant difference in mortality between patients treated with BEV vs. SEV during index procedure, at 30\u2009days and at 1\u00a0year. BEVs showed a statistically significant higher risk of annulus rupture (2.5%) in comparison with SEV (0%) (OR 5.81 [95% CI, 3.78\u20138.92], <jats:italic>p<\/jats:italic>\u2009&lt;\u2009.001). New generation BEVs were also associated with significantly less paravalvular leak when compared to new generation SEVs (OR 0.08 [95% CI, 0.02\u20130.35], <jats:italic>p<\/jats:italic>\u00a0=\u00a0.001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>This meta\u2010analysis of observational studies of TAVI for bicuspid valves, showed no difference in short\u2010 and mid\u2010term TAVI mortality with BEVs and SEVs. BEVs presented a higher risk of annular rupture in comparison with SEV.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccd.29538","type":"journal-article","created":{"date-parts":[[2021,2,9]],"date-time":"2021-02-09T12:53:12Z","timestamp":1612875192000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":24,"title":["Balloon versus self\u2010expandable transcatheter aortic valve implantation for bicuspid aortic valve stenosis: A meta\u2010analysis of observational studies"],"prefix":"10.1002","volume":"98","author":[{"given":"Michel Pompeu B.O.","family":"S\u00e1","sequence":"first","affiliation":[{"name":"Division of Cardiovascular Surgery of Pronto Socorro Cardiol\u00f3gico de Pernambuco\u2014PROCAPE University of Pernambuco  Recife Pernambuco Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9036-8751","authenticated-orcid":false,"given":"Matheus","family":"Simonato","sequence":"additional","affiliation":[{"name":"Division of Cardiac Surgery Escola Paulista de Medicina\u2014UNIFESP  S\u00e3o Paulo S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jef","family":"Van den Eynde","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Diseases, Unit of Cardiac Surgery University Hospitals Leuven  Leuven Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5407-4553","authenticated-orcid":false,"given":"Luiz Rafael P.","family":"Cavalcanti","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Surgery of Pronto Socorro Cardiol\u00f3gico de Pernambuco\u2014PROCAPE University of Pernambuco  Recife Pernambuco Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ali","family":"Alsagheir","sequence":"additional","affiliation":[{"name":"Division of Cardiac Surgery, Department of Surgery McMaster University  Hamilton Ontario Canada"},{"name":"Division of Health Research Methods, Evidence, and Impact McMaster University  Hamilton Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aspasia","family":"Tzani","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Medicine Brigham and Women's Hospital, Harvard Medical School  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luca Nai","family":"Fovino","sequence":"additional","affiliation":[{"name":"Department of Cardiac, Thoracic and Vascular Sciences and Public Health University of Padova  Padova Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8352-5360","authenticated-orcid":false,"given":"Polydoros N.","family":"Kampaktsis","sequence":"additional","affiliation":[{"name":"NYU Langone Medical Center  USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5356-2996","authenticated-orcid":false,"given":"Michele","family":"Gallo","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery Cardiocentro Ticino  Lugano Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pietro L.","family":"Laforgia","sequence":"additional","affiliation":[{"name":"I.R.C.C.S. Policlinico San Donato San Donato Milanese  Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arjang","family":"Ruhparwar","sequence":"additional","affiliation":[{"name":"Department of Thoracic and Cardiovascular Surgery, West German Heart and Vascular Center Essen University Hospital of Essen, University Duisburg\u2010Essen  Essen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander","family":"Weymann","sequence":"additional","affiliation":[{"name":"Department of Thoracic and Cardiovascular Surgery, West German Heart and Vascular Center Essen University Hospital of Essen, University Duisburg\u2010Essen  Essen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5032-675X","authenticated-orcid":false,"given":"Sameer A.","family":"Hirji","sequence":"additional","affiliation":[{"name":"Division of Cardiac Surgery Brigham and Women's Hospital, Harvard Medical School  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tsuyoshi","family":"Kaneko","sequence":"additional","affiliation":[{"name":"Division of Cardiac Surgery Brigham and Women's Hospital, Harvard Medical School  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gilbert","family":"H. L. Tang","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery Mount Sinai Medical Center  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,2,8]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1814052"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1816885"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehx391"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12928-018-0546-5"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2012.01.390"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehx489"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.28447"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.283.15.2008"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.i4919"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.39489.470347.AD"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.327.7414.557"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/sim.7588"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.2307\/2533446"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.315.7109.629"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCINTERVENTIONS.119.008714"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2016.06.041"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcmg.2015.12.022"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.5603\/KP.a2015.0068"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2015.04.066"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2014.01.412"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2014.09.039"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCINTERVENTIONS.112.000084"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2019.06.037"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1161\/circinterventions.118.007107"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2020.03.022"},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2020.07.005"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.2010.217158"},{"key":"e_1_2_9_29_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehu384"},{"key":"e_1_2_9_30_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.27681"},{"key":"e_1_2_9_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2019.03.031"},{"key":"e_1_2_9_32_1","doi-asserted-by":"publisher","DOI":"10.1161\/circinterventions.120.008972"},{"key":"e_1_2_9_33_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.28720"},{"key":"e_1_2_9_34_1","doi-asserted-by":"publisher","DOI":"10.4244\/eij-d-19-01094"},{"key":"e_1_2_9_35_1","doi-asserted-by":"publisher","DOI":"10.1161\/jaha.120.016446"},{"key":"e_1_2_9_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2007.01.039"}],"container-title":["Catheterization and Cardiovascular Interventions"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccd.29538","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ccd.29538","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccd.29538","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,28]],"date-time":"2023-08-28T16:02:11Z","timestamp":1693238531000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccd.29538"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,2,8]]},"references-count":35,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2021,11]]}},"alternative-id":["10.1002\/ccd.29538"],"URL":"https:\/\/doi.org\/10.1002\/ccd.29538","archive":["Portico"],"relation":{},"ISSN":["1522-1946","1522-726X"],"issn-type":[{"value":"1522-1946","type":"print"},{"value":"1522-726X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,2,8]]},"assertion":[{"value":"2020-12-08","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-01-17","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-02-08","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}